Obstetrics Flashcards
What is the technical definition of parity?
Number of pregnancies that led to a birth beyond 20 weeks gestation, or an infant weighing over 500 g
What is the developmental age of a fetus?
Time since conception–this is usually an unknown quantity
What is the technical definition of gestational age?
Number of weeks and days from LMP
When does the fundal height correspond to weeks gestation?
After 20 weeks
When are fetal heart tones heard?
10 weeks
When does fetal movement begin?
20ish weeks
When is the crown-rump length the determining factor for dating gestational age?
until 12 weeks (so only the first trimester)
What happens to hCG in the second and third trimester respectively?
second = decrease Third = level off
When can a fetus be seen on US (weeks and b-hCG levels)?
around 5 weeks or 1500 hcg transvaginally, or 5000 transabdominally
What is the acceptable amount of weight gain that a mother should gain if they are:
- underweight
- at weight
- overweight
- obese
- underweight = 15 kg
- at weight = 14 kg
- overweight = 9 kg
- obese = 7 kg
What are the definitions of excessive and inadequate rate of weight gain in pregnancy?
Excessive = 1.5 kg/month Inadequate = Less than 1 kg/month
What amount of folate should all women have? What about those with a h/o giving birth to a child with a NTD?
0.4 mg/day
4 mg/day for h/o it
What is the recommended amount of Fe that a pregnant women should get per day, starting at the first prenatal visit?
30mg/day
What is the recommended amount of Ca that a pregnant women should get per day, starting at the first prenatal visit?
1300 mg/day less than 19 years old
1000 mg/day over 19 years
What is the recommended amount of Vitamin D that a pregnant women should get per day, starting at the first prenatal visit?
10 micrograms/day
What is the recommended amount of vitamin B12 that a pregnant women should get per day, starting at the first prenatal visit?
2 micrograms/day
How much exercise should pregnant women get?
30 minutes /day
What happens to the following measurements in throughout the duration of pregnancy:
- Cardiac output
- Heart Rate
- BP
- Cardiac output = increases
- Heart Rate = increases
- BP = decreases
What happens to the following measurements in throughout the duration of pregnancy:
- Tidal volume
- Respiratory rate
- Expiratory reserve
- Tidal volume = increases
- Respiratory rate = constant
- Expiratory reserve = decreases
What happens to the following measurements in throughout the duration of pregnancy:
- blood volume
- Fibrinogen
- Electrolytes
- Hematocrit
- blood volume = increases
- Fibrinogen = increases
- Electrolytes = constant
- Hematocrit = decreases
How often should pregnant women have a prenatal visit throughout their pregnancy?
Weeks 0 - 28 = q4 weeks
Weeks 29-35 = q2 weeks
Weeks 36+ = every week
What are the hematological labs that should be obtained at the first prenatal visit? (3)
CBC
Rh
T+S
What are the infectious diseases should be tested for at the first prenatal visit?
Rubella antibody titer HBsAg RPR/VDRL Gonorrhea and chlamydia PPD HIV Pap smear
What are the prenatal tests that are offered at 9-14 weeks gestation? (3)
PAPP-A
nuchal translucency
beta-hCG
What are the prenatal tests that are offered at 15-22 weeks gestation? (4)
AFP
estriol
beta-hCG
inhibin-A
When is the quad screen offered in pregnancy?
second trimester
When is the full anatomic screen offered in pregnancy?
20 weeks
When is the one hour glucose challenge done in pregnancy?
26 weeks
When is Rhogam given in pregnancy for an Rh - woman with an Rh + fetus?
30 weeks
When is a GBS culture obtains in pregnancy?
35-37 weeks gestation
What are the quad screen results for trisomy 18?
Decreased everything (AFP, estriol, hcg, inhibin A)
What are the quad screen results for Down syndrome?
("2 up, 2 DOWN") Decreased AFP Decreased estriol Increased beta hCG Increased inhibition A
What is elevated maternal serum AFP associated with?
NTDs
Abdominal wall defects
Multiple gestations
Fetal death
When is the triple screen performed?
10 weeks-ish gestation (end of first trimester)
What are the indications for amniocentesis? (4)
- Women over 35
- Abnormal quad screen
- Rh sensitized mother to detect fetal hemolysis
- Evaluate fetal lung maturity
What are the TORCHeS infections?
Toxo Other Rubella CMV Herpes / HIV / hepatitis Syphilis
What is the definition of spontaneous abortion?
Loss of POC prior to 20 weeks gestation
What is the definition of recurrent spontaneous abortions?
Two or more consecutive SABs or three in 1 year
What are the likely causes of spontaneous abortions early and late in the pregnancy?
Early = chromosomal abnormalities Late = Hypercoagulable states
What are the fetal effects of maternal use of: ACEIs?
fetal renal tubular dysplasia
What are the fetal effects of maternal use of: androgens
Virilization of female fetuses, and genital developmental defects in boys
What are the fetal effects of maternal use of: cocaine?
Bowel atresia
Heart or limb malformations
Microcephaly / IUGR
What are the fetal effects of maternal use of: carbamazepine
NTDs
Microcephaly
What are the fetal effects of maternal use of: DES
Clear cell adenocarcinoma of the vagina or cerix
What are the fetal effects of maternal use of: lead
Increased SABs
What are the fetal effects of maternal use of: Li
Ebstein anomaly
What are the fetal effects of maternal use of: methotrexate
SABs
What are the fetal effects of maternal use of: organic Hg
SABs
What are the fetal effects of maternal use of: phenytoin
IUGR
MR
microcephaly
What are the fetal effects of maternal use of: radiation
microcephaly
MR
What are the fetal effects of maternal use of: streptomycin and kanamycin
CN VIII damage
What are the fetal effects of maternal use of: tetracyclines
Yellow discoloration of teeth
What are the fetal effects of maternal use of: thalidomide
bilateral limb deficiencies
What are the fetal effects of maternal use of: valproic acid
NTDs
What are the fetal effects of maternal use of: vitamin A and derivatives
SABs
What are the symptoms of congenital infection with: toxo
Hydrocephalus
Chorioretinitis
Intracranial calcifications
What are the symptoms of congenital infection with: rubella
Blueberry muffin cataracts MR Hearing loss PDA
What are the symptoms of congenital infection with: CMV
Petechial rash and periventricular calcifications
What are the symptoms of congenital infection with: HSV
CNS/systemic infections
What are the symptoms of congenital infection with: HIV
FTT and immunodeficiency
What are the symptoms of congenital infection with: syphilis
Maculopapular rash
SNuffles
Saber shins
Saddle nose
What are the components of the Hutchinson triad of congenital syphilis infection?
Teeth
Deafness
Interstitial keratitis
What is the treatment for congenital infection with: toxo
Pyrimethamine
What is the treatment for congenital infection with: rubella
Symptomatic
What is the treatment for congenital infection with: CMV
Ganciclovir
What is the treatment for congenital infection with: HSV
Acyclovir
What is the treatment for congenital infection with: HIV
HAART
What is the treatment for congenital infection with: syphilis
PCN
What are the s/sx, PE findings, and treatment for complete spontaneous abortions?
- Bleeding and cramping stopped, POC expelled
- Closed OS
- no treatment
What are the s/sx, PE findings, and treatment for threatened spontaneous abortions?
- Uterine bleeding + abd pain
- Closed OS with NO POC passed
- Pelvic rest, f/u US
What are the s/sx, PE findings, and treatment for an Incomplete spontaneous abortions?
- Partial POC expulsion
- Open OS
- Manual uterine aspiration
What are the s/sx, PE findings, and treatment for inevitable spontaneous abortions?
- Uterine bleeding, No POC expulsion
- Open OS
What are the s/sx, PE findings, and treatment for missed spontaneous abortions?
- Cramping, loss of early pregnancy s/sx
- Closed OS, w/o fetal cardiac activity
What are the s/sx, PE findings, and treatment for septic spontaneous abortions?
- Fever, foul smelling d/c
- Fever, hypotension
- D+C and Abx
What is the defintion and treatment for intrauterine demise?
Absence of fetal cardiac activity over 20 weeks gestation
When in the pregnancy can methotrexate be used to end a pregnancy?
49 days
When in the pregnancy can mifepristone and misoprostol be used to end a pregnancy?
49 days
When in the pregnancy can vaginal or SL misoprostol (high dose, repeated) be used to end a pregnancy?
59 days
When in the pregnancy can manual D+C (w/wo suction) be used to end a pregnancy?
up to 13 weeks
When in the pregnancy can induction of labor through prostaglandins / oxytocin be used to end a pregnancy?
13-24 weeks GA
When in the pregnancy can D+E be used to end a pregnancy?
Up to 24 weeks GA
What are the leopold maneuvers used for?
Determine fetal lie and presentation to determine if the pregnancy will be complicated
If ROM is suspected in a women, what exam should be performed?
Sterile speculum examination
What are the aspects of the cervix that are evaluated just prior to Labor? (4)
Dilation
Effacement
Station
Cervical station/consistency
What are the stages of labor?
Engagement Descent Flexion Internal rotation Extension External rotation Expulsion
How often should FHR be obtained in the first and second stages of labor assuming there are no complications?
First = q30 minutes Second = q15 minutes
What defines the latent and active parts of the first stage of labor?
Latent = Onset to 4 cm dilation Active = 4 cm dilation to full (10cm) dilation
What is the average time for the latent and active phases of labor for primiparous and multiparous women respectively?
Primiparous = 9 hours, 6 hours Multiparous = 5 hours, 2.5 hours
What is the average time for the second phase of labor for primiparous and multiparous women respectively?
0.5 - 3 hours for primiparous
5 - 30 mins for multiparous
What is the average time for the third phase of labor for primiparous and multiparous women respectively?
0 - 0.5 hours for both
How often should FHR be obtained in the first and second stages of labor if there are complications?
First stage = q15 minutes
Second stage - q5 minutes
What is the normal fetal heart rate range?
110-160 bpm
What does absent variability of the fetal HR mean?
Indicates severe fetal distress
What does minimal variability of the fetal HR mean?
Less than 6 bpm change, indicates fetal hypoxia Mg, or sleep cycle
What does normal variability of the fetal HR mean?
6-25 bpm
What does marked variability of the fetal HR mean?
Over 25 bpm variations
Indicates fetal hypoxia
What does sinusoidal variability of the fetal HR mean?
Points to serious fetal anemia
What are accelerations in fetal HR? What are the significance of these?
Onset of an increase in FHR over 15 bpm to a peak in less than 30 seconds
Reassuring because the indicate fetal ability to appropriately respond to the environment
When is antepartum fetal surveillance indicated (indications, timeframe)?
IN pregnancies in which the risk of antepartum fetal demise is increased, usually at 32-34 weeks