Gastrointestinal Flashcards
What is oropharyngeal dysphagia?
Problem of initiating swallowing
What is the treatment for oral HSV?
Acyclovir
What is the treatment for oral CMV?
Ganciclovir
What is the treatment for oral thrush?
Fluconazole PO and/or nystatin mouth rinses
What worsens and improves s/sx of esophageal spasms?
Worse with hot/cold foods, better with NTG
What are the typical s/sx of esophageal spasms?
Chest pain
GERD
Dysphagia
Odynophagia
What are the diagnostic test of choice for esophageal spasms? What do they reveal?
Ba swallow–Corkscrew shaped esophagus
Manometry–High amplitude, simultaneous contractions in greater than 20% of swallows
Corkscrew shaped esophagus on Ba swallow = ?
Esophageal spasm
What is the pharmacologic treatment for esophageal spasms? (3)
CCBs
TCAs
Nitrates
What is the treatment for severe esophageal spasms?
Esophageal myotomy
What is achalasia?
Impaired relaxation phase of the lower esophageal sphincter and loss of peristalsis
What is the etiologic of achalasia?
Degeneration of the inhibitory neurons in the myenteric plexus
What are the s/sx of achalasia?
Progressive dysphagia for solids and liquids
Regurgitation of food
What are the tests to diagnose achalasia?
EGD to r/o structural causes
Ba swallow
What will a Ba swallow show with achalasia?
Bird’s beak tapering of the distal esophagus
What will manometry show with achalasia?
Increased resting pressure of the LES
Incomplete LES relaxation
What is the short term pharmacologic treatment for achalasia?
Nitrates
CCBs
Endoscopic injection of botulinum toxin
What is the definitive treatment for achalasia?
Pneumatic balloon dilation or surgical myotomy
Is a Zenker diverticulum a true or false diverticulum?
False
Where does a Zenker diverticulum occur?
Through the cricopharyngeus muscle
What is the treatment for a Zenker diverticulum?
Myotomy
What is the most common type of esophageal cancer worldwide?
SCC
What is the most common type of esophageal cancer in developed nations?
Adenocarcinoma
What is SCC of the esophagus associated with?
EtOH
Smoking
Nitrosamines
Hot tea