Obstetrics Flashcards
What is Goodell sign?
Softening of the cervix in early pregnancy
What is Chadwick sign?
Dark bluish-red discoloration of the vaginal mucosa in the 1st trimester
What are Hegar and Ladin signs?
Softening of the uterus in 1st trimester
What is Chloasma?
Skin hyper pigmentation of the face, often in sun-exposed areas in the 2nd trimester
What is Linea nigra?
Skin hyperpidmentation along the midline of the anterior abdominal wall in the 2nd trimester
What is Naegele’s rule?
- To determine expected date of delivery
- Take 1st day of LMP and add 7 days. Then subtract 3 months. then add 1 year
When can beta HCG be detected in the urine? In the serum?
- Urine=2 weeks after fertilization
- serum=1 week after fertilization
Which teratogen is associated with Ebstein anomaly?
Lithium
Which teratogen is associated with yellow-brown discoloration of teeth?
Tetracyclines
Which teratogen is associated with phocomelia (shortened limbs)?
Thalidomide
Which teratogen is associated with nasal hypoplasia and epiphyseal stippling?
Warfarin
When should a preggo be screened for syphilis?
first visit
-3rd trimester too if high risk
When should a preggo get the quadruple screen?
15-20 weeks
When should a preggo be screened for gestational DM?
24-28 week s
when should a preggo get RhoGAM if Rh(D) negative?
- 28 weeks
- after delivery
- anytime there is potential hemorrhage
When should a preggo be screened for group B streptococcus?
35-37 weeks
What is an elevated AFP associated with?
- neural tube defects
- abdominal wall defects
- multiple gestations
- incorrect dating
Dec AFP, inc beta hCG, dec estradiol, inc inhibin?
Trisomy 21
Decreased AFP, estriol and beta hCG?
Trisomy 18 (Edwards)
When can chorionic villus sampling be done?
10-13 weeks
When can amniocentesis be done?
15-20 weeks
1st line pharmacotherapy for n/v in pregnancy?
pyridoxine (vitamin B6) and doxylamine (antihistamine)
What is hyperemesis gravidarum?
weight loss >5% of pre-pregnancy weight due to n/v
- dehydration, ketosis, and abnormal labs
- get US to r/o gestational trophoblastic disease and multiple gestations
What is the difference between an A1 and an A2 gestational diabetic?
A1=good control of BG with diet and exercise
A2=requires insulin
What ABX are good for asymptomatic bacteruria in preggos?
- nitrofurantoin
- amoxicillin
- caphalexin
- bactrim
- fosfomycin
What is the treatment for a preggo with pyelonephritis?
-IV ABX (amp +gent, ceftriaxone, meropenem, zosyn)
Who should be treated with antibiotics for the duration of the pregnancy?
- women with asymptomatic bacteriuria who failed treatment 2 times
- Women with pyelonephritis x 1.
- Give Nitrofurantoin for the duration of the pregnancy