MSK Flashcards
What is the maximum dose of acetaminophen?
4g/day
What antibody is associated with limited cutaneous systemic sclerosis (CREST)?
anti-centromere Ab
What antibody is associated with diffuse cutaneous systemic sclerosis?
anti-scl 70 Ab (anti-DNA topoisomerase Ab)
What antibody is associated with mixed connective tissue disease?
anti-U1-RNP Ab
What antibody is associated with Rheumatoid arthritis?
ACPA, RF=anti-IgG
What antibody is associated with Polymyalgia Rheumatica?
None. Pt will have a very elevated ESR though
What antibody is associated with polymyositis and dermatomyositis?
anti-jo 1 Ab (anti-synthase Ab)
What antibody is associated with sjogrens?
anti-Ro Ab (anti-SSA Ab) and anti-La Ab (anti-SSB Ab)
What antibody is associated with SLE?
anti-dsDNA Ab, anti-Sm Ab, ANA
What antibody is associated with drug induced lupus?
anti-histone Ab
What are the 4 seronegative spondylarthropathies?
PAIR
- Psoriatic arthritis
- Ankylosing spondylitis
- IBD arthritis
- Reactive arthritis
Needle-shaped negatively birefringent crystals?
Gout
yellow=parallel, blue=perpendicular
Rhomboid-shaped, positively birefringent crystals?
Pseudogout
Drugs associated with drug-induced lupus? What is the antibody?
- SHIPP
- Sulfonamides, Hydralazine, Isoniazid, Phenytoin, Procainamide
-Anti-histone Ab
Rheum disorder with shoulder/hip joint pain and stiffness? What is this associated with? Tx?
Polymyalgia rheumatica
- associated with Giant Cell arteritis
- low-dose glucocorticoids
Labs to check in suspected polymyositis?
Labs: CK, ALT, AST, aldolase
Xerophthalmia and xerostomia are associated with what condition?
(dry eyes and dry mouth)
-Sjogren’s