MSK Flashcards

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1
Q

What is the maximum dose of acetaminophen?

A

4g/day

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2
Q

What antibody is associated with limited cutaneous systemic sclerosis (CREST)?

A

anti-centromere Ab

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3
Q

What antibody is associated with diffuse cutaneous systemic sclerosis?

A

anti-scl 70 Ab (anti-DNA topoisomerase Ab)

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4
Q

What antibody is associated with mixed connective tissue disease?

A

anti-U1-RNP Ab

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5
Q

What antibody is associated with Rheumatoid arthritis?

A

ACPA, RF=anti-IgG

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6
Q

What antibody is associated with Polymyalgia Rheumatica?

A

None. Pt will have a very elevated ESR though

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7
Q

What antibody is associated with polymyositis and dermatomyositis?

A

anti-jo 1 Ab (anti-synthase Ab)

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8
Q

What antibody is associated with sjogrens?

A

anti-Ro Ab (anti-SSA Ab) and anti-La Ab (anti-SSB Ab)

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9
Q

What antibody is associated with SLE?

A

anti-dsDNA Ab, anti-Sm Ab, ANA

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10
Q

What antibody is associated with drug induced lupus?

A

anti-histone Ab

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11
Q

What are the 4 seronegative spondylarthropathies?

A

PAIR

  • Psoriatic arthritis
  • Ankylosing spondylitis
  • IBD arthritis
  • Reactive arthritis
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12
Q

Needle-shaped negatively birefringent crystals?

A

Gout

yellow=parallel, blue=perpendicular

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13
Q

Rhomboid-shaped, positively birefringent crystals?

A

Pseudogout

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14
Q

Drugs associated with drug-induced lupus? What is the antibody?

A
  • SHIPP
  • Sulfonamides, Hydralazine, Isoniazid, Phenytoin, Procainamide

-Anti-histone Ab

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15
Q

Rheum disorder with shoulder/hip joint pain and stiffness? What is this associated with? Tx?

A

Polymyalgia rheumatica

  • associated with Giant Cell arteritis
  • low-dose glucocorticoids
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16
Q

Labs to check in suspected polymyositis?

A

Labs: CK, ALT, AST, aldolase

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17
Q

Xerophthalmia and xerostomia are associated with what condition?

A

(dry eyes and dry mouth)

-Sjogren’s

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18
Q

Proximal muscle weakness and a facial rash?

A

Dermatomyositis

19
Q

Arthritis + oral ulcers + proteinuria

A

SLE

20
Q

What rheum disorder is associated with anti-citrullinated protein antibodies (ACPA)?

A

Rheumatoid arthritis

21
Q

Hand x-ray showing “pencil-in-a-cup”?

A

Psoriatic arthritis

22
Q

Arthritis affecting the DIPs and PIPs?

A

Osteoarthritis (DIP=Heberden’s nodes, PIPs=Bouchard’s nodes)

23
Q

Most common overall cause of osteomyelitis? What to consider in sickle cell? IVDA? In Diabetics?

A
  • overall=s.aureus
  • sickle cell=salmonella
  • IVDA andDM=pseudomonas
24
Q

Cause of bilateral Bell’s Palsy?

A

Lyme

25
Q

What cancers like to metastasize to bone?

A

“Permanently Relocated Tumors Like Bones”

  • Prostate (blastic)
  • Renal cell carcinoma
  • Testes and Thyroid
  • Lung (lytic)
  • Breast
26
Q

X-ray showing Codman’s triangle and sunburst pattern?

A

Osteosarcoma

27
Q

X-ray showing “onion skinning”?

A

Ewing sarcoma

28
Q

X-ray with “soap bubble” appearance?

A

Giant cell tumor (osteoclastoma)

Clast=clean

29
Q

Old man with bowed out legs, hearing loss, increase in hat size? Most sensitive test?

A

Paget’s disease

-Nuclear bone scan for hot spots

30
Q

What type of shoulder dislocation will the arm be held in external rotation and slight abduction? What is a potential complication?

A
  • Anterior dislocation

- Axillary N injury

31
Q

What type of shoulder dislocation is associated with an adducted and internally rotated arm? When do these normally occur?

A
  • Posterior

- seizures and electrocution

32
Q

Nerve at risk with a fracture of the shaft of the humerus? Consequence?

A

Radial Nerve

-wrist drop

33
Q

Nerve at risk with a fracture of the surgical neck of the humerus? Consequence?

A

Axillary nerve

-loss of shoulder abduction

34
Q

Nerve at risk with a supracondylar humerus fracture? consequence?

A

Median N

-“pope’s blessing”–> loss of flexion of the 2nd and 3rd digits.

35
Q

Name for a distal radius +/- distal ulna fracture with a posteriorly displaced radius?

A

Colles fracture

36
Q

Name for a distal radius fracture with a ANTERIORLY displaced radius?

A

Smith fracture

37
Q

Proximal ulnar fracture with dislocation of the radial head?

A

Monteggia fracture

38
Q

Fracture of the distal radius with dislocation of the distal radial ulna joint?

A

Galeazzi fracture

39
Q

Low back pain with radiation that is worse with standing and walking and better with leaning forward?

A

Spinal stenosis

40
Q

Injury causing arm extension and adduction with forearm pronation?

A

Erb-duchenne palsy (waiter’s tip)

-superior trunk injury (common in birth trauma)

41
Q

Injury causing forearm supination and wrist and finger flexion? How does this commonly happen?

A

Klumpke palsy
(inferior trunk injury)

-“klumpke the monkey hung from a tree”–> when falling and grab something it pulls that inferior trunk

42
Q

What is injured in the “unhappy triad”?

A
  • ACL, MCL and medial meniscus

- normally occurs with a medially directed blow to the lateral side of the knee

43
Q

Middle aged man with bilateral calcification of articular cartilage on x-ray. Cause? tx?

A

Chondrocalcinosis 2/2 psudogout

tx: NSAIDS or colchicine