Obstetric Pharm

Question 1

Main 2 complications in preganacy discussed?

Answer 1

obstetric haemorrhage and pre-eclampsia

Question 2

define obstetric haemorrhage

Answer 2

major = more than 1500ml blood loss
sever = 2500

Question 3

what essentially is pre-eclampsia

Answer 3

high blood pressure

Question 4

which extra route of excretion of drugs do pregnant women have?

Answer 4

lactation

Question 5

2 drugs used in obstetric haemorrhage and 2 other interventions. role of drugs?

Answer 5

oxytocin (contracts uterus smooth mucle) and ergometrine (contracts uterus + vascular smooth muscle.
Also need IV fluid and blood transfusion

Question 6

drugs used in pre-eclampsia. roles? what is contraindicated and why

Answer 6

Labetalol (controls hypertension) and magnesium sulphate (treats and prevents seizures).
ergometrine is contra (will increase BP)

Question 7

3 step management of pre-eclampsia?

Answer 7

1. Control of hypertension with antihypertensives.
2. Prevention and treatment of seizures with MgSO4.
3. Meticulous fluid balance.

Question 8

3 step management of obstetric haemorrhage

Answer 8

1. Control the bleeding .
2. Restore adequate oxygen carrying capacity.
3. Maintain adequate tissue perfusion.