obesity Flashcards
statistics
BMI>30, 39% 20+adults, 71%overweight
multifactorial
some genetics, some society, gene: congenital leptin
weight loss
eat less move more» more complex than that!!
fat storage
set point, - body defends agains fat change
metabolic adaptation
restrict calorie, decrease energy expenditure, increase hunger. obesity increases insulin/leptin/glucagon/glip, decrease gherkin, glucagon, pept
diet and fat storage
calories aren’t equal, low fat diet> didn’t maintain loss, sugar^ insulin, protein decrease grueling
weight losss treatment goals
5-10% weight loss improves cardio metabolic health, decrease calories, maintain protein
parts of intervention
diet/physical activity, pharm, surgery
diet/physical activity
low carb: quick effect maintain, low fat= rebound (sugar carb sub?), replacement food depends
pharm
meds underused. BMI >30 or >27 with comorbitities. reassess at 3 month (5% weight loss)
surgery
effective but some requain
weight loss surgeries
gastric band, sleeve (best) roux en y bypass, bioopanc (greatest risk, largest impact)
medication names
orlistat, phentermine, liraglutide (DM)
ketosis
may accelerate weight loss and helming insulin. cholesterol, headache, fatigue… not safe in DM