Obesity Flashcards
Obese % by race
Women: Black- 54%
Hispanic: 32%
White: 30%
Children: black 24.5%
Hispanic: 22.1%
BMI
Kg/m2
In x .0254 = m
Lb \ 2.2 = kg
> 25 overweight
30 obese
40 morbidly obese
Fat cell hypertrophy
Hyperplasia
- existing fat cells enlarge/ fill with fat
- total number cells increases:
> obesity during adolescence
> 40 + BMI
Women average 30lb gain 25-34 yrs old
Obesity deaths
280k- 325k premature deaths/yr
- lose 10-20 yrs off life
- adolescence obesity cause health risk issues even if obesity does not continue
- 4-10% increase in bw = 50% ^ risk coronary disease
Android obesity
Gyroid obesity
- abdominal gain
> coronary disease, HPB, diabetes - hip, thigh, butt - lower risk
(Abdominal fat enters blood stream easier)
Body fat distribution pattern:
WHR
WG
- waist at smallest point (near navel) divided by hip at largest point
> .80 (w) or .95 (m) = android (bad)
W> 30in - 2x more likely heart disease
M > 40in, W > 35 - elevated risk profile
Active overeating
Passive overeating
- cognitive drive to over consume (in or external)
> defect in satiety/ appetite regulation - normal food intake becomes excessive because of sedentary lifestyle
Thermogenic requirements by macro
Fat- 0-2%
Protein- 25-30%
Carb- 6-8%
Lower calorie with higher protein- weight loss, lean muscle, cardiac health
Volumetrics
- Huge portion size, better priced than smaller size, too many calories for single meal
- option of larger meal makes people consume 432 more calories a day
Basal metabolic rate
BMR
- Energy required for living- 60-70% daily expenditure
- food- 10%
Activity/ exercise- 15-30%
*key to fighting obesity- NEAT - spontaneous physical activity (park further, take stairs, stand at desk, walking meeting)
NEAT
(Larger person can burn extra 350 calories due to weight if adopt active NEAT
- walking meeting, sand desk,, 15min walk once get home/after eat/ after school, stairs
Leptin
- cytokine hormone- secreted by adipose tissue
- appetite regulator (increase in fat > release Leptin > trigger hypothalamus > reduce appetite
- transport impaired in obese
Cholecystokinin
- secreted in duodenum + jejunum
- slows emptying of stomach - satiety signals to hypothalamus
- possible appetite suppressing supplement
Ghrelin
- produced in stomach- stimulates appetite
- stimulates hGH
- inverse relation with body weight
Peptide yy
- hormone released from colon/rectum proportionate to calories consumed
- acts on hypothalamus to suppress appetite
- on pancreas to excrete exocrine secretion of digestive juices
- on gallbladder to release bile
- more slowly than ckk more rapid than Leptin
- obesity limits excretion