Obesity Flashcards
Body Mass Index (BMI)
kg/m^2
Correlates well with body fatness in general, simple to assess.
One unit of BMI is about..
6 or 7 pounds for most people
How much of the US population is overweight or obese
60%
70% of obese people suffer from…
at least 1 other health problem, most commonly, diabetes.
How many people die each year from obesity related problems
300,000
What was the most notable shift in the 2007 expert report on food, nutrition, physical activity, and the prevention of cancer? (from 1997)
The increase in emphasis on obesity as a risk for many types of cancer, and a target for treatment/intervention.
Is visceral or subcutaneous fat better?
Subcutaneous fat is better than visceral.
apples are worse off than pears, android is worse than gynoid
Why is visceral fat worse?
It releases fatty acids more readily, even if it’s not needed by the muscle.
What happens to unused fatty acids?
They are cleared by the liver to make VLDL triglyceride, and then gets sent back to the fat tissue to be stored.
Is it better to be insulin sensitive or insulin resistant?
Insulin sensitive!!!
Resistance is a continuous spectrum.
What is hypertriglyceridemia?
Insulin Resistance.
Stored triglycerides from fat cells (especially visceral fat) are released and getting repackaged into vLDL and going back to fat for tissue.
Insulin sensitivity/resistance study (Cornier)
- hi carb/ lo fat is more effective for insulin sensitive women
- lo carb/hi fat is more effective for insulin resistant women
- low GL is more effective than high GL for insulin resistant adults, but not insulin sensitive adults.
Having 3 or more/5 of these symptoms (abdominal obesity, hypertension, elevated fasting glucose, elevated triglycerides, and low HDL cholesterol) is an indicator of
Metabolic Syndrome
Conclusion of the Sacks et al Study looking at variations of carb/fat/protein
Reduced calorie diets result in clinically meaningful weight loss regardless of which macronutrients they emphasize
A to Z weight loss study
~30kg RANGE of weight change WITHIN each diet group