OB/Gyn Flashcards
Criteria for discharge post surgery
Alert Ambulatory (to BL level) Adequate po intake Stable vitals Satisfactory bowel/urinary fxn
What is footling breach?
Post membrane rupture, one single foot extending through the vaginal canal
What is lochia?
Normal shedding of endometrium after delivery of placenta
red (lochia rubra) -> pinkish/brown (lochia serosa) -> yellowish white (lochia alba)
Lasts 6-8 weeks post partum
Risk of vertical HIV transmission in a HIV + mom who declines ART delivery and c-section
25%
HIV + moms should receive ART and c-section
* 8% if ART alone and 2% or less in ART and c-section
Pt has bleeding, pain, and hCG in the 400’s. U/s negative. Now what?
Recheck BhCG in a couple of days. Pregnancy rarely visible on U/s when < 1500.
Visualize in a couple of days to identify if ectopic pregnancy
Mom at 27weeks is + for Syphillis. What next?
Confirm with MHA-TP (treponemal-specfic confirmatory test, more specific than RPR)
If this is also positive - tx mom for syphilis
Tx with penicillin. If allergic undergo penicillin desensitization
A pt presents with twins, one vertex one breech. What are the Method of delivery options?
Successful vaginal delivery is likely as long as the breeched twin is the same size or smaller than the vertex.
RhoGAM is indicated anytime mom is ___ and baby is ______
Mom is Rh- and baby is Rh+ regardless of blood type
Administer at 28wks and at delivery.
Failure = fetal hydrops
Pt has:
more than 5 contractions/10 min
Contraction lasting 2+ minutes
Contraction of normal duration within 1 minute of each other. dx?
Uterine hyperstimulation
d/c oxytocin (causes non reassuring fetal hr tracing)
half life = 3-5 min
Two malignant tumors that occur after abortion, ectopic pregnancy, or preterm/term pregnancy
Choriocarcinoma
Placental site trophoblastic dz
Management of hyperemesis gravidarum?
pyridoxine-doxylamine followed by promethazine and/or ondansetron
Pregnant woman AMS, RUQ pain, elevated LFTS, ABN coags. Dx?
Acute fatty liver of pregnancy
Microvesicular fatty infiltration usually occurring in late pregnancy.
presents with n/v, abd pain, jaundice
Why is vitamin A supplementation contraindicated in pregnancy?
Increased risk of cranial neural crest malformations.
Can be considered in strict vegans and immigrants
Mom presents in 3rd trimester for first prenatal visit also has HTN. Most likely finding on U/S?
Normal head and small abd circumference
Occurs due to diminished uteroplacental blood flow
Maternal hypothyroidism predisposes baby to?
pregnancy loss Pre-eclampsia Placental abruption Low birth weight perinatal mortality Neuropshyc impairment
Preggo with C-section history presents with bright red painless bleeding. Dx and at risk of?
Placenta previa
Massive hemorrhage
Usually plan a C-section at 35-36 weeks after confirmation of fetal lung maturity
Painless vaginal bleeding post sexual activity in a preggo. Dx and assessment?
Placenta previa
Do an abd U/S
Digital exam is contra -> worsens the bleeding
RF’s of previa are multiparity and C-sections
Cause of fetal deceleration during delivery?
Cord compression
What supplement should a woman take while she is trying to get pregnant?
Folic acid 0.4 mg QD
Prevents NTD
Preggo presents with painful vaginal bleeding following a trauma. Fetal heart rate 160. Dx?
Moderate placental abruption
What is an acceptable amount of radiation to expose a preggo to?
5 rad
Why do most preggo’s have a low HCT?
Decreased Serum:RBC ratio
Volume expanded
What should be measured following a spontaneous abortion that has been confirmed by U/S?
Serial BhCG to rule out ectopic preggo
Postpartum mom has little interest in her baby. Dx and Tx?
Post partum depression
Antidepressants and psychotherapy
When should a prophylactic cerclage be removed?
36-38 weeks gestation
This is when fetal lungs are considered mature
If a mother continues to bleed postpartum despite fundal massage, dx and tx?
uterine atony
Associated with late delivery, large baby, multiparity, long labor
Soft boggy bloody uterus
Tx - Oxytocine, IM methergine, carboprost, and misoprotol
Should you culture a pt that had a positive GBS urine in her first trimester and a previous baby that had GBS sepsis?
No. Just give intrapartum penicillin
When is the earliest you can karyotype a fetus?
10 weeks - chorionic villus sampling (CVS)
15 week - amniocentisis
Triple marker screening not considered definitive, just suggestive
Should a preggo be treated for aymptomatic UTI?
Yes. Nitrofurantonin. Do this to prevent pyelo
Untreated UTI also predisposes to low birth weight and prematurity
What should you do after D&C of a complete molar preggo?
Follow BhCG until it falls to zero
Then place pt on OCP and follow BhCG monthly to evaluate if there is a metastatic process
What do you do for a fetal demise?
Induce labor
Fetal demise = death in a fetus > 20weeks gestation. Usually from chromosomal anomaly but there are many causes
32 wk gestation with PPROM and lecithin:sphingoid of 1.5:1. Now what?
IM Betamethasone
PPROM with incomplete fetal maturity (ratio should be 2:1)
If a near term fetus does not have appropriate accelerations, what evaluation should you do?
Biophysical profile
Assess: fetal movement, fetal tone, fetal breathing, AF volume, and results of non-stress test
8-10 = baby is ok
Chorionic villous sampling increases risk of what?
Infant limb defects
Vaginal bleeding in the first trimester without fetal loss is?
Threatened abortion
Some bleeding, risk of miscarriage, but baby is still ok
About half will advance to complete abortion
Woman feels a gush of fluid. On PE no pooling of fluid in the vagina or ferning pattern. Dx?
Involuntary loss of urine
PPROm would have pooled fluid in the vag and a ferning pattern on a dried slide
If a woman becomes preggo within a month of receiving the MMR vaccine, is this reason to terminate the pregnancy?
No. The risk is small and shouldn’t warrant termination by itself.
During induced delivery baby has late decelerations. Why?
Fetal academia, late decelerations are not reassuring.
Correct by d/cing uterotoning drugs (ie oxytocin), add IVF, add oxygen, or change mom’s position
During delivery baby has moderate to severe decels. Now what?
C-section
Baby appears to be in distress
Why is a classic C-section scar contra for trial of vaginal birth?
they have 10% risk of uterine rupture.
Perform an amnio at 36-37 weeks to confirm lung maturity prior to scheduling section.
How is arrest of active labor defined?
> 3cm dilation = active phase
no cervical change in >4 hours with adequate contractions or >6 hours with inadequate contractions = arrest of labor
Consider adding pitocin for augmentation
What should be monitored in a preggo for 24 hours post trauma (ie MVA)
Fetal heart tones
Vaginal bleeding
Uterine tenderness
RF’s and management of IUGR
RF’s - uncontrolled HTN, congenital kidney/lung dz, abn karyotype,
Management - Induce labor esp if mom has HTN
Preggo has anxiety, NL TSH but high total T4. What should you do?
Reassure her. She is euthyroid (NL TSH) and her T4 is elevated because of elevated estrogen of pregnancy.
A fetus over 4500 g is considered
Macrosomia
offer a C-section to prevent clavical and brachial plexus injury
Tx for mastitis?
Dicloxacillin
Female has dyschezia (painful defecation), dyspareunia (painful sex), and dysmenorrhea. Dx?
Endometriosis
Dx through direct obs during laparoscopy
Tx for dysfunctional uterine bleeding in a hemodynamically stable pt?
High dose estrogen and progesterone
Give IV estrogen if unstable
Most common cause of a vaginitis in a young girl (ie less than 10)
Foreign body
Most common site of endometriosis?
Ovaries
Can present with nodularity of the uterosacral ligaments
Management of high-grade squamous intraepithelial lesion (HGSIL) on Pap smear?
Colposcopy to get bx and stage the lesion.
Vaginal itching with thining and atrophy of the skin?
Lichen sclerosis
Tx - topical clobetasol or halobetasol
At what point in pregnancy does cervical insufficiency become concerning?
2nd trimester (16 weeks)
What are good prognostic factors in a bx of a breast lump?
less than 2 cm
No lymph nodes
estrogen and progesterone receptors (responds to tamoxifen)
Carcinoma in situ
When should GBS screening be performed?
between 35 and 37 weeks
Leak of urine due to involuntary bladder contraction?
Urge incontinence
Feel like they need to pee all the time because of detrusor overactivity
1st line tx - frequent voiding and kegals
2nd line - anticholinergics (tolterodine)
How do you treat breast cancer in a preggo?
Same as a non preggo but:
NO chemo in 1st trimester
NO radiation therapy
Appropriate chlamydia tx in a preggo?
Azithromycin
Essential to treat to prevent neonatal conjunctivitis and PPROM
retest 4-6 weeks later to confirm cure
Large uterus with endometrial glands within the myometrium
Adenomyosis
Following an endometrial bx, pt has severe abdominal pain. Why?
Uterine perforation
U/s will reveal fluid collection posterior to the uterus
More common side effects - cramping, vaso-vagal rxn
When is LEEP indicated?
For therapeutic removal and bx of cervical lesions
Outpatient with local anesthesia
Complications - minor bleeding, infection.
Later complications - cervical stenosis, cervical incompetence
How do you manage ovarian torsion?
Laproscopy to prevent necrosis
Pt presents with intermittent lower quadrent pain, large ovary on U/S
Two major RF’s for UTI
Sex
hypoestrogenism - give estrogen as a preventative
Abdominal pain/tenderness, Cervical motion tenderness, adnexal tenderness. Dx?
PID
Can also have fever, elevated ESR, leukocytosis
Breast mass that gets very large but does not involve skin, nodes, or chest wall.
Cystosarcoma phyllodes
Usually benign
Pt has amenorrhea and galactorrhea. What is this concerning for?
Pituitary adenoma
Order an MRI
Tx - DA agonist (bromocriptine, cabergoline)
How do you DVT prophylax a non preg pt that has cancer?
Cancer = Hypercoagulable
Enoxaparin and warfarin with INR goal of 2-3
What is physiologic leukorrhea?
Thin white discharge in a otherwise healthy female
Seen in neonates shortly after birth
Also seen in young girls months prior to menarche
Caused by increasing estrogen levels
Management for a fibroid pt that may still want to have children?
Myoectomy
Presents with pelvic pressure, menorrhagea, anemia
Pap smear reveals atypical squamous cells of undetermined significance (ASCUS). Now what?
2 options:
- Repeat cytology in 1 year - use this when HPV testing has not been done
- Do HPV-DNA testing - if + for 16, 18, 31, 33, 35 then colposcopy
What is premenstrual dysphoric disorder? (PMDD)
combo of physical and emotional syx within a week of starting menses
abd bloating, breast tenderness, HA, dizziness
Labile mood, food cravings, increased appetite
Fxn of tamoxifen
Estrogen receptor modulator (agonist in uterus, bones, and liver; antag in breast tissue)
If a pt develops atypical hyperplasia d/c tamoxifen
First sign of precocious puberty in a female?
Thelarche (boobs) -> adrenache (hair) -> growth spurt -> menarche
Occurs at < 8y/o in females
First sign of precocious puberty in a male?
Testicular growth -> penile growth -> adrenarche (hair) -> growth spurt
<9 y/o in males
What is the primary AE of tamoxifen?
Endometrial changes
Increases bone density
Hirtuism + oligomenorrhea + Infertility + Obesity
PCOS
Also IR (acanthosis nigricans)
Tx - weight loss, DM screening, BP and lipid control, metformin, and thiazolidinodiones
Morphology of chlamydia
GN Intracellular bacteria
Infect squamocolumnar epithelial cells
How do you tx a pt with gonorrhea?
Azithromycin + ceftriaxone
azithro for chlamydia
ceftriaxone for gonorrhea
Pt continues to bleed despite fundal massage. Now what?
Give oxytocin to stop uterine atony
Significant postpartum hemorrhage >500mL
Best way to evaluate vaginal bleeding in a preggo
Abd U/s
During labor baby hr falls to the 70s and the umbilical cord has prolapsed. management?
Prolapsed umbilical cord is an obstetric emergency.
STAT c-section
Mom has seizure at 32 weeks. Now what?
Infuse Mg sulfate 6g x 15min to stabilize mom
Then deliver baby
If a preggo fails the 1hr glucose tolerance test, what do you do?
Schedule a 3 hour test
Normal 1 hr test is <140
Some Asian moms get darkened skin after pregnancy. What is ti and management?
Melasma (chloasma)
Common in darker skinned individuals and worsens with subsequent pregnancies
Avoid sun and wear sun block
Tx- hydroquinone
Rh- mom received Rhogam at 28 weeks. Why would you give another dose during this pregnancy?
Exposure to fetal blood (perform E-rosette test)
Causes of DIC during pregnancy
abruptio placentae, saline-induced therapeutic abortion, retained fetus syndrome, and initial phase of amniotic emobolism
How does hypothyroidism affect menstration?
Anovulation and irregular bleeding
Anovulation is due to unopposed estrogen and this leads to an unstable endometrium with irregular bleeding
Ovarian enlargement due to cysts and third spacing
Ovarian hyperstimulation syndrome (OHHS)
Often seen in women needing fertility treatment
Tx - supportive care and prevent thromboembolic dz
MOA of acyclovir
Nucleoside analogue that inhibits viral DNA polymerase
What do you do if a preggo has an abn pap smear?
Get a colposcopy
Treat them the same as a non preggo
T2DM begins having involuntary loss of urine and incomplete emptying
Hypotonic bladder (overflow incontinence) Neuropathy -> loss of innervation to the bladder
Recommended outpt tx for uncomplicated UTI?
po Bactrim x 3 days
How do you manage PID in pregnancy?
Admit to the hospital
IV clindamycin and gentamicin
Pt has PID with severe leukocytosis and fever. Y/s reveals ovarian mass
Tubo-ovarian abscesses (TOA)
Caused by PID ascending to the ovary or after pelvic surgery
Tx - IV abx and possibly surgery
How do you rule out endometrial cancer in a post menopausal woman with vaginal bleeding?
Endometrial bx
Best tx for urge incontinence?
Urge incontinence = unexpected immediate need to void
1st line = pelvic flood exercises and bladder training (Kegel’s and timed voids throughout the day
Painless genital lesion caused by GN encapsulated bacteria
Klebsiella granulomatis Donovanosis Usually found in the tropics Painless papules that ulcerates over weeks Tx - Bactrim, doxy x 3wks
Hormonal abnormalities in PCOS
Increased Test
Decreased Sex hormone binding globulin
Increased LH:FSH (>1)
1 yr after pregnancy a woman is yet to start her periods again. TSH and Prolactin WNL. Why?
Secondary amenorrhea
Can occur after pregnancy due to inadequate progesterone or estrogen
Challenge with IM progesterone, if no bleeding after a week give estrogen and progesterone
What causes dysfunctional uterine bleeding and how do you treat?
Cause - anovulation, unopposed estrogen -> endometrium becomes unstable and sloughes randomly
Tx - (if hemodynamically stable) po cyclic progestins on days 14-25 of cycle or OCPs
Struma ovarii are associated with what hormone change?
Decreased TSH
Ovarian teratoma
Unilateral
Predominantly thyroid tissue
What do you do if you dx bacterial vaginosis in a preggo?
Po metronidazol
top metro and not treating are both associated with preterm labor
Post menopausal woman has vaginal bleeding and bx + for endometrial adenoma. What do you do?
Hysterectomy
B/l adnexectomy
Lymph node sampling
Tx for premenstrual dysmorphic disorder?
SSRI’s (Fluoxetine)
QD or only when symptomatic
17 y/o has primary amenorrhea. On PE, normal external genitalia with short vagina, no uterus
Mullerian agenesis (Mayer-
rokitansky Kuster Hauser syndrome)
Lack of Mullerian stuctures - uterus, fallopian tubes, cervix, upper vagina
Use of OCP’s x 3 years reduces risk of?
Endometrial cancer
Reduces risk by 50%
How frequently should women 50-70 undergo mammography?
Yearly
How should you workup a girl that has long periods and gets anemic?
Get a coag panel
PCOS pt is able to conceive on clomiphene but loses the babies at ~20 weeks. Now what?
Examine with saline-infused sonohysterogram (SIS) to see the contours of the uterus
Breast with redness, fullness, peau d’orange
Inflammatory cancer of the breast
Malodorous greenish-gray vaginal discharge
Trichomonas
Flagellated protozoan
Strawberry cervix
COD in ovarian teratomas?
Torsion,
A couple struggling with infertility have an abn sperm count. Now what?
Repeat sperm count in a few weeks.
Tall female without pubic hair or menstration
Androgen insensitivity
46 XY
Blind-end vaginal pouch and breast development
Androgen insensitivity is at great risk for which malignancy?
Testicular
Intra-abdominal
Need a bilateral gonadectomy at puberty
What should you do following a pap with low-grade or high-grade squamous intrepithelial lesion?
Colpoxcopy with endocervical curettage in non preggo’s
Young sexually active woman with abdominal pain
Dds: appendicitis, pelvic inflammatory dz, ectopic pregnancy, ovarian torsion, corpus luteum cyst formation
How long is the copper IUD effective?
10 years
Contra’s: pelvic infection w/in last 3 months
Post surgery pt is febrile and unresponsive to multiple abx
Septic pelvic thrombophlebitis
Post op or post partum infected thrombosis of the deep pelvic or ovarian veins
Tx- anticoags and broad spectrum abx
Pre-eclampsia with migraine, visual changes, elevated LFTs, elevated Cr.
Pre-eclampsia with severe features (ie end organ damage)