Neuro - uworld Flashcards

1
Q

Which nerve is involved in ocular sensation?

A

Trigeminal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Pt felt warm and nauseous prior to a syncopal episode

A

Neurocardiogenic (or vasovagal) syncope
Occurs due to excessive vagal tone
Preceded by n/v, bradycardia, or pallor
Precipitated by pain or stress

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How do you correct over coagulation in a warfarin pt

A

Vit K and prothrombin complex concentrate (has Vit K dependent clotting factors)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Initial Tx of Guillain-Barre?

A

IVIG or plasmaphoresis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Wacky, wobly, wet

A

normal pressure hydrocephaly

Enlarged ventricles on MRI but normal opening pressure on LP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Dystonia of the SCM

A

Torticollis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Pt develops decreased hearing acuity and vestibular syx weeks after starting abx

A

Aminoglycoside (gentamicin) toxicity - hearing loss and vestibular syx
oscillopsia - sensation of objects moving in the visual field

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Pt has consistent dull HA, decreased libido, and hemianopsia

A

Craniopharyngioma
Benign suprasellar tumor with visual defect, HA, and syx of pituitary changes
Arise from the remnant of Rathke’s pouch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Bitemporal heminopsia

A

Optic chiasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Young obese female with constant dull HA and papilledema

A

Pseudotumor cerebri
Brain tumor w/ NL imaging and elevated CSF pressure
Tx - weight reduction and acetazolamide
If untreated - blindness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Causes of chemo induced peripheral neuropathy

A

Vincristine (Vinca alkaloid)
Cisplatin (platinum)
Paclitaxel (taxanes)
symmetrical parathesia in stocking and glove pattern

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Pronator drift tests?

A

UMN or Pyramidal tract dz dz of the UE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Affected eye is unable to adduct and the contralateral eye abducts w/ nystagmus

A

Internuclear ophtalmoplegia
Convergence is preserved
Damage in the MLF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Worsening frontal HA’s, blurred vision when leading forward

A
Intracranial HTN (ICH
Can have HA, n/v/ AMS,
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

ALS involves damage to?

A

the UMN (spasticity, hyperreflexia) and LMN (fasiculations)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Following a minor skin break in the face pt has severe HA, periorbital edema, EOM deficits

A

Cavernous sinus thrombosis

Edema because the venous system in the cavernous sisnus does not have valves

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What finding confirms CNS lymphoma in a HIV +?

A

EBV DNA in the CSF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

CT reveal global cerebral atrophy that is worse in the temporal and parietal lobes

A

Alzheimers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Parkinson’s is caused by an accumulation of

A

alpha synuclein w/in the substantia nigran

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

3 classic signs of PD?

A

resting tremor
rigidity
Bradykinesia
Best way to dx - at least two of these on PE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Pt has sparse and non fluent speech, impaired repitition, but can follow commands

A

Broca aphasia
can have right hemiparesis
Affects dominant temporal lobe (ie, R handed man, L hemisphere is dominant)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Lots of words w/o meaning, not able to follow commands, poor repeating

A

Wernicke aphasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Fluent but with phonemic errors (sunny vs. funny), able to follow commands, no repeating

A

Conductive aphasia

Can see this in severe forms of Broca’s aphasia that extends to the arcuate fasciculus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

loss pain and temp on ipsi face, contra body
Vertigo, nystagmus
ipsi hornor’s syndrome

A

Lateral medullary infarct (Wallenberg syndrome)
Occlusion of the PICA or intracerebral vertebral a.
Motor function is spared

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Acute, unilateral, severe retro-orbital pain that wakes a pt up

A

Cluster HA
tx - oxygen
Ppx - verapamil, lithium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Pt with new onset CVA syx has a negative CT, now what?

A

Give TPA
Negative CT means non hemorrhagic so give TPA for best neurologic outcomes
Contra’s - hx of intracerebral bleed, BP>185/110, Platelets <100,000
INR>1.7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Pt is treated for CVA w/ sudden loss of contra senses, weeks later now has burning pain and develops allodynia (excessive pain in response to light touch) on the affected side

A

Thalamic pain syndrome
Pt likely had a Lacunar stroke of the posterolateral thalamus (pure sensory lacunar stroke)
Occlusion of deep branches of the PCA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Elderly w/ onset of confusion and lethargy x hours and hyperdense mass in parietal lobe

A

Parietal lobe hemorrhage

Most likely cause is - cerebral AMYLOID angiopathy. Most common cause of spontaneous lobar hemorrhage in an adult >60

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Pt has months hx of right hand clumsiness and decreased sensation over 4th and 5th fingers

A

Ulnar n. syndrome
Clumsiness = weak grip
ulnar n. entrapment in the medial epicondylar groove (elbow)
Entrapment is typically caused by leaning on the elbows during work (for long periods, ie, at a desk or table)
Apparently extremely high yield for USMLE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Most common dementia in the US?

A

Alzheimer’s
Early memory and visospatial impairments
Can have gait impairement in advanced dz

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Blindness in one eye

A
optic n. damage (pre chiasm)
#1
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Loss of left visiual field in each eye

A

Left homonymous hemianopia
Optic tract damage (post chiasm) OR
loss of optic radiations (temporal AND parietal)
#3 or #6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

loss of bottom left corner of visiual field in each eye

A

Left inferior homonymous quadrantonopia

Defect in parietal optic radiations (usually #4)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Loss up top left corner of visual field

A

Left superior homonymous quadrantonopia

Defect in optic radiations to the temporal lobe or Meyers loop #5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Loss of left half of visual field with sparing of the center of vision

A

Left homonymous hemianopia w/ macular sparing
Defect in occipital cortex
Usually #7 or most posterior option

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Papilledema refers to swelling of the

A

Optic disc

Caused by increased ICP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

Ipsilateral optic disc atrophy due to compression by a space occupying lesion in the frontal lobe
papilledema in contra optic disc due to increased ICP

A

Foster-Kennedy syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

Morning HA, transient visual oscuration

A

Increased ICP

Caused by space occupying lesion (tumor, AVM, anuerysm, pseudotomor cerebri (IIH))

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

Large blind spot with intact visual acuity

A

Drusen (pseudopapilledema)
Caused by small hyaline concretions
Fundoscopic exam - glistening hyaline bodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Painful visual loss that is worth with hot baths or exercise, retro-orbital pain

A

Optic neuritis
Suggestive of demyelination
tx - IV methylprednisone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Sudden painless visual loss in pt >50 w/ HTN or DM

A
Ischemia (AION)
Vascular cause (occlusion, TIA) or temporal arteritis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Misalignment of the eyes

A

strabismus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

What does the doll’s eyes test assess?

A

Useful in unconscious pt to evaluate integrity of the vestibular and oculomotor apparatus
Tests vestibulo-ocular movement, CN III, IV, and VIII
If intact, the reflex will rotate the eyes in the direction opposite of the head movement
Suggests nuclear dysfunction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

horizontal gaze center

A

Paramediane Pontine reticular formation (PPRF)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

Defects in MLF produce?

A

INO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

Defect in PPRF and ipsilateral MLF

A

one-and-a-half syndrome

Gaze palsy to the ipsilateral side and INO in contralateral gaze

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

Vertical gaze center

A

riMLF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

What is saccades?

A

Rapid conjugate movement of the eyes to look at objects

Defect - oculomotor apraxia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

How do you tell if nystagmus is central or peripheral?

A

Peripheral - unilateral

Central - bilateral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

Initial Tx for symptomatic myasthinia gravis?

A

Pyridostigmine
Achesterase inhibitor
If resistant - add an immunosuppresive like a steroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

Pt present to ER w/ new onset seizure. Now what?

A

labs - electrolytes
Utox
CT w/o contrast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

Pt has stroke syx quickly followed by n/v

A

Suggestive in intracrainial hemorrhage. n/v because of increased intracranial pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

Age-related hearing loss

A

Presbycusis
Progressive, b/l, symmetric
Sensorineural loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

What deficits are found in DM?

A

alterations of sensation and proprioception

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

How do you work up idiopathic UMN findings?

A

MRI of the spine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

Most likely cause of hemorrhagic stroke in a hypertensive pt?

A

hypertensive vasculopathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

Fever, general muscle rigidity, autonomic instability, AMS

A

Neuroleptic malignant syndrome
Life threatining idiosyncratic drug rxn to DA antagonists
Look for a recent schizo or psychosis episode that would lead to taking an antipsychotic (usually in last 2 weeks), especially 1st gen antipsychotic (haloperidol)
Type B rxn - INdependent of drug dose
Tx - remove aggravating agent and provide supportive care +/- Dantrolene as needed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

What are the two ways that MS will present?

A
  1. optic neuritis - mononuclear blindness, painful eye movement
  2. Transverse myelitis - motor and sensory loss below the level of the lesion, incontinence
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

Tx for depression w/ pseudodementia

A

SSRI

Psedodementia is a reversible cognitive impairment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
60
Q

When do you order an MRI for a pt with a hx of HA’s?

A

When the HA differs in character from the prior
Present when awakening in the morning
Causing frequent nausea, vomiting, or blurry vision
New seizure, AMS, new HA at >40, trauma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
61
Q

Pathophysiology of normal pressure hydrocephaly

A

Decreased CSF absorption -> transient increase in ICP causing ventricular enlargement w/o chronically increased pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
62
Q

Stroke presenting with unilateral motor impairment

A

Posterior limb of internal capsule (lacunar infarct)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
63
Q

Stroke involving contra motor (face arm leg)
Eye deviates toward the lesion
Homonymous hemianopia

A

MCA occlusion
Aphasia when affecting dominant hemisphere
Hemineglect when affecting nondominant
Can affect upper and lower extremities but usually upper is worse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
64
Q

Stroke involving sensory and motor of lower extremity
Abulia (lack of will, initiative)
Dyspraxia, emotional distubrance, urine incontinence

A

ACA occlusion

Can involve upper and lower extremities but usually the lower is worse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
65
Q

Stroke contra hemiplegia and ipsi CN involvement

ataxia possible

A

Vertebrobasilar system lesion

Supplies the brain stem, so think more basal fxn deficits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
66
Q

Stroke presenting with homonymous hemianopia
Visual hallucinations
Sensory syx
CN III palsy

A

PCA occlusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
67
Q

Pathophys of lacunar strokes

A

Microatheroma formation and lipohyalinosis of the small penetrating arteries
RF’s - HTN, HLD, DM, and smoking
Pure motor hemiparesis = internal capsule
Often CT negative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
68
Q

Parkinson’s is a progressive loss of dopaminergic neurons in the

A

Basal Ganglia

Interrupts the neurologic connections between the thalamus and motor cortex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
69
Q

MG is caused by autoAb’s against ACh receptors at the

A

Motor end plate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
70
Q

What gait is characteristic in PD?

A

Shuffling gait (hypokinetic)

71
Q

Essential findings to declare brin death

A

Absent cortical and brain stem fxns

However spinal cord can still be fxn’ing so DTR’s may be present

72
Q

Side effects of amitriptyline

A
Orthostatic hypotension (alpha andrenergic), lethargy (H1), anticholinergic syx (M1; dry mouth, constipation, urinary retention)
Tx - d/c TCA
73
Q

Exaggerated hip and knee flexion while walking

A

“steppage” gait
Common peroneal neuropathy
L5 radiculopathy

74
Q

Cancer that commonly metastasizes to brain in a male

A

Lung
MRI - multiple well-circumscribed lesions with vasogenic edema ant the gray white matter junction
Look for hx of tobacco use + new onset seizures

75
Q

Acute onset of vertigo, n/v

A

Vestibular neuronitis

76
Q

Episodic vertigo, n/v, fluctuating but progressive hearing loss, tinnitus, sensation of ear fullness

A

Meniere dz

Caused by intermitten increase in endolymphatic volume

77
Q

ear popping at time of sneezing, nose-blowing, coughing, straining followed by acute onset of vertigo

A

Perilymph fistula

78
Q

Vertigo precipitated by changes in position

A

Benign position paroxysmal vertigo (BPPV)
attacks usually last seconds-minutes
Caused by freely moving calcium carbonate crystals
Dix-Hallpike test - offending ear will be closest to the ground during the test

79
Q

Pt complains of an intermittant limp with foot tingling/numbness. On PE, impaired dorsiflexion and great toe extension. DTR’s intact

A

Common peroneal n.impingement
Associated with immobilization (cast), prolonged leg crossing, squatting
Dx w/ EMG, NCS
Tx - splinting, PT

80
Q

If you suspect Vit B12 deficiency, what else should be checked in addition to Sr B12?

A
Methylmalonic acid (MMA)
More sensitive in detecting B12 deficiency
81
Q

AMS + T>40C (105F)

A

Heat stroke

Complications include: rhabdo, ARF, ARDS, and coagulopathic bleeding

82
Q

How do you assess an elderly pt with gradual onset of forgetfulness

A

Neurocognitive testing
Will likely involve the mini-mental state exam
Differentiates between aging and dementia

83
Q

Most common causes of a single brain abscess

A

Staph aureus
Strep viridians
CT with ring enhancing lesion in a immunocompetent pt

84
Q

Brain CT/MRI reveals a butterfly appearing lesion with central necrosis

A

Glioblastoma multiforme

Shape is similar to the spinal cord

85
Q

Sudden onset unilateral orbitofrontal HA w/ n/v, unilateral eye pain w/ injected conjunctiva, dilated pupil w/ poor light response

A

angle closure glaucoma
Sudden narrowing of the anterior chamber angle
Asian woman >40
Can see aura’s. Sounds like a mix of migraine and cluster HA in stem

86
Q

Areflexic weakness in b/l UE and sensory loss in a cape like distribution

A

Syringomyelia
fluid-filled cavity w/in the cervical and thoracic spinal cord
Associated with chiari type 1

87
Q

Tx for Botulism

A

Equine antitoxin

Botulism toxin inhibits presynaptic ACh release

88
Q

What medications can cause idiopathic intracranial HTN (IIH)?

A

Growth hormone
Tetracyclines
Excessive vit A

89
Q

New onset seizure + LP with RBC’s and elevated protein

A

HSV encephalitis

Get a PCR of CSF

90
Q

Major complications after a SAH?

A

1st 24 hours - rebleeding
3-10 days - Vasospasm, vasonarrowing at the base of the brain due to degeneration of the vessels leads to infarction, dx with Ct angio and prevent with nimodipine

91
Q

Pathophys of tetanus

A

Disorder of the presynaptic neuromuscular junction
Clostridium tetani toxin
Blocks the release of inhibitory NT’s (glycine, and GABA)
Fever, muscle spasms (trismus)
Tx - debride, abx, IF against tetanus toxin, tetanus toxoid

92
Q

Tx of IIH?

A

Long term - Acetazolamid +/- furosemide

Acute - LP, steroids

93
Q

Vertical or horizontal gaze palsy

A

Progressive supranuclear palsy (PSP)

In the spectrum of a parkinsonian dz

94
Q

Startle myoclonus

A

CJD

95
Q

Tx for Tics

A

Antipsychotics

anti DA drugs

96
Q

Myasthenia gravis + ARF

A

Myasthenic crisis

97
Q

Where is the damage in cauda equina syndrome?

A

Spinal n. roots

Damage can happen b/l but assymetrically vs conus medullaris will be symmetric

98
Q

What side effects are expected soon after initiation of levodopa/carbidopa?

A

hallucinations, dizziness, HA, agitation

After many years - involuntary movements

99
Q

Sudden unilateral vision loss + fundoscopy exam with cherry red macula and retinal whitening

A

Central retinal a. occlusion
Mononuclear painless acute vision loss
Embolization from ICA or heart
Tx - manage underlying atherosclerosis or cardiac anomaly

100
Q

Rapidly progressing dementia + sharp wave changes on EEG

A

CJD

101
Q

MOA of benzo’s

A

Enhance GABA -> inhibitory influence on neurons

102
Q

Pt is unable to raise eyebrow, close the eye, facial drop, no nasolabial fold

A

Bell’s palsy

CN VII

103
Q

Left sided hemineglect is due to damage at the?

A

Right (non dominant) Parietal

104
Q

What do you do for people that have been in contact with a person that had bacterial meningitis?

A

Abx prophylaxis

105
Q

Teenager frequently falls asleep in class and has episodes of neck/knee muscles when socializing

A

Narcolepsy

Episodes are likely cateplexy

106
Q

What is useful in dx’ing if a pt has acute angle gluacoma?

A

Tonometry

Measures intraocular pressure

107
Q

Pt has exercise intolerance (muscle pain, fatigue, cramps) and has redish urine shortly after

A

McArdle Dz (Muscle phosphorylase deficiency)
Defect in glycogen storage
Myoglobinuria shortly after exercise (due to rhabdo)
“Second wind” phenomenon

108
Q

Quickest way to decrease intracerebral pressure?

A

Intubation and hyperventialtion
Can give IV mannitol once stable
Decrease in CO2 -> vasoconstriciton

109
Q

Syncopal episodes, sig decreased BP in one arm

A

Subclavian steal syndrome

Decreased brain stem perfusion due to reversal of flow in one vertebral artery

110
Q

Increased cholinergic activity is caused by?

A

Organophosphate activity

111
Q

Tx for Restless leg syndrome

A

Pramipexole

112
Q

Pt has vomiting/diarrhea, tinnitus, + rash (erythematous patches, hyperpigmented macules, depigmented macules, nails with white lines), decreased sensation absent ankle reflexes

A

Arsenic poisoning

113
Q

Most common cause of movement disorders?

A

Metoclopramide (used to treat gastroparesis)

Can cause neuroleptic malignant syndrome

114
Q

Pt does not meet all the criteria of SIGE CAPS but has had depressed mood x 3 years

A

Dysthymia
Chronic depression that persists for at lease two years
Less acute and severe than MDD

115
Q

Atrophic gastritis pt has LMN and UMN signs

A

Vit B12 deficiency

116
Q

Pt has a stroke syx x 4hrs + vegetations on heart valve. How do you manage?

A

Blood cultures and abx

117
Q

Osteoblastic bone met most likely came from

A

Prostate

118
Q

Osteolytic bone met most likely came from

A

Lung

119
Q

Unilateral decrease in hearing

Turning fork over forehead lateralizes to the NL ear

A

Neurofibromatosis

Sensorineural hearing loss

120
Q

Kid w/ seizures, suprasellar mass with specs of calcium

A

Craniopharyngioma

121
Q

Temporary (hours) total disruption of short term memory

A

Transient global amnesia

Don’t need to do anything unless it is recurrent

122
Q

Initial Tx for Shingles

A

po Acyclovir

123
Q

Degeneration of striatal GABA neurons

A

Huntington’s Dz

Atrophy of caudate on CT

124
Q

Sinus infection leading to diplopia, partial loss of vision in one eye

A

Cavernous sinus thrombosis

125
Q

1RF for Stroke

A

HTN

126
Q

Best management for a solitary brain met?

A

Surgical resection

Multiple - radiation

127
Q

Following trauma:
Decreased motor, pain, and temp fxn b/l
Proprioception, vibration, light touch intact

A

Anterior cord syndome
Caused by damage to the anterior spinal artery
Vibration, proprioception, and light touch are fed by dorsal column arteries

128
Q

At what point during a seizure is a pt at risk of hypoxic injury?

A

Status elepticus lasting >5min

129
Q

Young adult presents with tremor, muscular rigidity, clumsy gait + liver dz. how do you confirm dx?

A

Slit lamp (kayser-Fleischer rings) + Low Serum ceruloplasmin level
Wilsons dz
ar, abn copper deposition

130
Q

Hemorrhagic stroke with occipital HA, nuchal rigidity, n/v, nystagmus, ipsi hemiataxia

A

Cerebellar hemorrhage
Confirm with CT
Get emergency surgical decompression

131
Q

How do you manage a pt that hasn’t had breakthrough seizures in > 2 years on phenytoin but contemplating pregnancy

A
Slowly taper and d/c phenytoin
Known tertogen (fetal hydantoin syndrome)
Slowly taper to prevent chance of withdrawl seizure
132
Q

Ppx tx for pt w/ frequent migraines

A

Topiramate
Divalproex sodium
TCA’s
Beta blockers

133
Q

Following a trauma, Head HT reveals numerous punctuate hemorrhages w/ blurring of the gray-white matter interface

A

Diffuse axonal injury (TBI)
Caused by sudden accelration-deceleration impact
Can cause LOC -> vegetative state

134
Q

How do you work up a pt with transient (<10m) painless monocular vision loss? “Curtain falling over the R eye”

A

Duplex u/s of the carotids
Suspicious for amaurosis fugax
Retinal ischemia due to atherosclerotic emboli from the ipsi carotid a.

135
Q

Band like HA around temporal and occipatal lobes

A

Tension type HA
Tx - NSAIDS
If persistent/frequent - TCA’s

136
Q

Decreased sensation over thumb and index finger suggests damage to which nerve root?

A

C6

137
Q

Post MVA pt is comatose, has CN III palsy, and is hyperventilating. This is concerning for?

A

Uncal herniation

Can compress CN 3 and midbrain compression -> decerebrate and coma

138
Q

What CSF finding is diagnostic for CJD?

A

Increased 14-3-3 protein

139
Q

Brain MRI reveals abn T2 signal in basal ganglia

A

CJD

140
Q

Left honomynous hemyanopsia
Left sided neglect
Speech intact

A

R PCA

141
Q

Lambort-Eaton involves pre-synaptic Ab attack at the?

A

Myoneural junction

142
Q

Following administration of haloperidol pt has reptitive neck extension and uncontrollable eye movements. Tx?

A

Give Anticholinergic

she is having dystonias in response to the antipsychotic

143
Q

How do you manage a pt with syx of temporal arteritis and new onset of dim vision in one eye

A

Corticosteroid therapy now and temporal artery biopsy within 3 days
This helps to prevent blindness

144
Q

Initial workup for a pt with difficulty using hand

A

Electrophysiology studies

145
Q

Homebrewer has 2 wk hx of progressive weakness, no UMN signs, microcytic anemia and hyperuricemia

A

Lead poisoning

146
Q

Progressive visual dimming in the eye x hours + Decreased acuity + NL CT

A

Optic neuritis

147
Q

Child w/ hx of strep infection presents with involuntary movements and OCD

A

PANDAS

Autoimmune disorder of the basal ganglia

148
Q

Child w/ hx of strep infection presents with involuntary movements, emotional liability, and hypotonia

A

Sydenham Chorea

149
Q

Progressive muscle weaknees + elevated EST + elevated creatinine kinase

A

Polymyositis

Dx with an EMG

150
Q

DM pt is presenting w/ neuropathic pain and some numbness after taking a course of steroids

A

Diabetic Neuropathy

Exacerbation due to steroid use (hyperglycemia)

151
Q

Immediate tx for a spinal tumor causing mass effect

A
IV dexamethasone (steroids)
Future - surgical resection
152
Q

Younger male with back pain that is most severe when waking. Tenderness over insertion of the Achilles

A

Ankylosing spondylitis

153
Q

Epileptic pt has superior quadrant honomynous hemianopsia. Where is the lesion?

A

Temporal lobe

Look for complex (LOC) partial (not full body) seizure

154
Q

Tx for narcolepsy

A

Modanfinil

155
Q

College student presents with seizure after drinking a lot of water at a party. Hyponatremic, Elevated Cr kinase

A

Ecstasy OD

156
Q

Neurofibromatosis type 1 is associated with

A

Nodules on the lips and tongue
Cafe au lait spots
Optic nerve glioma

157
Q

NF type II is associated with?

A

B/l acoustic Schwanomas

158
Q

Tx for TIA

A

Start Aspirin, statin

Modify RF’s to improve BP control

159
Q

PD pt presents with acute angle-closure glaucoma. Why?

A

Trihexyphenidyl (anticholinergic used in PD)

160
Q

Elderly pt w/ spondylosis presents w/ weakness that is more pronounced in the UE than the LE following a trauma

A

Central cord syndrome
Occurs w/ hyperextension injury in a elderly pt with pre-existing deenerative changes
Damage to the lateral spinothalamic tract

161
Q

pt has sudden burst of flashing lights, blurred vision. Opthalmoscope reveals retinal tears and grayish appearing retina

A

Retinal detachment
Sudden onset of photopsia and floaters
“Curtain coming down over my eyes”

162
Q

Fundoscopy reveals “blood and thunder” appearance of optic disk swelling, retinal hemorrhages, dilated veins, cotton wool spots

A

Central retinal vein occlusion
painless loss of vision\
if the thrombi comes from the ICA = amaurosis fugax, tends to be more temporary

163
Q

Pain and swelling over inner aspect of the eye, pressure causes expression of purulent discharge

A

Dacrocystitis
Infection of the lacrimal sac caused by staph or strep
Infants and adults>40
Tx - systemic abx

164
Q

Pt with progressive vision loss is asked to cover his left eye and look at a small spot on a grid and describes the vertical lines as bent and wavy. Why?

A

Macular degeneration
Most common cause of blindness in industrial countries
Lose fine visual acuity first

165
Q

Corneal vescles and dendritic ulcers

A

Herpes simplex keratitis
Frequent cause of corneal blindness
Tx - top or po Antiviral

166
Q

Painful slwelling of the eyelid with no changes of the eye itself

A

External hordeolum (stye)
inflammatory disorder of the eyelash follicle or tear gland
Tx - warm compress
Can have a residual painless nodule that resolves within months after (Chalazion)

167
Q

Parkinsonism + orthostatic hypotension, impotence

A

Shy-Dager (Multiple system atrophy)

Tx- Intervascular volume expansion

168
Q

Loss of pain/temp over ipsi face, contra body
Vertigo, nystagmus
Horner’s

A

Lateral medullary infarct (wallenbery)
Motor fxn is spared
Occlusion of vertebral a.

169
Q

CNVII defect that is below the pons

A

Bell’s palsy, pt can’t close eye or lift eyebrows

Above the pons will spare the forehead (Facial n. palsy)

170
Q

Pramipexole (RLS tx) alters?

A

DA agonist

171
Q

CSF finding in Guillain Barre?

A

Elevated protein
NL cell count
(albuminocytologic dissociation)

172
Q

Broca’s aphasia is caused by a lesion in?

A

Dominant frontal lobe
Spares, nonfluent speech
Associated with Right face and UE hemiparesis

173
Q

What can happen if pseudotumor cerebri is left untreated?

A

Blindness