OB first trimester abnormalities registry review Flashcards
Ectopic pregnancy
A pregnancy located anywhere other than the central uterine cavity
Most common cause of pelvic pain with positive pregnancy test
Ectopic pregnancy
Most common location of ectopic pregnancy
Ampulla of fallopian tube
Most dangerous location of ectopic pregnancy
Interstitial/corneal because of rupture and hemorrhage
Heterotopic pregnancy
IUP and coexisting ectopic. Rare. Most often associated with assisted reproduction. Risk: hx PID, endometriosis, previous ectopic
hCG level 1,000-2,000 with no IUP
Suspect ectopic
Clinical presentation of ectopic pregnancy
-Pain, bleeding, palpable mass
-Lower than expected hCG, low hematocrit, shoulder pain
Sonographic appearance of ectopic pregnancy
-Extrauterine GS “live” pregnancy
-Complex adnexal mass or adnexal ring sign
-Free or complex fluid in pelvis
-Pseudogestational sac
-Poor decidual reaction in endo
Gestational trophoblastic disease (molar pregnancy)
Abnormal combination of male and female gametes resulting in rapid proliferation of trophoblastic cells
Trophoblastic hCG production in molar pregnancy
Excessive levels of hCG or rapidly rising levels; placenta grows out of control, takes over, undergoes degeneration becoming complex with cystic changes
Complete hydatidiform mole
Absence of fetus or gestational sac. Benign with malignant potential, clear defined boarders contained within myometrium
Partial hydatidiform mole
Coexisting IUP/GS and possibly fetus. Minimal malignant potential
Most common gestational trophoblastic disease
Complete hydatidiform mole
Invasive molar (chorioadenoma destruens)
Molar pregnancy that becomes malignant and invades into myometrium through uterine wall and into peritoneum
Choriocarcinoma
Most malignant progressive form with possible mets to lung (most common), liver, brain
Clinical presentation of molar pregnancy
Hyperemesis, markedly elevated hCG, bleeding, enlarged uterus, hypertension
Sonographic appearance of molar pregnancy
Large complex mass within uterus, multiple cystic areas throughout, loss of myometrium or boarders if invasive, bilateral theca lutein cyst
Non progressive pregnancies/miscarriages
Either hCG or sonographic appearances do not match what is expected. LMP not reliable, base of hCG + sono or sono alone
Low hCG or S<D
-Incorrect dating
-Ectopic
-Non progressive/failed pregnancy
High hCG or S>D
-Incorrect dating
-Multiple gestations
-Gestational trophoblastic disease (molar pregnancy)