OA and OCD Flashcards
What function/purpose do synovial joints serve?
permit motion while providing stability
for load transfer between bones
hip, stifle, elbow, shoulder
What type of DJD (non/-inflammatory) is Osteoarthritis/Osteoarthrosis?
non-inflammatory DJD
Explain the general pathology of OA…
within the joint,
the articular cartilage is degenerating
—> bone hypertrophy (osteophytes/-osis)
—> synovial membrane changes
How are Rheumatoid Arthritis and Feline Chronic Progressive Polyarthritis classified as an arthropathy?
inflammatory
Noninfectious
EROSIVE
How are Immune-Mediated Polyarthritis,
Chronic Inflammatory-induced Polyarthritis,
and Systemic Lupus Erythematosus
classified as arthropathies?
- *inflammatory**
- noninfectious*
- *NONEROSIVE**
What are we looking for in a physical exam on joints?
CREPI
Crepitus
ROM
Effusion
Pain
Instability
What breeds are predisposed to OA?
labs,
GSDs
What % of OA dogs are 8-13 years old?
50%
45% of OA dogs are ____ breeds.
large
A cat is showing reluctance to jump, climb stairs, and groom. What is the most appropriate descriptive diagnosis for this cat?
moderate OA
*in dogs,
pain/muscle atrophy/and difficulty rising
are classified as moderate OA
T or F:
Bone Scintigraphy is used to diagnose OA.
FALSE
it’s used to localize the source of lameness
it will light up in areas of inflammation, tumors, anything…
What type of cells would we see on fluid analysis from a dog with DJD?
mononuclear cells
_vs_. Inflammatory arthropathies: neutrophils
How does the new drug Galliprant work?
Targets the inflammatory prostaglandins
so it has less GI and kidney s/e
Why are corticosteroids NOT recommended in treating DJD?
because they depress chondrocyte metabolism
and they alter the extracellular matrix
—>results in: lower proteoglycan & collagen synthesis
within the ECM
Osteochondrosis is a disturbance in the process of __________ __________ that leads to ___________ ________/_______.
endochondral ossification;
cartilage retention/thickening
Why is cartilage thickening a problem in Osteochondrosis (on a cellular level)?
increased cartilage thickness
can result in malnourished, necrotic chondrocytes
chondrocyte nutrition comes from synovial fluid -
if they cant get that fluid within the cartilage because its so thick,
they become malnourished and can become necrotic…
In shoulder joint osteochondrosis, early detection may involve what finding upon lateral radiograph of the shoulder?
Flattening of the subchondral bone
of caudal humeral head
In shoulder joint osteochondrosis, later detection may involve what finding upon lateral radiograph of the shoulder?
Saucer shaped radiolucent area
A patient suffering from shoulder joint osteochondrosis maybe exhibit pain to what actions of the shoulder?
Flexion
& hyperextension
What are the 3 mandatory indications for treating shoulder OCD by conservative management?
- Small defect
- Minimal to no lameness
- Very young dog (<6mo)
rest, diet (Ca, vitD), NSAIDs
Where do we typically see elbow joint OCD?
Distal aspect of medial humeral condyle
(we might see a radiolucent concavity here on rads)
What actions are expected to elicit pain in a patient with elbow joint OCD?
Elbow extension
& lateral rotation of forearm
What would we likely see on radiograph of a patient with stifle joint OCD?
radiolucent concavity on medial aspect of lateral femoral condyle
medial condyle can also be affected…
Tarsus OCD is most common in what breeds?
Large - rotties esp!
A patient with tarsus OCD might elicit pain to what action?
hock flexion
What might we find radiographically in a patient with tarsus OCD?
radiolucent concavity on medial (or lateral)
trochlear ridge of talus
Rank the 4 joints in order of best prognosis with OCD to worst.
shoulder > stifle > elbow > tarsus
