NV,D,C,IBS,GERD/PUD Flashcards
antihistamine options for NV
dimenhydrinate
diphenhydramine
meclizine
doxylamine
scopolamine
hydroxyzine
generic for Bonine
meclizine
generic for Unisom
doxylamine
generic for dramamine
dimenhydrinate
phenothiazines used for NV
promethazine
prochlorperazine
generic name for phenergan
promethazine
genetic name for compazine
prochlorperazine
side effects of phenothiazines
hypotension, QTcP, EPS
BBW for phenergan (promethazine)
tissue damage – DO NOT GIVE IV
main 5-HT3 antagonist used for NV
ondansetron (zofran)
side effects of zofran
constipation, headache, QTcP
prokinetics used for NV
metoclopramide
erythromycin
generic for reglan
metoclopramide
side effects of Reglan
EPS, QTcP, diarrhea
side effects of erythromycin
NV, diarrhea, QTcP
corticosteroid used for NV
dexamethasone
1st and 2nd line for general NV
- 5HT3 > metoclopramide
- phenothiazine
first line for disorders of balance
antihistamines
1st and 2nd line for NV of pregnancy
- antihistamines + B6
(doxylamine/Unisom + B6)
Diclegis or Bonjesta if OTC do not work - 5-HT3 > metoclopramide
1st and 2nd line for gastroparesis
- metoclopramide
- erythromycin
Apfel Criteria for post-op NV (4)
female
nonsmoker
hx of motion sickness or PONV
planned used of post-op opioids
what treatment is used for PONV if score 4 (high risk)
scopolamine patch 2 hours before anesthesia
IV dexamethasone after anesthesia
5HT3 at end of surgery
treatment for moderate risk PONV (score 2-3)
5HT3 at end of surgery
treatment for low risk PONV (score 0-1)
no planned therapy
rescue therapy for PONV
5HT3 antagonist or drug from another class
general approach of treatment for acute constipation
osmotic, sitmulant
general approach of treatment for chronic constipation
- bulk forming
- osmotic/stimulant
therapies used for chronic idiopathic constipation
lubiprostone
linaclotide
plecanatide
generic for amitiza
lubiprostone
generic for linzess
linaclotide
generic for trulance
plecanatide
side effects of lubiprostone
diarrhea and nausea