Hyperlipidemia Flashcards

1
Q

statin CI

A

active liver disease
unexplained elevated AST or ALT x3 ULN
Pregnant or nursing women
major DDIs

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2
Q

statins metabolized by CYP3A4

A

lovastatin > simvastatin > atorvastatin

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2
Q

statin AEs

A

diarrhea, arthralgia, nasopharyngitis, myalgia

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2
Q

hydrophilic statins

A

pravastatin and rosuvastatin

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3
Q

long 1/2 life statins

A

atorvastatin > rosuvastatin > pitavastatin

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4
Q

atorvastatin high intensity dose

A

40-80

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5
Q

rosuvastatin high intensity dose

A

20-40

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6
Q

atorvastatin moderate intensity dose

A

10-20

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7
Q

rosuvastatin moderate intensity dose

A

5-10

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8
Q

simvastatin moderate intensity dose

A

20-40

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9
Q

pravastatin moderate intensity dose

A

40-80

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10
Q

lovastatin moderate intensity dose

A

40

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11
Q

fluvastatin moderate intensity dose

A

80

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12
Q

pitavastatin moderate intensity dose

A

2-4

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13
Q

simvastatin low intensity dose

A

10

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14
Q

pravastatin low intensity dose

A

10-20

15
Q

lovastatin low intensity dose

A

20

16
Q

fluvastatin low intensity dose

A

20-40

17
Q

pitavastatin low intensity dose

A

1

18
Q
A