Nutritional Supplements Flashcards

1
Q

5 nutritional supplements:

A
  • creatine
  • branched chain amino acids (BCAA)
  • beta-hydroxy beta-methylbutyrate (HMbeta)
  • buffers (bicarbonate, beta-alanine)
  • caffeine
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2
Q

Creatine name:

A

alpha-methyl guanidine-acetic acid

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3
Q

Creatine is a natural substance found in the human body in:

A
  • free form (creatine, Cr, 60-70%)

- phosphorylated form (phosphorylcreatine, PCr, 30-40%)

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4
Q

Both forms of creatine are ____ and ____ degraded into creatinine.

A
  • spontaneously

- irreversibly

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5
Q

Creatine is excreted via the ____ with the _____.

A
  • kidneys

- urine

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6
Q

Rate of creatine:

A

~2 g/d (~1.6% of total body stores)

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7
Q

Creatine is synthesized endogeneously by:

A
  • arginine
  • glycine
  • methionine
  • ~1-2 g/d
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8
Q

Ceatine can be consumed in the diet mainly from:

A
  • meats
  • fish
  • dairy
  • ~1-5 g/d
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9
Q

The amount of Cr in the human body varies depending on individual’s ___ ____.

A

muscle mass

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10
Q

Approximately ___% of the creatine content is found in ____ _____.

A
  • 95%

- skeletal muscle

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11
Q

A small portion of Cr can also be found in the….

A
  • brain
  • bone
  • testicles
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12
Q

Cr plays an important role in ____ ____ ____ during muscle contractions, specifically involving ____ , ____ ____, _____ ____.

A
  • rapid energy provision
  • high intensity
  • short duration
  • interval training
  • ADP + PCr + Hplus = ATP + Cr
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13
Q

The transfer of ______ group from PCr to ADP regenerates ATP through a reversible reaction catalyzed by the enzyme ____ ____ .

A
  • N-phosphoryl

- creatine kinase (CK)

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14
Q

Cr supplementation improves performance (___%) of ____ intensity, ____ duration (< ___) and, in particular, ____ activities that depend on the ___ system.

A
  • ~10-20%
  • high
  • short
  • < 30 s
  • interval
  • ATP-PCr
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15
Q

Cr improves performance for:

A
  • cycling
  • pole vault
  • sprint running
  • speed skating
  • short distance swimming
  • jumping
  • bicycle ergometry
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16
Q

Potential ergogenic benefits of Cr supplementation:

A
  • inc. single and repetitive sprint performance
  • inc. work performed during sets of max effort muscle contractions
  • inc. muscle mass and strength adaptations during training
  • enhanced glycogen synthesis
  • inc. anaerobic threshold
  • possible enhancement of aerobic capacity
  • inc. work capacity
  • enhanced recovery
  • greater training tolerance
17
Q

In the short term (< 7 days) lean mass gain is related to ____ ____.

A

water retention (intracellular)

18
Q

Cr is an ______ active substance.

A

osmotically

19
Q

Lean mass gain is expected after ___ weeks of Cr supplementation when combined with ____.

A
  • ~4 weeks

- RE

20
Q

What happens to body comp if Cr is ingested and no exercise training is performed?

A

no changes in lean mass, muscle function, or bone health

21
Q

There are mainly 3 Cr supplementation protocols:

A
  • loading
  • maintenance
  • loading + maintenance
22
Q

Loading Cr:

A
  • 20-30 g/day for 5-7 days

- muscle is saturated after 5-7 days

23
Q

Maintenance Cr:

A
  • 5 g/d

- muscle is saturated after 4 weeks

24
Q

Loading + maintenance Cr:

A
  • 20-30 g/day for 5-7 days + 5 g/d from day 8 on

- muscle is saturated after 5-7 days and content is maintained after that

25
Q

Best form of Cr:

A
  • creatine monohydrate

- intestinal absorption ~100%

26
Q

Factors that can optimize Cr muscle uptake:

A
  • previous exercise

- carb ingestion (high GI)

27
Q

Side effects of Cr:

A

no side effects induced by 12 weeks of creatine supplementation in older adults

28
Q

The branched chain AA are 3 of the ___ EAAs.

A

9

29
Q

BCAA ____ be produced by the body in physiologically significant amounts.

A

cannot

30
Q

BCAAs are precursors for ____ ____ ____.

A

muscle protein synthesis

31
Q

Widely believed claim that consumption of BCAAs:

A
  • stimulates muscle protein synthesis

- improves endurance performance (central fatigue hypothesis)