nutrition in dev of oral tissues Flashcards
Function of Food (Nutrients)
provide energy source of body work, provide structural component, and maintenance of oral tissues. Regulate metabolic processes, maintain a constant internal environment
Provide energy source of body work
– Energy is stored as ATP in cells, glycogen in liver, fat in
adipose tissue.
– Mainly from carbohydrate and fat.
Provide structural components for growth,
development, and maintenance of oral tissues
– Mainly from protein (collagen), minerals (calcium and
phosphorus), fat, water.
Regulate metabolic processes
– Carbohydrate, protein, fat, vitamins, minerals, water
Maintain a constant internal environment
– By controlling the fluid balance & temperature.
– Mainly from water, protein, fat, mineral
Nutrition
– Is the intake of nutrients such as proteins, fats and
carbohydrates, vitamins, essential minerals and
trace elements for development, growth, repair
and maintenance.
• Diet
– Amount & type of food consumed to meet specific
requirements of individual.
Macronutrients
• Nutrients required by the body in large amounts (gram) – Carbohydrates – Proteins – Fats
Micronutrients
Nutrients required by the body in small amounts – Vitamins – minerals
The Importance of Nutrients in the Oral
Cavity
- Development & growth of oral tissues
2. The continued maintenance of oral tissues
During the development & growth of oral
tissues
– Nutrient requirement during this phase is
influence by systemic factor
– Defects/abnormalities acquired during this stage
– Defects/abnormalities acquired during this stage
• is highly influenced by the nutrients supply in the
mother’s blood
• is also contributed by genetic factors
– eg. Amelogenesis imperfecta
Nutrient requirement during this phase is
influence by systemic factor
• during prenatal development, nutrients are obtained
from the mother’s blood
Any interferences occurred during growth
development could lead to :
hypoplasia
hypoplasia
Disturbances of ameloblasts activity which will affect the
function of the ameloblasts and lead to disturbances during
the mineralisation stage
cause of hyppoplasia
» Hypoplasia chronological – caused by prolonged fever
(measles)
» Colorado stain/Fluorosis (opaque enamel)
• caused by exposure to high fluoride level during
mineralisation phase
Hypoplasia chronological
Hypoplasia chronological
Colorado stain/Fluorosis (opaque enamel)
Colorado stain/Fluorosis (opaque enamel)
During the continued maintenance of oral
tissues
Nutrient requirement during this phase is
influence by environmental factors
Nutrient requirement during this phase is
influence by environmental factors
• interaction between oral tissues & environment
components within the oral cavity
• eg. Caries, Gingivitis, Periodontal diseases
protein fx
- Source of amino acids for protein
synthesis in tissues development - Synthesis of protein conjugates
- Structural components & regeneration of the tissues
- Protection by synthesizing defense proteins
- Regulates the metabolism process
- Transporter & binding protein
- Regulates the pH in saliva
- As an energy production (insufficient of carbohydrate)
- Source of amino acids for protein
synthesis in tissues development
animal protein, plant protein
animal protein
• Rich in essential a/a • Must be obtained from diet • Cannot synthesized by human e.g. Phe, Leu, Val, Met, His, Arg, etc • More desirable than plant
– Plant proteins
Deficient in some a/a
• e.g. Trp, Lys & Sulfur-containing a/a
• but may contain other a/a in excess
- Synthesis of protein conjugates
– Amylases
– Glycoproteins: Mucin
- • Structural components & regeneration of the tissues. pro
Collagen: matrix protein of dentin, cementum, bones & PDL.
- Protection by synthesizing defense proteins
– IgA: neutralize the foreign substance
– Histatins: salivary antifungal proteins
- Regulates the metabolism process.. pro
Calmodulin regulates the calcium-mediated process
- Calmodulin regulates the calcium-mediated process.. pro
– Hemoglobin: oxygen transport
– Albumin: major protein transporter
- Regulates the pH in saliva.. pro
– Sialin: salivary pH buffering protein
- As an energy production (insufficient of carbohydrate)
– Protein is metabolised to be used for energy.
Protein digestion
Plant protein is poorly digestibility
Plant protein is poorly digestibility due to
Presence of peptide bonds which are resistant to
digestive enzymes
– Presence of enzyme inhibitors e.g. trypsin inhibitor
– Presence of fibres which hinders the access of
proteolytic enzymes
• Deficiency of protein
– Defects in teeth composition, eruption pattern &
resistance to decay
– Increase susceptibility to infection in soft tissues
– Poor healing & tissue regeneration
fx carb
as source and storage of energy, main constituent of connective tissues, combines with protein to form glycoprotein, dietary sources
(cho) As source & storage of energy
– Most of the process needs ATP to be
function
– Store in liver & muscle as glycogen
(cho) main constituent of connective tissues
glycosaminoglycan
cho : Combines with protein to form
glycoprotein.
mucin
dietary sources of cho
– Starch & fibres (Polysaccharide)
– Sucrose (Disaccharide): Cariogenic
– Glucose, fructose, lactose
(Monosaccharide)
fx fibres
Is the supporting structures of plant cell
walls.
Retains H2O & binds acidic materials &
metals by its cation exchange capacity
fibre eg supporting structure
cellulose, hemicellulose, pectin substances,
lignin
digestibility
-Cannot be digested by mammalian enzymes
– But extensive degradation may occur as a
result of microbial action in the colon
The main products of the anaerobic
fermentation of fibre:
• Volatile fatty acids (acetate, propianate, butyrate) • Gas (CO2 , H2 , methane) • Energy
Physiological effects of dietary fibre in the
mouth:
– Fibre rich food require more mastication – thus
lead to reduction of food eaten – help in control of
obesity
– Chewing promotes a greater flow of saliva –
prevent stagnation of food – reduce dental caries
lipid fx
Major source of energy after
carbohydrate.
• Facilitates lipid-soluble vitamin absorption.
• Precursor for cholesterol synthesis
• Provides EFAs (linolenic acid & linoleic
acid
-Some lipids essential for calcification.
lipid as precursor for cholestrol
– Cholesterol is the precursor for vitamin D &
steroid hormones synthesis
EFAs
important for synthesis of lipid
molecules (DHA/EPA) in the body
• Some lipids essential for calcification.
Associated vit D: vit D is essential for
mineralization of hard tissues.
excess lipid
stored in adipose tissue and is
burnt when the body has run out of
carbohydrates.
Vitamins
Organic compounds; contain carbon & nitrogen
vit can be classified as
– lipid-soluble (vit A, D, E & K)
– water-soluble (vit B & C)
general fx of vit
– Essential for normal metabolism, growth and development
and regulation of cell function.
– As coenzyme in energy & protein synthesis
deficiency of vits
affects the oral tissues
excess of vit
– Water-soluble: readily excreted to the urine
– Lipid-soluble: accumulated in liver & fatty tissues in the
body (harmful)