Nutrition Final Flashcards
Prions are also known as?
TSE (Transmissible spongiform encephalopathies)
What is the normal form of prion called?
PrP c (Cellular)
What is the infectious form of prions?
PrP sc (scrapie)
PrP sc interacts with PrP c and changes to what?
PrP sc
Which prion disease affects sheep?
Scrapie
What are the other names for Scrapie?
Cuddy trot (Scotland)
Rubbers or the googles (England)
Le treblante or the trembles (France)
Bovine spongiform encephalopathy (BSE) aka:
Mad cow disease
What causes abnormal motor nerve control an aggressiveness?
BSE
Prion disease seen in mule deer, elk, white and black tailed deer
CWD (Chronic Wasting Disease)
What sheep breed are more prone to Scrapie?
Black face sheep
How is scrapie passed?
Ewe to offspring
Disease spread by force feeding infected cadavers, inferior quality meat, and slaughterhouse scraps.
BSE
Heating prions to ____ renders them inactive
130 degrees C
PrP CWD live in environment for ____ years
2 years
How is TME transmitted?
eating contaminated feed
How is FSE transmitted?
Eating BSE contaminated meat
When prions form together they form large aggregates called _____
Amyloid
Where do prions typically kill and damage brain cells?
Cerebellum or cerebral hemispheres
How is scrapie diagnosed?
clinical signs and biopsy of lymphoid tissues on inside of third eyelid
How is BSE diagnosed?
ELISA, immunassay
What is the causitive agent of cat scratch fever?
Bacteria bartonella henselae
Higher rates of cat scratch fever are reported when?
Autumn and Winter
Children make up for ___% of cat scratch fever infections
80%