Exam 2 Flashcards
An animate or inanimate object that serves as a long term habitat and focus of dissemination for an infectious agent
Reservoir
An individual or object from which an infection is actually acquired
Source of infection
Reservoir for Cryptosporidium parvum
Cattle
Source of infection for crypto parvum
Water
Exampe of a case where the reservoir and source are the same
Syphilis (humans are reservoir and source)
Objects that are able to transfer disease organisms
Fomite
Any live animal that transmits an infectious agent from one host to the next. Typically used to describe arthropod reservoirs
Vector
Vector type that actively participates in the pathogen’s life cycle
Biological vector
Vector type that is a passive participant in the transmission of disease
Mechanical
Spread of disease through a population from one infected individual to another (can be indirect or direct)
Horizontal Transmission
Spread of disease from parent to offspring via placenta, sperm, milk or ovum (always direct)
Vertical transmission
Example of direct contact transmission
Cat to human ringworm
Cat to human to cat is an example of what type of transmission?
Indirect contact transmission
A sneeze or a cough from infected to uninfected individuals is an example of what type of transmission?
Direct Airborne (aerosol) Transmission
A sneeze that contaminates a ventilation system that eventually infects animal/human is an example of what type of transmission?
Indirect Airborne (Aerosol) Transmission
Toxoplasma gondii and listeria monoctogenes are examples of diseases spread through which mode of transmission?
Placental
In placental transmission, the microbe can cross the placenta and enter the ____ ____ and spread disease
Umbilical vein
Placental transmission depends upon the ______ _____ and the ______ involved
Gestation stage and the microbe involved
Fomites spread disease through _______ transmission
Indirect
Bedding with E coli is an example of which type of transmission?
Fomites
Arthropods (vector transmission) spread disease through ______ transmission
Indirect
Disease classification that has severities and duration between acute and chronic. Accounts for some forms of anthrax.
Subacute Disease
Term for someone who studies the factors that determine the frequency and distribution of disease within populations
Epidemiologist
The number of new cases of disease in a defined population over a specific time period as compared to the general healthy population i a certain time period (typically over a year)
Incidence (morbidity rate)
Total number of cases in a population compared to the entire population
Prevalence
Formula for determining prevalence
Total number of cases in a population divided by the total number of individuals in a population X 100
Term for a disease always present within a population of a geographic area
Endemic disease
Disease affecting animals of specific geographic area. Constantly present in specific animal community but occurs in small number of cases
Enzootic disease
Term for disease with few isolated cases of disease in a widespread area in an unpredictable manner
Sporadic
Term for a sudden onset and widespread outbreak within a group
Epidemic disease
Term for a widespread disease in a population of animals other than humans. Spread rapidly, simultaneously affecting a large number of animals in a region
Epizootic disease
Term for a disease that is a widespread epidemic usually across continents
Pandemic Disease
Term for a widespread epizootic disease
Panzootic disease
United Nations organization for monitoring zoonoses
WHO (The World Health Organization)
What is the World Health Organization responsible for?
Promoting cooperation of health care among nations
Carry out disease control and eradication
Improve quality of human/animal life
This organization sends out teams of epidemiologists to investigate outbreaks and assist with bringing the outbreak under control
WHO
United States agency that functions to assist state and local health department in all aspects of epidemiology
CDC
Primary federal agency for conducting and supporting medical research
National Institutes of Health (NIH)
Line of defense that limits access to the internal tissues and organs of the body
First line of defense
What are the anatomic properties of the first line of defense?
Unbroken skin, Mucous membranes, Hairs and cilia
The second line of defense is composed of _______ and _______ protection
cellular and chemical
Fever stimulating chemical that could be bacteria, virus or parasites
Pyrogen
What are the benefits of Fevers?
Inhibit replication
Stimulate WBCs to destroy microbes, reduce iron available for bacterial replication
What are the disadvantages of fevers?
Increase HR, increased caloric demand, seizures, dehydration
Causitive agent of Anthrax
Bacillus anthracis
Non-motile, gram +, endospore forming bacilli
Conditions in which anthrax multiplies
60 degrees, heavy rainfall
Animals most commonly associated with the epizootic form of anthrax
Cattle, bison and deer (typically a disease of herbivores)
What are the three forms of anthrax?
Peracute, Acute and Chronic
Form of anthrax presenting with ataxia, dyspnea, trembling or sudden death. (Typically do not show any signs)
Peracute Anthrax
Form of anthrax in ruminants that produces localized edema, typically in the neck, thorax and shoulders.
Chronic anthrax
Form of anthrax causing lingual and pharyngeal edema and/or hemorrhage of the pharyndeal and cervical lymph nodes in swine
Chronic anthrax
Why should necropsies never be performed on animals suspected to have anthrax infection?
Spores form when exposed to oxygen
How are anthrax endospores destroyed?
Autoclaving, boiling for 30 minutes, expose to dry heat at 140 degrees for 3 hours, chemical disinfection at high concentration for a long period of time, cremation
Treatment for bite wounds
Clean, irrigate, debride, antibiotics (within 24 hours)
Disease also known as “Bang’s disease”, Contagious abortion, Matta Fever, or Mediterranean fever
Brucellosis
What species is resistant to Brucellosis?
Cats
Brucellosis in cattle is uncommon due to what in the US?
Vaccinations
Common transmission of Brucellosis to humans is from what species?
Sheep and goats
In what states is Brucellosis more prevalent?
Texas, California, Virginia and Florida
What are the mechanical vectors for Brucellosis?
Contaminated food, water and exretement
Ingestion of bacteria present in large animals in aborted fetuses and uterine discharges
Sexually transmitted fluids
Open wounds, conjunctiva or inhalation
Ingestion of contaminated milk
What is the pathogenesis of Brucellosis?
Brucella are engulfed by neutrophils and are carried in the lymphatic fluid to the lymph nodes, blood and organs
Clinical signs of Brucellosis
Spontaneous abortion, inability to conceive, inflammation of sex organs, death
What are methods of diagnosis of Brucellosis?
Gram stain
Culture
Serum Agglutination and ELISA
Treatment for Brucellosis?
Not attempted. Many recover from disease signs but infection remains. Infected animals are often eliminated.
How can Brucellosis be managed?
Vaccination and testing before breeding
What is the most common cause of acute infectious diarrhea?
Campylobacteriosis
Disease also known as vibriosis and vibrionic abortion
Campylobacteriosis