Nutrition and Metabolism Flashcards

1
Q

what is deamination?

A

Deamination is the removal of an amino group from a molecule

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2
Q

essential amino acids

A

histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine.

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3
Q

Two Essential Fatty Acids

A
  1. Linoleic (LA)= omega 6
    (Vegetable oil, sunflower oil, cottonseed oil)
  2. Alpha Linolenic (ALA)= omega 3
    Mustard seed oil, flax, walnut, fish and shellfish
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4
Q

Functions of glucagon

A
  1. glucagon promotes breakdown of glycogen to glucose (glycogenolysis),
  2. promotes glucose synthesis (gluconeogenesis),
  3. inhibits glycogen formation and thus mobilizes export of glucose into the circulation.
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5
Q

Functions of insulin

A
  • regulates glucose levels in the bloodstream

- induces glucose storage in the liver, muscles, and adipose tissue

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6
Q

-GLP 1

A

and serotonin make us feel full and satisfied

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7
Q

Glycogenesis

A

formation of glycogen when glucose supplies exceed cellular need for STP synthesis

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8
Q

glycogenolysis

A

breakdown of glycogen in response to low blood sugar

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9
Q

Glycolysis

A

breakdown of glucose into pyretic acid (1st step of cellular respiration before kreb cycle)

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10
Q

Ketogenesis

A

making of ketones by breaking down fatty acids and ketogenic amino acids

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11
Q

3 ketone bodies

A
  1. Acetoacetate
  2. Acetone
  3. Beta hydroxybutryate
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12
Q

Lipogenesis

A

excess dietary glucose and fatty acids are stored as triglycerides
-making fat

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13
Q

what organ synthesizes lipoproteins for transport of cholesterol and fats

A

liver

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14
Q

lipoproteins transport what?

A

cholesterol and fat

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15
Q

what hormone suppresses secretion of neuropeptide Y

A

leptin

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16
Q

causes cravings for carbs

A

neuropeptide Y

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17
Q

causes cravings for carbs

A

neuropeptide Y

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18
Q

enhance appetite

A

-orexins=

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19
Q

fat cravings

A

galanin=

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20
Q

3 events of protein metabolism

A
  1. transamination
  2. oxidative deamination (remove amino acid group)
  3. keto acid modification
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21
Q

deaminated amino acids are converted into

A
  1. pyruvic acid

2. one of the keto acid intermediates of the Krebs cycle

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22
Q

switching of an amine group from an amino acid

…to a keto acid [usually -ketoglutaric acid of the Krebs cycle]

A

transamination

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23
Q

___________ enhances facilitated diffusion of glucose into tissue

A

insulin

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24
Q

most abundant dietary lipids= _____________ (found in animal and plant foods)

A

triglycerides

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25
what function as coenzymes (especially B vitamins)
vigtamins
26
your body makes what vitmains
body makes D,K, and B
27
B12 needs_________ to be absorbed in ileum of small intestine
intrinsic factor
28
fat soluble vitamins
fat soluble= A, D, E, K
29
food broken down within the cells and some of the energy leads to ATP
cellular respiration
30
-anabolic=
growth, from small to large molecules
31
catabolic
breakdown from large to small
32
_________ shift the phosphate group of ATP to other molecules
-enzymes
33
added a phosphate group to something
phosphorylated=
34
________ and ________ rely almost entirely on glucose for energy
neurons and RBCs
35
extra glucose is converted to___________ or fat and stored
glycogen
36
need____ carbs/day
100g
37
4 Glucose Pathways
1. Glycolosis 2. Preparatory reaction 3. Citric acid (Krebs) cycle 4. Electron transport chain and oxidative phosphorylation
38
enzyme that synthesizes ATP
ATP synthesize
39
what creates a pH gradient and generates a voltage gradient
-electrochemical proton gradient
40
movement of hydrogen (H) across membrane
-chemiosmosis=
41
_____ fuel hepatocytes and skeletal muscle
fats
42
____ make up myelin sheath and cell membrane
-fats
43
-fat in adipose tissue provides
1. Protectors organs 2. Insulates skin 3. Storage for later energy use
44
what hormone is derived from fat, found in all tissues and organs, and synthesized from essential fatty acids
prostaglandin
45
Functions of prostaglandin’s
1. Smooth muscle contraction 2. Controls blood pressure 3. Inflammation
46
-most fats are transported in lymph as ____________
chylomicrons
47
2 Pathways of Fat Metabolism
1. Glycerol pathway | 2. Fatty acid pathway (beta oxidation)
48
which pathways is this: Glycerol converted into glyceraldehyde phosphate Then converted into CoA Acetyl CoA enters kern cycle
glycerol pathway
49
Undergo beta oxidation Leads to 2 carbon acid fragments which enter Kreb cycle Reduced coenzymes which enter the electron chain transport
fatty acid pathway
50
___________ necessary for oxidation of fat
oxaloacetic acid
51
________synthesizes lipoproteins for transport of cholesterol and fats
liver
52
what organ -synthesizes cholesterol for CoA
liver
53
structural basis of bile salts, steroid hormone, vitamin D
cholesterol
54
_____________ makes up part of hedgehog molecule that directs embryonic development
cholesterol
55
which cholesterol -transport excess cholesterol from peripheral tissue to the liver
HDL (protein dominated)
56
which cholesterol -transport cholestoel to peripheral tissue and regular cholesterol synthesis
LDL
57
which cholesterol -transport triglycerides to peripheral tissue
VLDL
58
-all or none rule (amino acids)
= all amino acids need to be present at the same time for protein synthesis to happen
59
amino acids must be_________ prior to oxidation for energy
deaminated
60
deaminated
amino group is removed from amino acid and converted into ammonia -deaminated amino acids converted into pyretic acid —> Kreb cycle
61
oxidative deamination
amine group of glutamic acid is released as amonia, combined with carbon dioxide, and peed out as urea