Nutrition Flashcards
Hormones of Digestive Tract
Gastrin-digests food, necessary for growth
Secretin-duodenum, stimulates stomach to produce enzymes/liver to produce bile, regulates water homeostasis
Cholecystokinin (CCK)-duodenum, causes pancreas to release enzymes, signals gallbladder, hunger suppressant
Body Mass Index (BMI)
body weight/height^2 Underweight: <18.5 Overweight: 25-29.9 Obesity: >30 Morbid Obesity: >35 w/comorbidities OR BMI >40 Waist M: >40in F: >35in
Obesity Assessment
H&P Fasting lipid profile TSH Fasting glucose &HgbA1C Liver enzymes
Risks for weightloss/malnutrition
9 D’s: dementia, depression, disease, dysphagia, disgeusia, diarrhea, drugs, dentition, dysfunction
Meals on wheels: medication effects, emotional probs, anorexia, late life paranoia, swallowing disorders, oral factors, no money, wandering/dementia, hyper/hypothyroidism, enteric probs, eating probs, low salt/cholesterol diet, social probs
Malnutrition
Need 2 or more:
-insufficient energy intake, weight loss, loss of muscle mass, loss of subcutaneous fat, localized/generalized fluid accumulation, diminished functional status (handgrip)
Anorexia
Decrease in appetite
Associated with poor emotional wellbeing, illness, drugs, dementia, mood disorder
Cachexia
Hypercatabolic state by accelerated loss of skeletal muscle due to inflammatory response involuntary weight loss more than 10% Anorexia Systemic inflammation Sarcopenia Fatigue Imbalance of catabolism and anabolism
Sarcopenia
Loss of skeletal muscle, strength, performance
Underlying illness doesn’t have to be present
Nutritional deficiency
Insulin resistance
Malnutrition Risk
At risk if 1+ met:
unintentional weight loss more than 10% in last 3 months
Body weight <90% ideal for height
BMI <18.5
Protein Deficiency
Hollowing of temporal muscles
Wasting of upper arms/thighs
Esily plucked hair
Peripheral edema
Screening Tools
Nutritional Risk Screening (NRS)
Simplified Nutrition Assessment Questionnaire (SNAQ)
SCREEN II
Malnutrition universal screening tool (MUST)
Mini nutritional assessment (MNA)
Malnutrition markers
- Mild: albumin 2.8-3.2, TS200-250, lymphocytes 1200-2000
- Moderate: Al 2.1-2.7, TS 100-200, lympho 800-1200
- Severe alb <2.1 TS<100 Lympho<800
Treatment for Weightloss
Treat underlying condition
Address inadequate food intake
Fat soluble vitamins
A, D, E, K
More toxic than water soluble in excess
Vitamin A
Retinol
Bile needed for absorption, stored in liver
Helps bone/tooth, skin/mucous membranes, dim light vision
Deficiency: night blindness, dry eyes, goose bump rash
Excess: liver damage/increased pressure on brain, vision changes, bone pain, rough skin/dry lips
Sources: Dark leafy green/yellow veggies, fortified dairy, liver
Vitamin D
Calcium hemostasis/bone metabolism/internal Ca/K absorption
Inhibited by glucocorticoids
Deficiency: Rickets, osteomalacia
Excess: anorexia, n/v, polydipsia, polyuria
Sources: fortified milk, fish liver oil, UV exposure, supplements
Recommended dose: 600IU/day
Best lab: serum 25-hydroxyvitamin D
Vitamin E
AKA Tocopherols
Vision, reproduction, health of blood/brain/skin, cell membrane protection
Deficiency: neuropathy, RBC hemolysis in malnourished infants
Excess: ow toxicity, augments anticoagulant effects
Sources: salad oil, shortenings, margarine, whole grain, legumes, nuts, dark leafy veggies
RDA: 15mg/day
Vitamin K
Forms PT, synthesized in intestines, neg. effected by antibiotics
Deficiency: prolonged clotting time, heme (esp in newborns)
Excess: toxic in large amounts
Sources: intestinal bacteria, dark leafy veggies
Vitamin C
Forms collagen, hormone synthesis, teeth firm in gums, infection resistance, iron absorption
Deficiency:poor wound healing, poor bone/tooth development, dry skin, petechiae, fatigue, scurvy
Excess: kidney stones, false neg urinary glucose in DM
Sources: citrus, strawberries, cantaloupe, tomatoes, broccoli, raw green veggies, potatoes, peppers
Vitami B1-Thiamine
Coenzyme for glucose breakdown, healthy nerves, good digestion, normal appetite
Deficiency: neuropathy, Wernicke encephalopathy (eye probs), beriberi disease (nerve inflammation)
Source: meats, dry beans/peas, PB, enriched whole grain bread, milk, eggs
If pt presenting w/ encephalopathy/alcoholis treat w/ thiamine
Vitamin B2- Riboflavin
Coenzymes for proteins/glucose metabolism, fatty acid synthesis, electron transporter
Deficiency: Cheilitis, burning/itchy/sensitive eyes, glossitis/scarlet tongue
Sources: dairy, meat, fish, leafy veggies, enriched/whole grain breads, cereal
Vitamin B3-Niacin
Required by all cells, coenzyme for energy metabolism, needed for RNA/DNA formation, normal digestion, healthy skin/nervous system
Tryptophan is precursor (60mg=1mg niacin)
Deficiency: Pellagra (dermatitis, hyper pigmentation, glossitis), birth defects
Excess: flush/itchy/tingly, liver failure, DM, gout, hypotension, peptic ulcer disease
Sources: meat, fish, leafy veggies, enriched, cereal, supplements
Benefits: release fatty acids, reduce cholesterol, replacement for statins in high dose
Vitamin B5-Pantothenic Acid
Coenzyme A
Synthesizes sterols, fatty acids, heme
Deficiency (rare): neuritis of limbs, burning feet, vomitting
Sources: meat, fish, legumes, whole grain cereal, milk, fruit, veggies, colonic bacteria
Vitamin B6-Pyridoxine
Coenzymes for protein metabolism
Conversion of tryptophan to niacin, formation of heme
Deficiency (rare): cheilosis, anemia, stomatitis, weak gait, irritability/insomnia, nasolabial seborrheic dermatitis
Excess: peripheral neuropathy, photosensitivity, nausea
Sources: meat, whole grain, leafy veggies, potatoes