Nutrition Flashcards

1
Q

Nutrition

A

study of how living organisms obtain and utilize nutrients needed to grow and sustain life

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2
Q

Nutrients

A

◦ Include most biological macromolecules, vitamins, and minerals
◦ Required for synthesis of new molecules
◦ Required for energy for maintenance, growth, and repair
◦ Obtained through food
◦ Water is considered a nutrient
◦ Levels regulated during and following meals

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3
Q

Macronutrients (simple)

A

◦ Must be consumed in large quantities
◦ Carbohydrates, lipids, proteins

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4
Q

Micronutrients

A

◦ Must be consumed in small quantities
◦ Vitamins, minerals

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5
Q

Essential

A

Must be obtained and absorbed via the digestive system / diet

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6
Q

Nonessential

A

Byproducts of body processes

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7
Q

Recommended daily allowances

A

Amount of nutrient that must be obtained each day
standards set by federal agencies

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8
Q

Calories

A

how macromolecules are measured
◦ 1 calorie = the amount of energy required to raise the
temperature of 1 gram of water by 1 degree Celsius
◦ Body weight is maintained when calories consumed = calories expended
◦ RDA: 225-325 grams / day

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9
Q

Carbohydrates are the most…

A

common macronutrients

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10
Q

Structural classifications of carbs

A

Monosaccharides, disaccharides, polysaccharides

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11
Q

Dietary classification of carbs

A

Sugars, starches, and fibers

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12
Q

monosaccharides

A

glucose, fructose, and galactose

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13
Q

Disaccharides

A

sucrose, lactose, and maltose

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14
Q

Other sugars

A

dextrose, brown sugar, honey, molasses, etc.

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15
Q

Starch

A

Polysaccharide polymer of glucose molecules
◦ Refined starches can be added as thickeners

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16
Q

Fiber

A

Includes fibrous molecules of both plants and animals
◦ Can not be chemically absorbed by the GI tract

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17
Q

Sugars and starch become..

A

glucose

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18
Q

glucose

A

◦ Primary energy supplying nutrient
◦ Makes ATP in aerobic cellular respiration
◦ 4kcal of energy / gram of glucose
◦ Non-essential because it can be synthesized from other monosaccharides by gluconeogenesis
◦ Fibers add bulk
◦ Stimulates peristalsis & lowers cholesterol

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19
Q

Lipids include

A

triglycerides, phospholipids, steroids, and eicosanoids

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20
Q

Which lipid is most common

A

triglycerides

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21
Q

Triglycerides

A

◦ Composed of glycerol and fatty acids, 9kcal energy / gram of fat
◦ 3 categories of fatty acids:
◦ Saturated fats
◦ Unsaturated fats
◦ Polyunsaturated fats
RDA 20g/day

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22
Q

Saturated fats

A

no double bonds, solid at room temperature

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23
Q

Unsaturated fats

A

one double bond, liquid at room temperature

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24
Q

Polyunsaturated fats

A

two or more double bonds, liquid at room temperature

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25
Phospholipids
majority of plasma membrane ◦ Modified triglycerides
26
Cholesterol
is a precursor for steroid hormones, bile salts, vitamin D ◦ Required in the plasma membrane giving it flexibility ◦ Made in body and acquired in diet
27
Proteins
Most structurally and functionally diverse ◦ Needed in adequate quantities to replace worn out protein structures ◦ Amount needed depends on age, sex, or overall health ◦ RDA: 45-60 grams / day
28
Proteins (amino acids)
◦ 8 amino acids are essential meaning they must come from diet ◦ 12 amino acids are synthesized by the body ◦ AAs are not stored so they must be replenished regularly ◦ 4kcal energy / gram of protein
29
Complete proteins
include all essential AAs (animal products)
30
Incomplete proteins
– do not contain all essential AAs (plant proteins)
31
Proteins are a source of
nitrogen (building block for DNA / RNA) – important! ◦ Nitrogen is excreted in urine if in excess ◦ Can be fatal if not high enough
32
Vitamins
Organic molecules required for metabolism ◦ Present in small amounts in food ◦ Water soluble or fat soluble ◦ Essential (must be absorbed from diet) or nonessential (produced as a byproduct of a chemical reaction)
33
Water soluble vitamins
include vitamin B and C ◦ Excess is secreted in urine
34
Fat soluble vitamins
include vitamin A, D, E, K ◦ Absorbed from GI tract lacteals within micelles ◦ Excess stored in fat, may be toxic if taken in excess
35
Vitamin A
Used in promoting eye health, precursor of visual pigment retinal
36
Vitamin B
Helps keep nerve, muscle and blood cells healthy ◦ Required for the formation of DNA ◦ Coenzymes in chemical reactions ◦ Different types include biotin (B7), folate (B9), thiamine (B1) and more
37
Vitamin C
Collagen formation, absorption of iron, growth / development / repair of body cells, serves as an antioxidant (along with A and K)
38
Vitamin D
Forms calcitriol, increases calcium absorption from GI tract
39
Vitamin E
Stabilizes and prevents damage to cell membranes
40
Vitamin K
Required for synthesis of blood clotting proteins
41
Minerals
Inorganic ions obtained from diet, some stored ◦ Required in daily amounts, all are essential and must be obtained from diet ◦ Can be major (>100mg/day required) or minor (<100mg/day required) ◦ Fortified – adding essential nutrients
42
Iron
in hemoglobin, binds oxygen; in mitochondria, in electron transport chain
43
Calcium
required for the formation and maintenance of the skeleton, muscle contraction, blood clotting, exocytosis of neurotransmitters
44
Sodium and Potassium
maintaining a resting membrane potential in excitable cells, required to generate action potential
45
Iodine
precursor for thyroid hormone
46
Zinc
involved in protein synthesis and wound healing
47
MyPlate
United States Department of Agriculture’s (USDA) recommendation of desired proportions of food
48
Nutrition food labels
Provide details on composition of prepackaged items
49
Absorptive state
– Time eating, digesting, and absorbing nutrients – Lasts ~4 hours after a meal – Concentrations of glucose, triglycerides, and amino acids increased as absorbed from GI tract
50
Insulin
maintains blood glucose levels (70 – 110 mg/Dl) * hormone released by pancreas when blood sugar is high – Stimulates liver and muscle cells to form glycogen – Stimulates lipogenesis and increases uptake of triglycerides from blood – Stimulates amino acid uptake accelerating protein synthesis
51
Postabsorptive state
– Time between meals, body relying on stored nutrients, ~12 hours
52
Glucagon
maintains blood glucose levels * Regulatory hormone released from pancreas in response to decreased blood glucose levels – Stimulates liver to increase breakdown of glycogen to glucose – Gluconeogenesis from non-carbohydrate sources – Adipose tissue breakdown to triglycerides
53
Cholesterol synthesis
occurs in hepatocytes – Fatty acids transported in blood enter hepatocytes » Synthesis depends on cholesterol intake Following its formation: ◦ Released into blood wrapped by a lipoprotein or ◦ Synthesized into bile salts as part of bile ◦ 90% of these reabsorbed while moving through ileum ◦ 10% lost in feces
54
Chylomicrons
deliver lipids from GI  liver, adipose, muscle (energy) – Formed in intestine from diet into lacteal
55
Lipoproteins
– Are associated with the transport of lipids from the liver  peripheral tissues * Lipids with a protein “wrap” for transport – Three types
56
Very-low-density lipoproteins (VLDLs)
Contain the most lipid lipid delivery vehicles  cells ◦ Various types of lipids + protein ◦ Assembled in liver and released into blood ◦ Transports triglycerides to peripheral tissue – especially adipose ◦ Releases triglyceride  becomes LDL
57
Low-density lipoproteins (LDLs)
Less lipid cholesterol delivery vehicles  cells ◦ High amounts of cholesterol ◦ Bind to LDL receptors in plasma membrane of cell ◦ Engulfed by endocytosis ◦ Cholesterol incorporated into plasma membrane or used as a building block to produce steroid hormones
58
High-density lipoproteins (HDLs)
Least amount of lipid transport lipid from peripheral tissue > liver – Proteins formed in liver and released into blood – Circulate through blood and “fill” with lipids – Can make cholesterol available to steroid-producing tissue – Returned to liver and extra cholesterol is converted  bile salts
59
additional functions of liver
Carb metabolism protein metabloism lipid metabolism lipid transport
60
Carb metabolism
-Monossacharides absorbed from small intestine into blood and then enter the hepatocytes. Fructose and galactose are converted to glucose -Non-carbs converted to glucose via gluconeogenisis -Glucose > glycogen by glycogenisis and reverse by glycogenylysis
61
Protein metabolism
Deamination: amine group removed from amino acids. NH2 is converted to urea and urea enters the blood (eliminated by kidneys) Remaining elements oxydized in cell. resp. to generate ATP Amino acids used to form proteins and plasma proteins Transamination: amino acids converted from one form to another
62
Lipid metabolism
Fatty acids joined with glycerol to form triglycerides (lipogenesis) Fatty acids removed from tryglyceride = lipolysis Fatty acid brake down into acetyl CoA (beta-oxidization) Acetyl CoA change to ketone bodies (water soluble molecules); ketone bodies released into blood, transported to other cells to be oxidized in cell resp. Acetyl CoA used in cholesterol synthesis: released into blood within VLDL's and some used to make bile salts and released as a component of bile.
63
Lipid transport
Transport trygliceride and cholesterol (within VLDL's and LDL's) from liver to peripheral tissue empty HDL released to pick up lipids from tissues and blood and return as full HDL
64
stages of Aerobic cellular respiration
Glycolysis Intermediate stage Citric acid cycle Electron transport system
65
Glycolysis (stage 1 of cell resp)
* Anaerobic pathway in cytosol * 1 glucose > 2 pyruvate * 2 ATP formed
66
Intermediate stage (stage 2 of cell resp)
* Aerobic pathway in mitochondria * Pyruvate > Acetyl CoA * CO2 formed
67
Citric acid cycle (stage 3 of cell resp)
Acetyl CoA > Citric acid
68
Electron transport system
* Transferring of H+ and electrons from NADH and FADH2 * ATP formation through oxidative phosphorylation
69
Interconversion
changing macromolecule form
70
Metabolic rate
◦ Measure of energy used in a given period of time
71
Basal metabolic rate (BMR)
◦ Amount of energy used a rest ◦ Measured with a calorimeter or a respirometer ◦ Varies due to age, lean body mass, sex, and hormone levels ◦ Decreases with age ◦ Thyroid hormone increases BMR ◦ Body surface area is important ◦ Greater surface of skin = greater heat lost ◦ Heat loss = cell energy required to make up for this
72
Total metabolic rate (TMR)
◦ BMR + physical activity ◦ Also influenced by environmental factors
73
Temperature homeostasis
◦ Variable heat produced due to variable metabolic rate ◦ Body temperatures maintained within certain physiological limits: 98.6⁰F neural and hormonal
74
Neural control
mediated through hypothalamus ◦ Ex. Sweating / shivering / vasodilation ◦ Can initiate change in cortex (conscious) ◦ Ex. Behaviorally: put a coat on
75
Hormonal control
mediated by thyroid hormone, epinephrine, growth hormone, and testosterone ◦ Thyroid hormone is the most significant ◦ Release signaled by hypothalamus increases the metabolic rate of cells
76
Core body temperature
◦ Temperature to vital portions of they body kept relatively constant ◦ Maintained by fluctuating blood flow to peripheral regions