NUR 118 - Week 11 - Chemical Regulation/ABG Flashcards
List 3 ways the body maintains its acid base balance
1) Buffers – first line of defense - Blood & Tissue fluid
Carbonic acid-sodium bicarbonate buffer 90% of metabolic processes in ECF
Phosphate - regulate in ICF
Protein system buffers intracellular fluid and plasma
2) Respiratory control of carbon dioxide PaCO2 (LUNGS = CO2)
3) Renal control of bicarbonate HCO3 (KIDNEY EXCRETES OR HOLDS BICARB)
Interpretation of arterial blood gases (ABG’s)
-Know normal values of pH, PaCO2, HCO3
MUST KNOW
pH = 7.35 – 7.45
PaCO2 = 35 – 45
- CO2 = acidic
- >45 = acidic
- <35 = alkaline
HCO3 = 22 – 26
- HCO3 = Alkaline
- >26 = Alkaline
- <22 = Acidosis
Analyze ABG’s for the following 4 conditions:
-respiratory acidosis
-respiratory alkalosis
-metabolic acidosis
-metabolic alkalosis
Think: Alkalosis = Low CO2 = Hyperventilation (anxiety d/t exam)
What is the relationship between respiratory and Acid-Base Balance
Hyperventilation:
CO2 (acidic) is blown off = Respiratory Alkalosis
Hypoventilation:
CO2 (Acidic) is NOT being blown off = Respiratory Acidosis
What are respiratory issues that can effect Acid-Base Balance
Respiratory Acidosis:
HYPOVENTILATION
IMPAIRED GAS EXCHANGE
COPD
Drug overdose
Alcohol intoxication
Respiratory arrest/APNEA
Airway obstruction
Respiratory Alkalosis
-HYPERVENTILATION d/t:
Panic
Anxiety
Sepsis/Fever
Pain
DKA
Hypokalemia (release of potassium)
Patients with renal/kidney disease are in acidosis or alkalosis?
How?
Pts hold onto electrolytes and fluid which leads to metabolic acidosis
Patients who are vomiting are in acidosis or alkalosis?
How?
Leads to metabolic alkalosis
- Patient is vomiting acid
Patients with diarrhea are in acidosis or alkalosis?
How?
Metabolic acidosis
- HCO3 is released in stool
Metabolic Acidosis:
Causes
s/s
Treatment
Cause:
Renal Failure
Diarrhea = loss of HCO3
Uncontrolled diabetes
s/s:
Kussmaul Breathing
Headache
Confusion
Weakness
Treatment:
Bicarbonate
Treat cause
Metabolic Alkalosis:
Causes
s/s
Treatment:
Cause:
Renal failure
GI issues r/t loss of gastric secretion
- Vomiting
- Gastric Suction
- Diuretics
s/s:
Hypertonic Muscles
Hypoventilation
Dizziness
Treatment:
Antiemetics
K+ Replacement
Furosemide r/t Acid-Base Balance
Side effects
Hypokalemia (Low Potassium)
- Metabolic Alkalosis