nucleotide biosynthesis. Flashcards
1
Q
What pathways are nucleotides involved in?
A
Energy metabolism (ATP), Enzyme cofactors (NAD+), and signal transduction (cAMP).
2
Q
Nucleic acid functions
A
Storage of genetic info, transmission of genetic info (mRNA), processing of genetic info (ribozymes), protein synthesis (tRNA, rRNA)
3
Q
Purine biosynthesis is regulated by what molecules?
A
AMP, ADP, IMP, GMP.
4
Q
Final step in pyrimidine biosynthesis?
A
CMP
5
Q
5-fluorouracil is an inhibitor of what?
A
thymidine synthesis
6
Q
Another name for anti-metabolite?
A
Inhibitor
7
Q
Ribonucleotide Reductase activates the tyrosine radical with?
A
Iron co-factor
