Blood Flashcards

1
Q

Blood Volume

A

4-6 liters

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2
Q

Blood temperature

A

38C (100.4F)

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3
Q

pH of blood

A

7.35-7.45

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4
Q

Composition of Blood

A

55% plasma, 44% erythrocytes,

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5
Q

Hematocrit

A

Percentage of blood volume made of RBC. Males-40-54%, Females-37-47%

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6
Q

Plasma Composition

A

92% water by weight, 7% protein by weight

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7
Q

Buffy coat

A

platelets and leukocytes

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8
Q

Plasma protein

A

60% albumins, 35% globulins, 4%fibrinogen, 1% regulatory proteins.

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9
Q

rouleaux

A

RBC stack to smooth flow

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10
Q

Hemoglobin structure

A

four globular proteins each with one molecule of heme-each heme has one iron ion.

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11
Q

Hemoglobinuria

A

Hemoglobin breakdown products in urine due to excess hemolysis in bloodstream

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12
Q

hematuria

A

Whole RBC in urine due to kidney or tissue damage.

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13
Q

Erythropoietin (EPO)

A

Secreted when oxygen is low. Due to disease or high altitude. produced by kidneys.

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14
Q

RBC development

A

Hemocytoblast-myeloid stem-progenitor-proerythroblast-erythroblast-eject nucleus-reticulocyte-enter blood-erythrocyte.

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15
Q

polycythemia

A

Too many RBC circulating. Increased pressure and viscosity.

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16
Q

Diapedesis

A

WBC leave blood and enter tissues

17
Q

chemotaxis

A

WBC attracted to infection by damaged cells, dead cells, or invading pathogens.

18
Q

Granulocytes

A

Neutrophils, basophils, eosinophil

19
Q

agranulocytes

A

lymphocytes, monocytes.

20
Q

Lymphatic cells

A

B-cells, T-cells, natural killer cells.

21
Q

myeloid stem cells

A

produce all WBC except lymphocytes.

22
Q

Normal WBC count

A

5,000-10,000 cells per microliter.

23
Q

Platelet count

A

150,000 to 500,000 per microliter.

24
Q

Phases of hemostasis

A

Vascular, platelet, coagulation…….clot retraction.

25
Q

margination

A

WBC is slowing down in blood vessel

26
Q

neutrophils

A

Most abundant WBC. Phagocytic cell with multi-lobed nucleus. First to respond and pus is dead neutrophils. Granulocytes

27
Q

Eosinophils

A

Granulocyte with granules stain bright red. More present in AM (diurnal) with divided, lobed nucleus. Worm and allergic reaction.

28
Q

Basophils

A

Granules dye blue. Effector cells in allergic reaction that dilate the capillary walls.

29
Q

Monocytes

A

Agranulocytes. Become macrophages once chemotaxis in tissue.

30
Q

Natural killer cells

A

Largest lymphocytes. Kills virus infected and tumor cells without prior stimulation. Innate response

31
Q

Thrombocytes

A

Platelets from megakaryocytes.

32
Q

Erythropoiesis

A

Red cell production