Blood Flashcards

1
Q

Blood Volume

A

4-6 liters

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2
Q

Blood temperature

A

38C (100.4F)

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3
Q

pH of blood

A

7.35-7.45

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4
Q

Composition of Blood

A

55% plasma, 44% erythrocytes,

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5
Q

Hematocrit

A

Percentage of blood volume made of RBC. Males-40-54%, Females-37-47%

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6
Q

Plasma Composition

A

92% water by weight, 7% protein by weight

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7
Q

Buffy coat

A

platelets and leukocytes

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8
Q

Plasma protein

A

60% albumins, 35% globulins, 4%fibrinogen, 1% regulatory proteins.

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9
Q

rouleaux

A

RBC stack to smooth flow

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10
Q

Hemoglobin structure

A

four globular proteins each with one molecule of heme-each heme has one iron ion.

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11
Q

Hemoglobinuria

A

Hemoglobin breakdown products in urine due to excess hemolysis in bloodstream

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12
Q

hematuria

A

Whole RBC in urine due to kidney or tissue damage.

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13
Q

Erythropoietin (EPO)

A

Secreted when oxygen is low. Due to disease or high altitude. produced by kidneys.

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14
Q

RBC development

A

Hemocytoblast-myeloid stem-progenitor-proerythroblast-erythroblast-eject nucleus-reticulocyte-enter blood-erythrocyte.

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15
Q

polycythemia

A

Too many RBC circulating. Increased pressure and viscosity.

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16
Q

Diapedesis

A

WBC leave blood and enter tissues

17
Q

chemotaxis

A

WBC attracted to infection by damaged cells, dead cells, or invading pathogens.

18
Q

Granulocytes

A

Neutrophils, basophils, eosinophil

19
Q

agranulocytes

A

lymphocytes, monocytes.

20
Q

Lymphatic cells

A

B-cells, T-cells, natural killer cells.

21
Q

myeloid stem cells

A

produce all WBC except lymphocytes.

22
Q

Normal WBC count

A

5,000-10,000 cells per microliter.

23
Q

Platelet count

A

150,000 to 500,000 per microliter.

24
Q

Phases of hemostasis

A

Vascular, platelet, coagulation…….clot retraction.

25
margination
WBC is slowing down in blood vessel
26
neutrophils
Most abundant WBC. Phagocytic cell with multi-lobed nucleus. First to respond and pus is dead neutrophils. Granulocytes
27
Eosinophils
Granulocyte with granules stain bright red. More present in AM (diurnal) with divided, lobed nucleus. Worm and allergic reaction.
28
Basophils
Granules dye blue. Effector cells in allergic reaction that dilate the capillary walls.
29
Monocytes
Agranulocytes. Become macrophages once chemotaxis in tissue.
30
Natural killer cells
Largest lymphocytes. Kills virus infected and tumor cells without prior stimulation. Innate response
31
Thrombocytes
Platelets from megakaryocytes.
32
Erythropoiesis
Red cell production