Nucleotide And Nucleic Acid Metabolism

Question 1

What is made from the parent pyrimidine nucleotide

Answer 1

OMP (orotidine mono phosphate )and C,T,U are made from this

Question 2

What enzyme is used to convert hypoxanthine and xanthine

Answer 2

Xanthine oxidase

Question 3

What inhibits xanthine oxidase in purine degradation

Answer 3

Alopurinol

Question 4

High Uric acid in blood vessels leads to precipitation of Uric acid in the urinary tract and joints and and result in the development of what

Answer 4

Gout

Question 5

What is the condition when there’s stones in urine and tophi

Answer 5

Urolithiasis

Question 6

Adenine and guanine are

Answer 6

Purines

Question 7

Cytosine
Thymine
Uracil

Answer 7

Pyrimidines

t is methylated

Question 8

Polymers of nucleotides are attached by phosphate group

Answer 8

RNA and DNA

Question 9

Which pathway is the formation of inosine 5 mono phosphate

And formation of amp and gmp

Answer 9

Purine anabolic pathway

Question 10

What enzyme is used to convert ribose-5-phosphate to 5-phosphoribosyl-1-pyrophosphate (PRPP)

Answer 10

PRPP synthetase

Question 11

Thymine production specifically for pregnant animals

Answer 11

Folate

Question 12

Rate limiting Enzyme for pyrimidines

Answer 12

Cps2