General phys Flashcards

1
Q

Peptide hormones and growth factors act on target cells by binding to ____ receptors

A

Cell surface

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2
Q

Cholera toxins inhibits the ability of the alpha subunit of G’s to split GTP. The resulting effect is the ___ of Adenyl cycled

A

Stimulation

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3
Q

Most growth factors are :

A

Protein-tyrosine kinase

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4
Q

The first step in growth factor pathway activation is :

A

Receptor dimerization

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5
Q

Cyclic AMP is synthesized from ATP by the reaction of

A

Adenyl cyclase

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6
Q

The ip3 produced by phospholipase C acts to ?

A

Open calcium channels in the ER

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7
Q

DaG or Diacylglycerol and calcium activate

A

Protein kinase c

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8
Q

Protein kinase b regulates glycogen metabolism by ____ of glycogen synthase and thereby relieves its inhibition on glycogen synthase

A

Phosphorylation

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9
Q

If the number of ipsp’s is more than the number of esps’s on a neuron then:

A

Chances for an action potential triggered by the neuron decrease

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10
Q

Osmotic pressure of a solution decreases as the ___ content increases

A

H20

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11
Q

The phospholipid bilayer, a major component of plasma membranes is most permeable to which ion

A

Calcium

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12
Q

A protein that does not span through the entire phospholipid bilayer is

A

Peripheral membrane protein

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13
Q

The transport of water across cells in the mammalian body is primarily dependent on the:

A

Number of osmotically active solute particles

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14
Q

what happens if you add hypertonic saline solution to elf

A

icf volume will decrease

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15
Q

Insulin released from the pancreatic cell is released into the circulation and signals on a target cell by binding to the receptor and the cellular response is increased glucose uptake. The receptor Is:

A

Cell surface, receptor tyrosine kinases

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16
Q

Serum proteins in capillaries contribute to High:

A

Oncontic pressure in the capillaries

17
Q

A physiological phenomenon that describes a responsive adjustment to an environmental stress that is irreversible and is passed through genes to the next generation

A

Adaptation

18
Q

Increasing extra cellular K will cause the resting membrane potential to:

A

Increase

Make inside of cells more positive

19
Q

Beta adrenergic receptor of a hepatocyte regulate glycogen metabolism. This receptor is an example of:

A

GPCR

19
Q

In gcpr , what activates protein kinase a

A

Cyclic amp

20
Q

Steroid hormones are usually

A

Transcription factors

Targets of ligand receptor complexes

22
Q

insulin is secreted from the pancreas and affects glucose uptake in skeletal muscle. this is an example of ___ signaling.

A

endocrine

23
Q

sodium potassium pump is present on the ___ of intestinal cells

A

basolateral membrane

24
Q

a mutation of the na-k pump in a pig resulted in loss of its function; this will abolish the na gradient across the cell membrane. the glucose transport process that is affected by this defect is

A

co transport

25
Q

dehydration will lead to loss of water from

A

ecf and icf

26
Q

describe plasma membrane

A

phospholipid bilayer surrounding the cell

27
Q

what are the components of the extracellular fluid

A

plasma, interstitial fluid, trancellular membrane

28
Q

vitamin d acts by binding to __ receptor

A

intracellular

29
Q

epinephrine or glucagon bind to their __ receptors on the membrane and activate the cAMP

A

GPCR