NTIs

Question 1

Aminoglycocides

Answer 1

Bacterial infections
Gentamycin 5-10mcg/mL
Tobramicin 20-40mcg/mL
Gentamicin level

Question 2

Lithium

Answer 2

Bipolar disorder
0.6 meq/L
Lithium level

Question 3

Levothyroxin

Answer 3

Hypothyroidism
0.4- 4.0 mlu/L
Thyroid function
TSH level

Question 4

Warfarin

Answer 4

Thrombosis
2-3 INR
INR

Question 5

Phenytoin

Answer 5

Seizure
10-20 mL/L
Phenytoin level

Question 6

Clozapine

Answer 6

Schizophrenia
350-600mg/mL
WBC count
Absolute neutrophil count

Question 7

Digoxin

Answer 7

Atrial fibrillation
4-10mg/L
Digoxin level
Check for hypokalemia
Increase toxicity

Question 8

Heparin

Answer 8

Thrombosis
46-70ppt
INR

Question 9

Methotrexate

Answer 9

Rheumatoid arthritis
Under 1 micromol/L at 48h
FBC, LFT’s, U&E’s

Question 10

Theophylline

Answer 10

Asthma, COPD
10-20mg/mL
Theophylline level

Question 11

Valproate

Answer 11

Seizures
50-100mcg/mL
Serum valproic acid level
CBC, hepatic function test

Question 12

Procainamide

Answer 12

Heart arrhythmia
4-10mcg/mL
ECG monitoring
QRS complex, QT interval, BP

Question 13

Cyclosporine

Answer 13

Immunosuppressant
The therapeutic range depends on the clinical situation
Blood cyclosporine concentration
LFT, FBC, U&Es

Question 14

Quinidine

Answer 14

Heart arrhythmia
1-4 mcg/mL
Serum quinidine level, BP, QRS duration
QT interval

Question 15

Carbamazepine

Answer 15

Seizures
4-10mg/mL
Serum level

Question 16

Phenobarbital

Answer 16

Seizures
10-40mg/L
Serum phenobarbital concentration

Question 17

Tacrolimus

Answer 17

Immunosuppressant
5-10mcg/L
Renal function
Hepatic
Electrolytes (Mg, Phos, K)

Question 18

Vancomycin

Answer 18

Bacterial infections
20-40mcg/mL
Vancomycin level