Normal microbiota of GI tract

Question 1

Enterococcus

Answer 1

GI tract
General
-*Gr+ cocci, pairs or short chains 
-*Facultative anaerobes
-*Catalase -
-γ-hemolytic 
-Bile-esculin +
-PYR+
-Opportunists
-HAIs 
   -UTIs, wound infect., endocarditis, **intraabdominal abscesses, bacteremia 
Virulence
-*Intrinsic and acquired antibiotic resistance
-Adhesins
   -*pili
-*biofilms

Question 2

Bacteroides

Answer 2

GI tract
General
-Gr- pleomorphic rod
-Normal microbiota mouth, colon, GU humans, animals
-causes *Peritonitis, intraabdominal abscess
-Aerotolerant anaerobe
-bile-tolerant
-*Dominant genus in colon
-*Bacteroides fragilis 
Virulence
-LPS
-Capsule (*capsule alone stimulates abscess formation)

Question 3

Peritonitis, abscesses

Answer 3

GI tract
-Normal GI microbiota are etiologic agents of acute peritonitis and abscesses associated w/ bowel rupture
-Only 4-6 species generally recovered from intraabdominal infections
-E. coli and other enteric Gr- rods
-Enterococci
-Viridans streptococci
-Clostridia
-Bacteroides fragilis
Pathogenesis
-peritonitis,bacteremia–>intraabdominal abscesses
Symptoms
−Abdominal pain
−Abdominal distention
−*Fever