Non Obstructed LUTD Flashcards

1
Q

What are the 3 components of the lower urinary tract?

A
  1. bladder
  2. urethra
  3. prostate
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2
Q

What are the 6 things we will with LUTD?

A
  1. Dysuria
  2. Pollakiuria/ periuria
  3. Stranguria
  4. Pigmenturia
  5. Incomplete voiding: palpate bladder after urinating and still has urine in it
  6. Urinary incontinence
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3
Q

Define dysuria

A

painful peeing

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4
Q

Define pollakuria/periuria

A

peeing all over the place; excessive urination

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5
Q

Define stranguria

A

straining to pee

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6
Q

Define pigmenturia

A

different color of pee than what it normally is

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7
Q

What causes dysuria/stranguria/pollakiuria?

A
  1. Irritation of bladder: bacterial, uroliths, interstitial cystitis
  2. Neurological bladder
  3. Secondary LUTD
  4. Neoplasia
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8
Q

How do we dx LUTD?

A
Use fricken everything. 
Collect urine free flow and cystocentesis 
Urinalysis including microscope exam/sedimentation
Urine culture
Urine cytology 
Rads
US
Contrast studies etc etc etc
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9
Q

One of the main things we see with LUTD is discolored urine. What color will bilirubinuria be? What about hematuria?

A
Bilirubin = dark yellow/orange
Hematuria = red/port wine
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10
Q

T/F Bacterial agents tend to be the major cause behind UTIs.

A

True. Bacteria account for 99% of infections

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11
Q

What is the incidence of UTIs in dogs and cats?

A

Dogs: common: 14% of dogs affected: female
Cats: less common; incidence increases with advancing age

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12
Q

What 4 things cause LUTD?

A
  1. UTI
  2. pyuria (pus inside urine >5 WBC/HPF high powered field)
  3. Significant bacteriuria
  4. Inflammation (cat) vs infection (dog)
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13
Q

T/F Microbial factors include adherence factors, hemolysin, urease, mucosal defenses and capsules.

A

False, includes all of those except mucosal defenses.
Mucosal defenses, normal micturition, urine properties, immune system and anatomy are all ways in which the host protects itself.

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14
Q

What is the most common microbial isolate?

A

E. coli most common (33-50%)

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15
Q

What is the second most common microbial isolate?

A

Gram positive cocci (25-33%)

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16
Q

T/F Most infections contain multiple species.

A

False. Most infections are single species: 75%

17
Q

Ascending or hematogenous is the most common route of infection?

A

Ascending

18
Q

What is our gold standard test?

A

Urine culture!!!

19
Q

How do we tx uncomplicated UTIs?

A

Drug choice: Amoxicillin and cephalosporins, TMS

Duration: 10-14 days

20
Q

Are cultures necessary for complicated UTIs?

A

Yes!!

21
Q

What is the difference btwn reinfection/superinfection and relapse?

A

Reinfection/superinfection is infection with new or different organism

Relapse is infection with the SAME organism/strain

22
Q

Explain reinfection/superinfection UTIs

A
  • New/different organisms
  • C & S positive >7 days after last tx course (REINFECTION)
  • C & S positive at day 7 after starting antibiotics (SUPER)
23
Q

Explain relapse UTIs

A
  • SAME organism/strain 7 days AFTER last tx
  • have to look into inappropriate drug, dose, frequency, duration
  • pyelonephritis, nidus of infection
24
Q

How do we determine the cause of a RECURRENT UTI?

A
  1. Imaging: Rads and US
  2. CULTURE NECESSARY!
  3. Search for underlying dz
  4. Search for a nidus (stone, suture)
25
Q

During tx of RECURRENT UTI, when do we culture?

Pre therapy
During therapy
Post therapy

A

CULTURE AT ALL 3 TIMES!

26
Q

How long do we tx RECURRENT UTI?

2-4 wks
4-6 wks
6-8 wks
8-10 wks

A

Extended course (4-6 wks)

27
Q

How do we tx a REINFECTION UTI?

A

Prophylactic Therapy!

  • once infection is eradicated
  • LAST RESORT
  • drug that concentrates in urine; few side effects
  • once daily, bedtime administration so it sits in der alllll night, 30-50% of original dose
  • Nitrofurantoin is good choice! Urinary disinfectant
  • regular microbiology (q 4 weekly)
  • if negative C & S for 6 months - discontinue!
  • monitor C & S for 3 months after discontinuation (q 1 monthly) then q 3 months (1 yr)
28
Q

What species is primarily responsible for fungal UTIs?

A

Candida spp