Gastric Diseases Flashcards
The mucosa is part of the gastric layer. Name the 5 parts that make up the mucosa.
- Superficial epithelium
- Lamina propria: below epithelium; loose CT, immune cells, nutritional support
- Gastric glands: mucous neck cells, parietal cells (H/K ATPase pump-HCL), chief cells (digestion)
- Neuroendocrine cells: Serotonin, Histamine, Somatostatin, Gastrin
- Muscularis mucosa- thin muscle layer
The following describes which gastric layer?
Dense CT, structural support; blood vessels & lymphatics; Meissner’s plexus- nervous system
Submucosa
The following describes which gastric layer?
Layers of smooth muscle perpendicular to each other; Auerbach’s (Myenteric) plexus
Muscularis
The follow describes which gastric layer?
CT layer
Serosa
T/F Pepsin breaks down protein and gastric lipase breaks deals with fat digestion.
Yep. True.
T/F The pancreas is the ONLY organ in the cat that makes intrinsic factor.
True
T/F The pancreas is the ONLY organ in the dog that makes intrinsic factor.
False- stomach and pancreas both make it.
What can be found on the CBC of an animal with primary gastric dz?
NSF
Regenerative anemia from bleeding
Leukocytosis
T/F We can expect to see HYPOchloremia, HYPOnatremia and HYPOkalemia in the chemistry of an animal with primary gastric dz.
True
If azotemia is present in the animal with primary gastric disease, where is the problem located?
Pre-renal
What on the chemistry of an animal with primary gastric disease would suggest bleeding in upper GI tract?
BUN elevation alone or disproportionately higher than creatinine
If metabolic alkalosis with increased bicarbonate and decreased chloride is found on the chemistry of an animal with primary gastric disease then what might this make us think?
we should CONSIDER gastric outflow obstruction
What is the best way to evaluate for inflammation, ulcer, FB or mucosal neoplasia?
Endoscopy!
What are the cons of endoscopy?
Disease deeper than mucosa, fxn’al assessment
The following is associated with what?
Inflammation of mucosa
Sudden onset of clinical signs
Symptomatic and supportive care
‘Biopsy dx’ but we often presume
Acute gastritis
How do we tx Acute Gastritis?
Treat underlying dz if known . . .
Fluids Antacids Anti emetics (once FB ruled out and/or vomiting protracted or severe enough to cause dehydration and electrolyte imbalances) Pain medications Water and bland diet reintroduction
T/F Gastritis can induce significant mucosal changes.
True
T/F If an animal has a FB, they will present with persistent clinical signs.
You’re not wrong but you’re also not right.
A gastric FB can present with persistent OR intermittent clinical signs.
T/F FB’s are only found in dogs.
No, stupid. Dogs and cats.
Dramatic gastric distension in stomach is called what?
Dilation
Stomach twisting and moving on axis to left of fundus is called what?
Volvulus
The following things are the resulting pathology from what condition?
Compressions of CVC --> impaired venous return to heart --> hypovolemic shock Gastric wall necrosis Splenic torsion or avulsion Congestion of abdominal viscera Endotoxic shock DIC
Gastric Dilation and Volvulus (GDV)
Large or small breed dogs are predisposed to GDV?
Large
T/F Barrel chested dogs are predisposed to GDV.
True
T/F a dog that eats fast and then plays is predisposed to GDV.
True! Aerophagia