Non-mendelian Inheritance Flashcards
What is epigenetic inheritance
A pattern in which a modification occurs to a nuclear gene or chromosome that alters gene expression
What causes epigenetic changes?
DNA and chromosomal modifications
Dosage compensation
offset differences in the number of active sex chromosomes
What is a mechanism of dosage compensations?
DNA methylation; results in gene silencing
How does dosage compensation occur in mammals?
The inactivation of a single X chromosomes in females
When does X-Chromosome Inactivation occur?
Early in development
In mammals, what does X-chromosome inactivation depend on?
The X-inactivation center
If one of the two X-Chromosomes is missing its Xic due to a mutation, a cell counts only ___
One Xic and X-chromosome inactivation does not occur
Genomic Imprinting
A segment of DNA is marked and the effect is maintained throughout the life of the organism
Maternal effect
Involves genes in the nucleus; genes encode RNA and proteins in the egg