Non-melanoma skin cancer Flashcards

1
Q

what does uvA do to skin?

A

Ageing

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2
Q

What does UvB do to skin

A

Burns

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3
Q

red flags for skin cancer

A

Open sore that doesn’t heal in 3 weeks
Sore/spot that itches/stings/crusts etc
Any mole that change sin colour, size etc

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4
Q

What are the two types of non-melanoma skin cancer?

A

basal cell cancer

squamous cell cancer

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5
Q

Sx BCC

A
  • Waxy papules with central depression
  • Pearly appearance
  • Firm, pale area that is small, raised or translucent
  • Erosion and ulceration is often central
  • Bleed easily with trauma
  • Crusting
  • Raised border
  • Slow growing and non-healing
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6
Q

Treatments BCC

A
  • Excision biopsy: 3-5mm margin of normal skin
  • Mohn excision: excised tissue examine under microscope layer by layer to ensure all cancer is gone - high clearance rates - used in high risk areas like eyes, lips, nose
  • Superficial skin surgery: shave, curettage and electrocautery
  • Cryotherapy
  • Photodynamic therapy
  • Radiotherapy
  • 5-flurouracil cream
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7
Q

SCC sx

A
  • Enlarging scaly/crusty lumps - arise within pre-existing keratosis or carcinoma
  • Grow weeks-months, may ulcerate and often tender/painful
  • Sun-exposed areas like face, lips, ears, forearms etc
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8
Q

Dx SCC

A
  • Biopsy and staging investigations

- Image using US/CT/MRI/biopsy

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9
Q

Tx SCC

A

Surgery - shave, curettage and electrocautery for low risk

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10
Q

What is actinic keratoses

A
  • Pre-cancerous
  • May be solitary but often multiple
  • Sun-exposed sites (face, ears and hands)
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11
Q

Sx actinic keratoses

A
  • Enlarging scaly/crusty lumps - arise within pre-existing keratosis or carcinoma
  • Grow weeks-months, may ulcerate and often tender/painful
  • Sun-exposed areas like face, lips, ears, forearms etc
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12
Q

tx actinic keratoses

A

Cryotherapy, curettage, excision

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13
Q

how to minimise skin cancer

A
  • Sun cream
  • Stay indoors in middle of day
  • Covering clothing
  • Avoid sunbeds
  • Skin checks
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14
Q

From which cells do squamous and basal cell carcinomas originate

A

Keratinocytes

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