non IV sedation

Question 1

as soon as a child receives a sedative medication outside of nitrous

Answer 1

1) you may NOT deliver a second agent without a permit
- like nitrous

Question 2

adults with multiple medical comorbities

Answer 2

1) drug interactions increase or decrease CYP 450
2) anxiety level pre-op can delay gastric emptying
3) depression benzodiazepines can worsen signs and symptoms

Question 3

pediatric

Answer 3

1) clarks and youngs rule for single dose sedatives
2) physiology is different, metabolism is fast

Question 4

enteral sedation

Answer 4

1) absorption across the enteric membrane of the gastrointestinal tract
2) includes rectal, oral, sublingual

Question 5

parenteral sedations

Answer 5

1) IV
2) intramuscular
3) inhalational
4) intranasal

• none are enterohepatic

Question 6

enterohepatic circulation

Answer 6

1) small portion undergo a cycle of biliary secretion and reenter the small intestine
2) drugs admin via enteral route
- this compounds the biliary circulation

Question 7

pharmakokinetics

Answer 7

1) how drugs move in the body

Question 8

pharmacodymamics

Answer 8

1) how the drugs work

Question 9

drugs half life

Answer 9

1) steady state: therapeutic level is maintained after 4 half lives creating a constant level of sedation
2) rate of accumulation = rate of elimination

Question 10

premedication versus sedation

Answer 10

1) latent period - time between admin of drug and onset

Question 11

oral sedation

Answer 11

1) most common, economical, and convenient

Question 12

oral conscious sedation

Answer 12

1) minimally depressed level of consciousness
2) pt can maintain airway and respond to physical stimulation or verbal command

Question 13

single dose sedation anxiolytics

Answer 13

1) diazepam
2) lorazepam
3) triazolam
4) midazolam