nitrous Flashcards
inhalation
1) sedation with N2O and O2 is very safe
2) >20% oxygen using a failsafe
3) titrate to effect
4) analgesic properties
inhalation advantages
1) more rapid (2-3 mins)
2) peak clinical effect
3) sedation level readily changed in either direction
4) duration is variable and controllable
5) recovery 3-5 minutes with 100% O2
contraindications
1) congestive heart failure (for sure)
2) relative
- COPD
- pregnancy 1st trimester avoid
- claustrophobia
disadvantages
1) initial cost of equipment
2) cost of gases
3) N2O not a potent agent
3) chronic exposure can be detrimental
N2O chemical properties
1) relative insoluble in blood
2) low potency
3) 100x more soluble than oxygen
4) fills air spaces 35x faster than N2
- caution with pneumothorax, bowel obstruction, and typanoplasty patients
concentration effect
1) more gas delivered leads to more gas absorbed
diffusion hypoxia
1) rapid diffsion of H2O from blood to alveoli
2) this is why we give oxygen after the procedure
chronic exposure pitfall
1) unknown what N2O does to system