Non-HIV Viruses Flashcards
True or false: Mild to moderate chickenpox requires no treatment
True
Acyclovir should be started how soon within presentation of rash?
24 hours
Which antiviral options may be used for chickenpox in children 2-12yrs?
. Valacyclovir
. Acyclovir
True or false: Antiviral treatment for shingles should last for longer than 72 hours
False. Benefit of antiviral therapy greater than 72 hours is not clear
Adjunctive treatment options for postherpetic neuralgia (PHN)
. Gabapentin
. Lidocaine patch
. Opioids
. Nortriptyline or amitriptyline
What agent should be initiated if rash develops after high titer varicella zoster immune globulin?
Acyclovir within 24 hours of rash
What agent should be initiated for presentation of oral herpes lesions?
Valacyclovir 2gm PO Q 12 H for 1 day
True or false: Topical regimens are preferred for treatment of oral herpes lesions
False. Systemic agents preferred
Duration of genital herpes treatment recommended for immunocompetent vs immunocompromised patients?
Immunocompetent: 5 days
Immunocompromised: 5-10 days
What agent may be used in acyclovir-resistant HSV?
Foscarnet 90mg/kg IV q 12 h x 7 days
Influenza is (single/double) stranded (DNA/RNA)
Single. RNA
Which types of influenza are seen in human infections?
Types A and B
Difference between antigenic drift and antigenic shift?
Drift- point mutations. small changes in hemagglutinin and/or neuraminidase molecules
Shift - acquires new hemagglutinin or neuraminidase
Which antiviral therapy should be initiated for rabies treatment?
No proven antiviral therapy
How many rabies vaccines do immunocompetent vs immunocompromised patients receive?
Immunocompetent: 4 doses
Immunocompromised: 5 doses
