Non-HIV Antiviral Flashcards
How are flus named?
surface antigens H (hemagglutinin) and N (neuraminidase), eg H1N1 and H3N2
Strategies for flu management
prevention, antiviral, symptoms
three types of flu vaccines
inactivated, recombinant, attenuated
SE of flu vaccine
soreness, fever, myalgia, malaise
These are immune system reactions, not the flu itself
Severe, rare side effect of flu vaccine
Guillan-Barre – immune response that leads to weakness and potential paralysis. Usually reversible.
What type of flu vaccine should someone with an egg allergy take?
Any! But to avoid any concerns, recombinant hemagglutinin vaccine (RIV) are an egg-free option
Who should not take the live, attenuated influenza vaccine (nasal spray)?
Kids under 2, immunocompromised, gestating parents AND THEIR FAMILIES
When should flu vaccine be administered
October/November, potential booster in April for >65 or immunocompromised
Is egg allergy a contraindication for the flu vaccine
No, but monitor for 15 minutes
Brand name of Oseltamivir
Tamiflu
t/f: Tamiflu can be used for only prophylaxis
false, prophylaxis and treatment
Drug class of oseltamivir (Tamiflu)
neuroaminidase inhibitor
Timing considerations for Tamiflu
- no more than 2 days after symptoms first appear (ideally within 12 hours)
- prophylaxis up to 10 days
- discontinue 48 hours before live attenuated influenza vaccine
AE for oseltamivir (Tamiflu)
Rare: SJS, neuropsych in young
Which hepatitis doesn’t have a vaccine
Hep C