Non-Depolarizing/Depol. Neuromuscular Blocker

Question 0

Pancuronium

Answer 0

Non-depol NM Blocker
N(m), M(2)
Slow onset (2-4mins), Long action (2-3hrs)
Vagal blockade and tachycardia. Can block presynaptic M2 and inc NE release.

Question 1

d-tubocurarine

Answer 1

Non-depol. NM blocker
N(m) 
- Slow onset (4-6mins)
- long action (2-3hrs) 
may cause histamine release

Question 2

Vecuronium

Answer 2

Non-Depol NM Blocker
no class
N(m)
- onset 2-4mins, action 20-40mins

Question 3

Cistaracurium

Answer 3

Non-depol. NM blocker
N(m)
Onset 2-4mins, action 20-40mins
Broken down into Laudanosine, possible decrease of seizure threshold

Question 4

Atracurium

Answer 4

Non-depol NM blocker
-Onset 2-4mins, Action 20-40mins
Broken down into Laudanosine, decreasing seizure threshold

Question 5

Rocuronium

Answer 5

Non-depol NM blocker
No class
N(m)
-Rapid onset (1-2min), Duration of Action (20-35min)

Question 6

Succinylcholine

Answer 6

DEPOLARIZING NM BLOCKER
N(m)
Onset of action and recovery both occur VERY quickly

Question 7

Mecamylamine

Answer 7

Tertiary Ammonium Compound
Blocks Nicotinic receptors in brain
Cycloplegia, Mydriasis, vasodilation (orthostatic hypotension), tachycardia, Urinary retention, block autonomic reflexes.
Used in HTN emergencies, being tested in Tourette’s.