Muscarinic Antagonist

Question 0

Scopalamine

Answer 0

Muscarinic Antagonist
Alkaloid
M
Sedation and Amnesia (Crosses BBB well), hot skin, tachycardia
— used in presurgical to reduce salivation and bronchiole secretion
Can cause euphoria, some abuse potential
Absorbed through skin, used to treat motion sickness
Used to treat nystagmus

Question 1

Atropine

Answer 1

Muscarinic Antagonist
Alkaloid
M
Does not enter CNS until high does are reached-mainly peripheral.
First step in treated gas/organophosphate/nicotine poisioning

Question 2

Tolterodine

Answer 2

Muscarinic Receptor
M3 blocker
Used to treat over active bladder.

Question 3

Solifenacin

Answer 3

Muscarinic Antagonist
No Class
M3
Used to treat overactive bladder.

Question 4

Oxybutynin

Answer 4

Muscarinic Antagonist
No class
M
combined with trospium to Prevent Bladder spasm after prostate surgery.

Question 5

Glycopyrrolate

Answer 5

Muscarinic Antagonist
no class
M
Dampen vagal response during visceral organ surgery
combat GI side effects from muscarinic agonist use for Mysthenia gravis or nystagmus

Question 6

Dicyclomine

Answer 6

Muscarinic Antagonist
No class
M
GI antispasmodic

Question 7

Ipratropium

Answer 7

Muscarinic Receptor
Quaternary Amine derivative
M
Not absorbed orally, used via inhalation for COPD/Asthma

Question 8

Tropicamide

Answer 8

Muscarinic Antagonist 
No class 
M
Short acting- pupil dilation 
synonymous with HOMOTROPINE

Question 9

Contraindications to the use of muscarinic antagonists

Answer 9

uncontrolled or narrow angle glaucoma

elderly men with BPH

Question 10

diphenoxylate-atropine

Answer 10

opioid + atropine-

used to treat diarrhea and antispasmodic

Question 11

Homatropine

Answer 11

M blocker

Induce Cycloplegia and Mydriasis