NOD-like Receptors (NLR) - Innate Immunity Flashcards
1
Q
NLRs respond to what?
A
cytosolic PAMPs and DAMPs
2
Q
what do inflammasomes activate?
A
caspase-1
3
Q
main function of caspase-1
A
cleave inactive cytoplasmic precursor forms of IL-1 beta and IL-18