NOD-like Receptors (NLR) - Innate Immunity Flashcards

1
Q

NLRs respond to what?

A

cytosolic PAMPs and DAMPs

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2
Q

what do inflammasomes activate?

A

caspase-1

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3
Q

main function of caspase-1

A

cleave inactive cytoplasmic precursor forms of IL-1 beta and IL-18

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