Nicotinic Agonists and Antagonists Flashcards

1
Q

D-Tubocurarine

A

Competative Nicotinic Antagonist

NM Blocker, decreases mepp /epp amplitude, temporal summation, quantal contents, RMP and threshold unchanged

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2
Q

Pancurarine
Atracurarine
Mivacurarine

A

Competative Nicotinic Antagonist Long Duration NMB
Competative Nicotinic Antagonist Medium Duration NMB
Competative Nicotinic Antagonist Intubation

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3
Q

SuccinylCholine

A

Depolarizing Nicotinic Antagonist NM Blocker, increases RMP and Threshold. Induces Na Channel inactivation. Intubation

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4
Q

Hexamethonium
Mecamylamine
Trimethaphan

A

Ganglionic Blocker - Competative Antagonist Competes with Ach for nicotinc receptor in ganglia.
Ganglionic Blocker - Competative Antagonist Competes with Ach for nicotinc receptor in ganglia.
Ganglionic Blocker - Competative Antagonist Controlled hypotension (surgery/hypertensive crisis)

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