Nicotinic Agonists and Antagonists Flashcards
D-Tubocurarine
Competative Nicotinic Antagonist
NM Blocker, decreases mepp /epp amplitude, temporal summation, quantal contents, RMP and threshold unchanged
Pancurarine
Atracurarine
Mivacurarine
Competative Nicotinic Antagonist Long Duration NMB
Competative Nicotinic Antagonist Medium Duration NMB
Competative Nicotinic Antagonist Intubation
SuccinylCholine
Depolarizing Nicotinic Antagonist NM Blocker, increases RMP and Threshold. Induces Na Channel inactivation. Intubation
Hexamethonium
Mecamylamine
Trimethaphan
Ganglionic Blocker - Competative Antagonist Competes with Ach for nicotinc receptor in ganglia.
Ganglionic Blocker - Competative Antagonist Competes with Ach for nicotinc receptor in ganglia.
Ganglionic Blocker - Competative Antagonist Controlled hypotension (surgery/hypertensive crisis)