Adrenergic Antagonists

Question 1

Phenoxybenzamine

Answer 1

Antagonist (Irreversible Alpha-receptor) Causes decreased vasoconstriction, decreased blood pressure. Used to treat Pheo

Question 2

Phentolamine

Answer 2

Antagonist (Reversible Alpha-receptor) Used to diagnose pheo. Pts with pheo will demonstrate larger than expected decrease in BP when given phentolamine

Question 3

Prazosin

Answer 3

Antagonist (Selective Alpha-1) Causes peripheral vascular smooth muscle relaxation, leading to Drop in BP. Decrease prostatic and bladder neck contraction. Used for Hypertension and BPH

Question 4

Terazosin

Tamulosin

Answer 4

Similar to prazosin

Similar to prazosin

Question 5

Propranolol

Answer 5

Antagonist (Beta 1 and Beta 2) B1 block causes decreased HR and Contractility, thus decreased CO. Reflex peripheral vasoconstriction, end eventual decreased BP. Bronchocontstriction. Used for CV disroders (Hypertension, CAD), tachcardia associated with hyperthyroidism, chronic migraines

Question 6

Timolol

Answer 6

Opthalmic solution to decreasedaqueous humore secretion. For wide angle glaucoma.

Question 7

Metoprolol

Answer 7

Antagonist (selective Beta-1) Heart rate and contractility are decreased, leading to decreased CO. Used to treat Hypertension and CAD especially with patients with diabetes. Used to treat wide angle glaucoma

Question 8

Carvedilol

Labetalol

Answer 8

Antagonists (Alpha 1 and Beta) Treat CHF and refractory hypertension
Antagonists (Alpha 1 and Beta) Treat CHF and refractory hypertension