AntiChE & Pesticides

Question 1

Edrophonium

Answer 1

AntiCHe - quart amine Diagnost MG-provdies quick burst of energy

Question 2

Neostigme

Answer 2

AntiCHe - Carbamate Paralytic Ileus, urinary retention, Myasthenia Gravis, Recovery from NM blockade, Antimuscarinic/nicotinic poisoning

Question 3

Pyridostigme

Answer 3

AntiCHe - Carbamate Myasthenia Gravis, Prophylaxic nerve gas treatment.

Question 4

Physostigme

Answer 4

AntiCHe - Carbamate Narrow angle glaucoma with pilocarpine, Antimuscarinic/nicotinic poisoning

Question 5

Galantamine

Answer 5

AntiCHe - Carbamate Alzheimers to increase memory and body function. Prophylaxic nerve gas treatment.

Question 6

Pralidoxime

Answer 6

Oxime - Reversible Competative OP Antagonist Can displace OP from ACHe and later come off. Is used for treatment of Bioweapons with atropine and anticonvulsant

Question 7

Malathion/Diazonin/Carbaryl

Answer 7

Irreversible AntiCHE - OP Used as an insecticide. We have a carboxylesterase therefore can inactive it. In insects it is metabolized to an active oxon form.

Question 8

Sarin,VX,Tabun,Sowma

Answer 8

Irreversible AntiCHE - OP Nerve agents that need to be aerolized. Can lead to convulsions, loss of body function and respiratory paralysis .