Muscarinic Agonists & Antagonists Flashcards
Acetyl Choline
Muscarinic Agonist - Nonselective Used for cataract suturing. Stimulates all muscarinic receptors –> SLUDGE
Carbamylcholine
Muscarinic Agonist - GI, Bladder, Eye Narrow-angle glaucoma, causes miosis and relaxation of ciliary muscles
Bethanechol
Muscarinic Agonist-GI, Bladder, Eye Urinary retention and post surgical ileus
Acetyl B Methylcholine
Muscarinic Agonist - Heart Analog to Acetylcholine, acts on heart = bradycardia, decreased contractility, decreased conduction
Pilocarpine
Muscarinic Agonist Narrow-angle glaucoma, causes miosis. Xerostonia (dry mouth)
Atropine
Muscarinic Antagonist - Nonselective Depression of PSNS , Intubation-decrease secretions , Surgical manipulation - prevent vagal reflex, Muscarinic mushroom toxicity
Scopolamine
Muscarinic Antagonist - Nonselective Motion Sickness, tranquilize, amnesia
Pirenzopine
Muscarinic Antagonist - M1 Ophthalminc, Peptic Ulcers, Intestinal hypermobility
Tropicomide
Cyclopenolate
Muscarinic Antagonist Mydriasis- retinal/optic disc exam
Muscarinic Antagonist Mydriasis-retinal optic disc exam
Glycopyrolate
Muscarinic Antagonist - Nonselective Intubation - secretions, Counteract -stigme during anesthesia recovery, Surgical manipulation- prevent vagal reflex. Intestinal hypermotility
Tiotropium
Ipratropium
Muscarinic Antagonist- M3 Bronchodilation - COPD, asthma, chronic bronchitus, emphysema
Muscarinic Antagonist- M3 Bronchodilation - COPD, asthma, chronic bronchitus, emphysema, cold
Tolterodine
Darfenacine
Muscarinic Antagonist- M3 Urinary incontinance
Muscarinic Antagonist- M3 Urinary incontinance
Trihexyphenidyl
Benztropin
Muscarinic Antagonist Parkinsons - levels out excess cholinergic activation
Muscarinic Antagonist Parkinsons - levels out excess cholinergic activation