Nichole's Board Exam Review - Mixed Bag 1 Flashcards
The absorbed dose at a given depth expressed as a % of the absorbed dose at a reference depth (i.e. d-max) on the CAX of the field
PDD %DD
PDD is dependent on these 5 variables
- Energy
- Field Size
- SSD
- Depth
- Composition of the irradiated medium
Does PDD increase or decrease with …
- Increasing SSD?
- Increasing Field Size?
- Increasing Depth?
- Increasing SSD = Increasing PDD
- Increasing Field Size = Increasing PDD
- Increasing Depth = DECREASING PDD
- Dose in tissue / dose at d-max in a phantom
TMR
What is the most common type of thyroid cancer?
papillary
What 3 factors is TMR dependent on?
- Depth
- Energy
- Field Size
Talking about a patient’s treatment in an elevator that is filled with outside visitors is considered what kind of violation?
invasion of privacy
Define hyperfractionation
Multiple fractions increasing the daily dose; increasing the total dose while keeping the treatment time the same
Define accelerated fractionation
Multiple daily fractions that lead to a reduction in the overall treatment time (e.g. days).
What is the most curable type of leukemia?
ALL (Acute lymphocytic leukemia) starts in the bone marrow (the soft inner part of certain bones, where new blood cells are made)
List 5 signs & symptoms of AML (Acute myelogenous leukemia a cancer of the blood and bone marrow — the spongy tissue inside bones where blood cells are made.)
- weakness
- fatigue
- anemia
- bruising
- neutropenia (An abnormally low count of a type of white blood cell (neutrophils).
List 5 signs & symptoms of CML (Chronic myelogenous leukemia)
- fatigue
- fever
- night sweats
- weight loss
- enlarged spleen
List 6 signs & symptoms of ALL (Acute lymphocytic leukemia)
- non-specific viral symptoms
- low grade fever
- malaise (general feeling of discomfort, illness, or lack of well-being)
- anorexia
- lethargy (A condition marked by drowsiness and an unusual lack of energy and mental alertness
- abdominal discomfort
List 5 signs & symptoms of CLL (Chronic Lymphocytic Leukemia)
- fatigue
- malaise
- weight loss
- excessive sweating
- enlarged lymph nodes
List 2 reasons a bite block is used
- to help maintain the patient’s chin position
- moves the patient’s tongue out of the treatment area
(also to can be used when you want to displace the hard palate, mandible, or tongue away from the treatment volume)
What is used to calculate changes in PDD?
Mayneord’s factor
Where is the ampulla of vater?
where the common bile duct enters the duodenum
The ampulla of vater drains the ____ and ____ via the ____.
The ampulla of vater drains the liver and pancreas via the common bile duct.
medulloblastoma
- A childhood malignancy (ages 0-4
- 20-30% hereditary
- increased risk with Von Recklinghausen’s disease, Von Hipple-Lindau disease, Cowden’s disease, or Turcot’s syndrome.
- seeds to CSF
- craniospinal XRT
List the following cell types by order of decreasing sensitivity:
- crypt cells
- endothelial cells
- erythroblasts
- fibrocytes
- lymphocytes
- lymphocytes
- erythroblasts
- crypt cells
- endothelial cells
- fibrocytes
The stomach is located in which quadrant of the body?
upper left quadrant
Sterile techniques must be applied to ALL of the following EXCEPT?
- lumbar puncture
- blood culture
- lesion biopsy
- thoracentesis
- sputum culture
- sigmoidoscopy
- urine culture
- sputum culture
What are the 3 most radiosensitive organs in the body?
- gonads (testes & ovaries)
- bone marrow
- lens of the eye
What are the 3 most radioresistant organs in the body?
- ureters (7,000 cGy)
- urethra (7,000 cGy)
- vagina (9,000 cGy)
What 2 sets of lymph nodes are involved in the lymphatic drainage of the vulva?
- inguinal
- femoral
The parotid gland is located ____ and ____ to the EAM
- anterior
- inferior
Which of the following does a pancoast tumor NOT present with?
a. rib destruction
b. arm or shoulder pain
c. pulmonary artery invasion
d. brachial plexus involvement
c. pulmonary artery invasion
What is NOT a late effect of Mantle treatment?
a. pneumonitis
b. hypothyroidism
c. radiation carditis
d. low sperm count
d. low sperm count
What are the 2 most commonly treated sets of nodes for prostate cancer XRT?
- periprostatic
- obturator
What is the most common symList 3 primary risk factors for esophageal cancer?
hematuria
List 3 primary risk factors for esophageal cancer?
- smoking
- alcohol
- Barrett’s Esophagus
Dose in Tissue / Dose in Air
TAR
TAR depends on ____ and ____, but is independent of ____.
TAR depends on depth and field size, but is independent of SSD.
Define RBE
- Relative Biological Effect
- Dose in Gy from 250 kev x-ray / Dose in Gy from another radiation source that produces the same biologic response
Define LET
- Linear Energy Transfer
- Rate at which energy is deposited as a charged particle travels through matter by a particular type of radiation
List 5 symptoms associated with XRT of oral cavity
- xerostomia (dry mouth)
- loss of taste
- weight loss
- dental carries
- osteoradionecrosis ((ORN) of the mandible is a severe iatrogenic disease of devitalized bone caused by radiation therapy of oral and oropharyngeal cancers.
What is a 3-D field arrangement for esophageal cancer XRT?
AP/PA, then boost with 2 posterior obliques to spare the spinal cord
BSF
- Ratio of dose on the CAX at d-max to dose at the same point in air
- dose at d-max / dose in air
BSF is dependent on ____ and ____, but independent of _____.
BSF is dependent on energy and field size, but independent of SSD.
BSF and ___ at Dmax are the same.
TAR
Encircles the nasopharynx and oropharynx
Waldeyer’s ring
Put the following list in order according to which depletes first, second, etc.
Platelets 150 - 424 thousand/mm
Neutrophils 42% to 72%
Erythrocytes 3.9 - 5.90 million mm/3
Lymphocytes 17% to 45%
Lymphocytes
Neutrophils
Platelets (150 - 424 thousand/mm^3)
Erythrocytes (3.9 - 5.90 million/ mm^3
WBC ( 5, - 10.80 thousand/ mm^3)
Small, purplish hemorrhagic spots on the skin that appear in patient’s with thrombocytopenia are referred to as ____.
petechiae
If you notice that a patient has petechiae, what would do you?
a. Send the patient for blood work
b. Tell the patient to take iron supplements
c. Advise the patient about skin care
d. Notify the oncologist
a. Send the patient for blood work
List 4 symptoms of pancreatic cancer
- abdominal pain
- anorexia
- weight loss
- jaundice
List 6 symptoms of prostate cancer
- Weak or interrupted flow of urine
- Difficulty starting or stopping the stream of urine
- Increased frequency
- Hematuria
- Painful urination
- Pain in the lower back, pelvis, or upper thighs
Describe a 3D treatment technique for nasopharynx
Lateral neck fields with an anterior neck field that includes the S/C and lower cervical nodes
Describe the nodal drainage for the nasopharynx
- Retropharyngeal nodes (Node of Rouviere)
- Deep cervical nodes
- Jugulodigastric node
List 5 critical structures in the treatment of maxillary sinus
- Parotid
- Temporomandibular joint
- Lacrimal gland
- Spinal cord
- Lens
What are the routes of spread for testicular cancer?
- Para aortic nodes to pelvic nodes (iliac nodes)
- In later stages, can go from para aortic to the mediastinal and then the left S/C nodes by way of the thoracic duct
True or false? Retinoblastoma is hereditary.
true
Retinoblastoma (an eye cancer that begins in the back of the eye (retina) most commonly in children, in 1 or both eyes
List a common example of hyperfractionation
BID
hyperplasia`
increase in the NUMBER of cells
List 5 histologies of thyroid cancer
- medullary
- papillary
- squamous cell
- follicular
- anaplastic
Using an orthovoltage machine, what is the most common interaction with bone?
Compton scattering
inflammatory redness of the skin that resembles a sunburn; usually happens after about 2 weeks of XRT
erythema
shedding of the epidermis
dry desquamation
most of the cells of the basal layer are destroyed; the dermis then becomes exposed and begins producing a serous oozing from its surface
moist desquamation
Dry and moist desquamation may occur at around ____ to ____ cGy.
4500 - 6000 cGy
When would you use half beam blocking?
field abutment (match lines)
common in left breast pt
If XRT is the only treatment being used for Hodgkin’s disease, what is the normal dose prescribed for microscopic disease? Gross disease?
microscopic disease: 3000 - 3600 cGy
gross disease: 3600 - 4400 cGy
In what age group do you find the peak incidence of larynx cancer?
50 - 60 year olds
How many division of the larynx are there? What are they?
3 … supraglottic, glottic, & subglottic
Where do 65 - 75% of glottic lesions appear, in regards to the vocal cords?
on the anterior 2/3s of 1 vocal cord
single agent chemo used to treat breast cancer
tamoxifen
Which of the following is more radiosensitive?
a. esophagus
b. germinomas
c. teratomas
d. osteosarcomas
b. germinomas (relating to or having the nature of germ cells)
What is the vertebral level for the bifuration of the abdominal aorta?
L4
Why do you use a belly board when treating rectal cancer?
to allow the small bowel to fall anteriorly out of the treatment field
What is the dmax for 10MV?
2.5 cm
What is the dmax for 4MV?
1.0 cm
What is the dmax for 6MV?
1.5 cm
What is the dmax for 18MV?
3.5 cm
The practice that helps reduce the spread of microorganisms is referred to as ____.
asepsis
During treatment, the patient has complete cardiac failure. Their chart says DNR. What do you do?
call the doctor and wait with the pt
Why would Mantle & Inverted Y and ovarian cancer XRT impact the hemopoietic system the most?
These treatment fields include the largest amount of red bone marrow.
If your iso needs to move 0.5 cm anterior, how do you move the patient?
0.5 cm posterior
define thrombocytopenia
an abnormal decrease in the amount of platelets
caused by autoimmune disease such as lupus and rheumatoid arthritis
define thrombocytosis
having too many platelets
abnormal cells in the bone marrow can cause increase in platelets
hypertrophy
an increase in the size of cells
List 5 places where adult red bone marrow is found
- ribs
- ends of long bones
- vertebrae
- sternum
- skull bones
Which type of lung cancer follows a different treatment regimen?
small cell carcinoma
What is the formula for HVL?
.693 / M
Why do we include the lung when treating breast cancer?
to treat the chest wall and avoid a recurrence of disease
Where does the trachea start & end?
starts at C6 & ends at the carina
If the patient is prone and the doctor orders a 1.5 cm anterior shift, what direction would you move the table? In what direction would this move the CAX?
move the table upward, which would then move the CAX anteriorly
If the focal spot is out of alignment, what is the most plausible reason?
The mirror in the gantry head was accidentally knocked out of place
Most larynx cancers occur in which region?
Glottic (65%)
FYI: Supraglottic = 34% & Sublottic = 1%
Is cancer of the larynx more common in men or women?
men (5:1)
What is the most common malignant tumor encountered in the head & neck region?
larynx cancer
What is the most sensitive trimester in pregnancy with regard to radiation damage?
first trimester
What is the largest blood supply organ?
spleen
Name two organs that an urethrogram would be used for?
- bladder
2. kidneys
In what organ is a pancoast tumor found?
lung (at the very top of either lung)
Where does the spinal cord begin and end?
foramen magnum to L2
Reverse isolation protects ____ (whom?).
the patient
Where is the circumvallate papillae located?
base of tongue
What kind of surface should you perform CPR on?
flat surface
If a breast patient has skin folds, what’s something you can do (in treatment planning) to decrease their skin reaction?
add a wedge
What is the most sensitive part of the cell cycle?
M
What is the most resistant part of the cell cycle?
S
Describe the theory of Bergonie & Tribondeau
Ionizing radiation is more effective against cells that are actively dividing, are undifferentiated, and have a long dividing future
What is the most common neoplasm for children?
leukemia
What is the most common neoplasm for adults?
lung cancer
critical site is damaged by reactive species produced by ionization elsewhere in the cell, which in turn damages the target
indirect action
Put these parts of the machine in order: primary collimator, ion chamber, target, flattening filter
- Target
- Primary collimator
- Flattening filter
- Ion chamber
Put these structures in order from most radiosensitive to most radioresistant: brain, breast, lens, testes
- lens
- testes
- brain
- breast