Newborn Physiologic Adjustments (Immune System)

Question 1

IgG is key to immunity of what?

Answer 1

Bacteria and viruses

Question 2

The passive immunity afforded the infant through the placental transfer of IgG usually provides sufficient antimicrobial protection during the first ______ months of life.

Answer 2

3

Question 3

Production of adult concentrations of IgG is reached by ___ to ___ yrs.

Answer 3

4 to 6

Question 4

IgM is important for immunity to ______ infections?

Answer 4

Bloodborne infections.

Question 5

Are newborns capable of producing a protective immune response to vaccines?

Answer 5

Yes

Question 6

During the first several months of life, what is one of the leading causes of morbidity and morality in newborns?

Answer 6

Infections

Question 7

What are some early signs of serious infection?

Answer 7

Temperature instability or hypothermia. (temp greater than 100.4)

Question 8

What are some clinical signs of infection?

Answer 8

Lethargy 
Irritability 
Poor feeding
Vomiting 
Diarrhea
Decreased reflex
Pale or mottled skin color

Question 9

What are clinical signs associated with pneumonia?

Answer 9

Apnea
Tachypnea
Grunting
Retracting

Question 10

What is the greatest risk for neonatal infection?

Answer 10

prematurity because of immaturity of the immune system

Question 11

What are other common risks factors for infection?

Answer 11

Premature rupture of membranes
Chorioamnionitis
Maternal fever
Antenatal or intrapartal asphyxia
Invasive procedures
Stress
Congenital anomalies