Neurotransmitters Information (M2) Flashcards

1
Q

ACh postsynaptic effect

A

excitatory

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2
Q

glutamate postsynaptic effect

A

excitatory

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3
Q

GABA postsynaptic effect

A

inhibitory

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4
Q

glycine postsynaptic effect

A

inhibitory

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5
Q

catecholamines (epinephrine, norepinephrine, dopamine) postsynaptic effect

A

excitatory

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6
Q

serotonin (5-HT) postsynaptic effect

A

excitatory

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7
Q

histamine postsynaptic effect

A

excitatory

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8
Q

ATP postsynaptic effect

A

excitatory

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9
Q

neuropeptides postsynaptic effect

A

excitatory and inhibitory

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10
Q

endocannabinoids postsynaptic effect

A

inhibits inhibition

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11
Q

nitric oxide postsynaptic effect

A

excitatory and inhibitory

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12
Q

ACh precursors

A

choline + acetyl CoA

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13
Q

glutamate precursor

A

glutamine

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14
Q

GABA precursor

A

glutamate

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15
Q

glycine precursor

A

serine

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16
Q

catecholamines (epinephrine, norepinephrine, dopamine) precursor

A

tyrosine

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17
Q

serotonin (5-HT) precursor

A

tryptophan

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18
Q

histamine precursor

A

histidine

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19
Q

ATP precursor

A

ADP

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20
Q

neuropeptides precursor

A

amino acids (protein synthesis)

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21
Q

endocannabinoids precursor

A

membrane lipids

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22
Q

nitric oxide precursor

23
Q

ACh rate-limiting step in synthesis

24
Q

glutamate rate-limiting step in synthesis

A

glutaminase

25
GABA rate-limiting step in synthesis
GAD
26
catecholamines (epinephrine, norepinephrine, dopamine) rate-limiting step in synthesis
tyrosine hydroxylase
27
serotonin (5-HT) rate-limiting step in synthesis
tryptophan hydroxylase
28
histamine rate-limiting step in synthesis
histidine decarboxylase
29
ATP rate-limiting step in synthesis
mitochondrial oxidative phosphorylation; glycolysis
30
neuropeptides rate-limiting step in synthesis
synthesis and transport
31
endocannabinoids rate-limiting step in synthesis
enzymatic modification of lipids
32
nitric oxide rate-limiting step in synthesis
nitric oxide synthase
33
ACh removal mechanism
AChE
34
glutamate removal mechanism
transporters
35
GABA removal mechanism
transporters
36
glycine removal mechanism
transporters
37
catecholamines (epinephrine, norepinephrine, dopamine) removal mechanism
transporters, MAO, COMT
38
serotonin (5-HT) removal mechanism
transporters, MAO
39
histamine removal mechanism
transporters
40
ATP removal mechanism
hydrolysis to AMP and adenosine
41
neuropeptides removal mechanism
proteases
42
endocannabinoids removal mechanism
hydrolysis by FAAH
43
nitric oxide removal mechanism
spontaneous oxidation
44
ACh type of vesicle
small, clear
45
glutamate type of vesicle
small, clear
46
GABA type of vesicle
small, clear
47
catecholamines type of vesicle
small, dense-core or large, irregular dense-core
48
serotonin type of vesicle
large, dense-core
49
histamine type of vesicle
large, dense-core
50
ATP type of vesicle
small, clear
51
neuropeptides type of vesicle
large, dense-core
52
endocannabinoids type of vesicle
none
53
nitric oxide type of vesicle
none