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OPT 112 > Neurotransmitters Information (M2) > Flashcards

Neurotransmitters Information (M2) Flashcards

1
Q

ACh postsynaptic effect

A

excitatory

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2
Q

glutamate postsynaptic effect

A

excitatory

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3
Q

GABA postsynaptic effect

A

inhibitory

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4
Q

glycine postsynaptic effect

A

inhibitory

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5
Q

catecholamines (epinephrine, norepinephrine, dopamine) postsynaptic effect

A

excitatory

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6
Q

serotonin (5-HT) postsynaptic effect

A

excitatory

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7
Q

histamine postsynaptic effect

A

excitatory

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8
Q

ATP postsynaptic effect

A

excitatory

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9
Q

neuropeptides postsynaptic effect

A

excitatory and inhibitory

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10
Q

endocannabinoids postsynaptic effect

A

inhibits inhibition

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11
Q

nitric oxide postsynaptic effect

A

excitatory and inhibitory

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12
Q

ACh precursors

A

choline + acetyl CoA

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13
Q

glutamate precursor

A

glutamine

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14
Q

GABA precursor

A

glutamate

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15
Q

glycine precursor

A

serine

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16
Q

catecholamines (epinephrine, norepinephrine, dopamine) precursor

A

tyrosine

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17
Q

serotonin (5-HT) precursor

A

tryptophan

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18
Q

histamine precursor

A

histidine

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19
Q

ATP precursor

A

ADP

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20
Q

neuropeptides precursor

A

amino acids (protein synthesis)

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21
Q

endocannabinoids precursor

A

membrane lipids

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22
Q

nitric oxide precursor

A

arginine

23
Q

ACh rate-limiting step in synthesis

A

ChAT

24
Q

glutamate rate-limiting step in synthesis

A

glutaminase

25
Q

GABA rate-limiting step in synthesis

A

GAD

26
Q

catecholamines (epinephrine, norepinephrine, dopamine) rate-limiting step in synthesis

A

tyrosine hydroxylase

27
Q

serotonin (5-HT) rate-limiting step in synthesis

A

tryptophan hydroxylase

28
Q

histamine rate-limiting step in synthesis

A

histidine decarboxylase

29
Q

ATP rate-limiting step in synthesis

A

mitochondrial oxidative phosphorylation; glycolysis

30
Q

neuropeptides rate-limiting step in synthesis

A

synthesis and transport

31
Q

endocannabinoids rate-limiting step in synthesis

A

enzymatic modification of lipids

32
Q

nitric oxide rate-limiting step in synthesis

A

nitric oxide synthase

33
Q

ACh removal mechanism

A

AChE

34
Q

glutamate removal mechanism

A

transporters

35
Q

GABA removal mechanism

A

transporters

36
Q

glycine removal mechanism

A

transporters

37
Q

catecholamines (epinephrine, norepinephrine, dopamine) removal mechanism

A

transporters, MAO, COMT

38
Q

serotonin (5-HT) removal mechanism

A

transporters, MAO

39
Q

histamine removal mechanism

A

transporters

40
Q

ATP removal mechanism

A

hydrolysis to AMP and adenosine

41
Q

neuropeptides removal mechanism

A

proteases

42
Q

endocannabinoids removal mechanism

A

hydrolysis by FAAH

43
Q

nitric oxide removal mechanism

A

spontaneous oxidation

44
Q

ACh type of vesicle

A

small, clear

45
Q

glutamate type of vesicle

A

small, clear

46
Q

GABA type of vesicle

A

small, clear

47
Q

catecholamines type of vesicle

A

small, dense-core or large, irregular dense-core

48
Q

serotonin type of vesicle

A

large, dense-core

49
Q

histamine type of vesicle

A

large, dense-core

50
Q

ATP type of vesicle

A

small, clear

51
Q

neuropeptides type of vesicle

A

large, dense-core

52
Q

endocannabinoids type of vesicle

A

none

53
Q

nitric oxide type of vesicle

A

none

OPT 112 (9 decks)

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