Neuroscience Flashcards
what part of the brain synthesizes NE
locus cereulus
what is the precursor to 5HT
tryptophan
where does COMT act
post synaptic membrane
what is the precursor to DA
tyrosine
What is the precursor to NE
dopamine
What is the precursor to GABA
glutamate
what part of the brain synthesizes 5HT
raphe nucelus (brainstem)
what part of the brain synthesizes Da
substantia nigra
name the GABA receptors
A, B and C
what is a metabolite of 5HT
melatonin
which neurotransmitter does not act centrally
adrenaline
what is the purpose of the medulla oblongata
located in the brainstem and is responsible for basic life fnx (i.e breathing)
which two NT are responsible for chorea in Huntington’s
decrease DA and GABA
where is the subthalamic nuclei located
basal ganglia
what are the two situations CT is better than MRI
- acute bleed 2. calcification
what is semantic memory
facts
akinetic mutism is most commonly associated with which d/o
brainstem lesion
which part of the brain does korsakoff effect
mammillary bodies and thalamus
which gender has a bigger corpus callosum
F
EEG finding in hepatic encephalopathy
triphasic waves
Name the three areas of the frontal cortex and their associated impairment when damaged
- orbitofrontal (disinibition) 2. medial frontal (apathy) 3. dorsolateral (exe dysfnx)
what does sodium amytal do to sz threshold
increase it
what is a lesion in the left parietal lobe called
Gertsmann syndrome
what does an individual in left parietal lobe present with
aphasia, agnosia, acalculia, agraphia, and right left confusion
what does fMRI measure
blood flow
which type of dementia is primary progressive aphasia
FTD
where should electrodes be placed for DBS of depression
subcallosal cingulate gyrus
first deficit of PPA
anomia
what percent of MCI convert to dementia every yr
12%
prevalence of MCI in elderly
2-10% in over 65
lesion in left frontal inferior region causes what impairment
inability to name (broca’s located there)
lesion in left perisilvian fissure causes what impairment
inability to comprehend (wernickes located there)
which artery supplied the brain region responsible for sensation and language
MCA
what is the difference bw DLPC and orbitofrontal cortex
DLPC does executive func and orbito more decision making based on reward.
a lesion in which area leads to neglect
non-dominant parietal lobe
pernicious anemia is deficiency in which vitamin
b12
