Neuroscience Flashcards

1
Q

what part of the brain synthesizes NE

A

locus cereulus

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2
Q

what is the precursor to 5HT

A

tryptophan

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3
Q

where does COMT act

A

post synaptic membrane

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4
Q

what is the precursor to DA

A

tyrosine

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5
Q

What is the precursor to NE

A

dopamine

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6
Q

What is the precursor to GABA

A

glutamate

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7
Q

what part of the brain synthesizes 5HT

A

raphe nucelus (brainstem)

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8
Q

what part of the brain synthesizes Da

A

substantia nigra

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9
Q

name the GABA receptors

A

A, B and C

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10
Q

what is a metabolite of 5HT

A

melatonin

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11
Q

which neurotransmitter does not act centrally

A

adrenaline

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12
Q

what is the purpose of the medulla oblongata

A

located in the brainstem and is responsible for basic life fnx (i.e breathing)

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13
Q

which two NT are responsible for chorea in Huntington’s

A

decrease DA and GABA

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14
Q

where is the subthalamic nuclei located

A

basal ganglia

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15
Q

what are the two situations CT is better than MRI

A
  1. acute bleed 2. calcification
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16
Q

what is semantic memory

A

facts

17
Q

akinetic mutism is most commonly associated with which d/o

A

brainstem lesion

18
Q

which part of the brain does korsakoff effect

A

mammillary bodies and thalamus

19
Q

which gender has a bigger corpus callosum

A

F

20
Q

EEG finding in hepatic encephalopathy

A

triphasic waves

21
Q

Name the three areas of the frontal cortex and their associated impairment when damaged

A
  1. orbitofrontal (disinibition) 2. medial frontal (apathy) 3. dorsolateral (exe dysfnx)
22
Q

what does sodium amytal do to sz threshold

A

increase it

23
Q

what is a lesion in the left parietal lobe called

A

Gertsmann syndrome

24
Q

what does an individual in left parietal lobe present with

A

aphasia, agnosia, acalculia, agraphia, and right left confusion

25
Q

what does fMRI measure

A

blood flow

26
Q

which type of dementia is primary progressive aphasia

A

FTD

27
Q

where should electrodes be placed for DBS of depression

A

subcallosal cingulate gyrus

28
Q

first deficit of PPA

A

anomia

29
Q

what percent of MCI convert to dementia every yr

A

12%

30
Q

prevalence of MCI in elderly

A

2-10% in over 65

31
Q

lesion in left frontal inferior region causes what impairment

A

inability to name (broca’s located there)

32
Q

lesion in left perisilvian fissure causes what impairment

A

inability to comprehend (wernickes located there)

33
Q

which artery supplied the brain region responsible for sensation and language

A

MCA

34
Q

what is the difference bw DLPC and orbitofrontal cortex

A

DLPC does executive func and orbito more decision making based on reward.

35
Q

a lesion in which area leads to neglect

A

non-dominant parietal lobe

36
Q

pernicious anemia is deficiency in which vitamin

A

b12