Depression Flashcards

1
Q

Kids with DMDD are more likely to develop what?

A

MDD or anxiety

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2
Q

How long do DMDD sx need to be present for?

A

1 year

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3
Q

In DMDD, temper outbursts how many x/week?

A

3 or more

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4
Q

DMDD cannot co-exist with which three other d/o?

A

ODD, intermittent explosive, bipolar

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5
Q

DMDD can only be made between the ages of?

A

6-10

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6
Q

Does DMDD trump a bipolar dx?

A

No

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7
Q

Does DMDD trump an ODD dx?

A

Yes

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8
Q

Difference bw grief and MDD

A

Comes in waves
Predominant feelings of emptiness and loss
Rare to have guilt, worthlessness, SI or psychomotor
Self esteem is preserved
Onset within 2 mo of death and does not last more than 2 mo

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9
Q

Prevalence of depression at 12 months?

A

7%

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10
Q

When does depression peak?

A

In 20s and 40s

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11
Q

When does recovery being?

A

Within 3 months in 2/5 and 1 yr for 4/5

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12
Q

What is the gender difference in MDD epi?

A

Difference in prevalence (females are 3x higher) but not in response or course

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13
Q

T/F- suicide attempts decrease with age but completed suicides do not

A

True

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14
Q

There is memory loss for recent and remote events in

A

pseudodementia

In dementia the memory loss is just for recent

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15
Q

Recurrence of depression in 6m,2y,5y

A

25, 50, 75%

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16
Q

Post stroke depression most common on which hemisphere?

A

Left

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17
Q

Early onset PDD is before age

A

21

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18
Q

What is the time course of PMDD

A

sx present in the week before menses (luteal phase), improve with start of menses and absent in the week post menses

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19
Q

Criteria for PMDD

A

B) lability, irritability, depressed mood, anxiety

C) SIECA, overwhelmed, out of ctrl, physical sx (bloating)

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20
Q

Do sx of PMDD worsen as they approach menopause

A

Yes

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21
Q

Anxious distress specifier is

A

At least two of: keyed up, restless, decreased conc,fear that something awful may happen, fear of losing ctrl

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22
Q

Melancholic feature criteria include

A

A) Anhedonia!

B) Three or more: depression, worse in am, early morning awakening, agitation or retardation, weight loss, guilt

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23
Q

Melancholic depression predicts

A

psychosis

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24
Q

Atypical depression is also known as

A

Hysteroid dysphoria

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25
Q

Atypical depression criteria include

A

A) mood reactivity

B) Two or more: hypersomnolence, increased appetite, leaden paralysis, interpersonal issues

26
Q

T/F- Atypical depression responds better to MAOIs than TCAs

A

T

27
Q

What timespan includes peripartum dep onset

A

during pregnancy or 4 w post partum

28
Q

In seasonal pattern do you need full remission in the “non-season”? T/F

A

False

Full remission OR a change i.e (dep to mania)

29
Q

Seasonal pattern is most likely in which d/o

A

BPII

30
Q

Can you have non seasonal depression and still meet criteria for SAD?

A

yes, as long as seasonal outnumbers non-seasonal in the individual’s lifetime

31
Q

Describe the mood in between outbursts in DMDD

A

persistently irritable

32
Q

How long does DMDD sx have to be present for?

A

1 yr

33
Q

What age group can the DMDD dx NOT be made?

A

Less than 6 and after 18

34
Q

What percentage of post partum depression depression starts during pregnancy?

A

50%

35
Q

Other than depression what other d/o increases risk of post partum depression?

A

Anxiety, panic attacks

36
Q

Risk of post partum psychosis is increased for which three groups of women?

A
  1. past post partum mood episodes 2. hx of mood episodes (particuarly BPI) 3. family hx of BP
37
Q

What’s the risk of having another post partum psychosis if you’ve already had one?

A

30-50%

38
Q

First line complementary tx for MDD

A
  1. Light 2. exercise 3. St. Johns
39
Q

T/F CBT= light therapy in acute MDD

A

T

40
Q

T/F CBT = light therapy in the long term for MDD

A

F- CBT is better 2 yrs later

41
Q

AD should be switched if there is only minimal improvement after how long?

A

2-4 weeks

42
Q

1st line augmenting meds (name 3)

A

abilify= quetiapine= risperidone

43
Q

What % of PDD progress to bipolar and depression?

A

20% (5% I and 15%II) and 20%

44
Q

Difference in length between baby blues and PP depression.

A

3-5 days versus 3-6 months

45
Q

Atypical depression is a predictor of which other disorder

A

BPI

46
Q

Atypical depression is co-morbid with which two other dx

A
  1. social phobia 2. avoidant PD
47
Q

Most common cause of death in a depressed pt?

A

Cardiovascular disease

48
Q

Which three meds have no RCT evidence for agumenting but are 3rd line?

A
  1. methylphenidate 2. AD (other than buproprion and mirt) 3. ziprasidone
49
Q

In depression REM moves from which part of sleep?

A

Moves from later to earlier

50
Q

AD do what to REM?

A

Suppress REM

51
Q

In depression how does TSH respond to TRH?

A

Decreased response

52
Q

Which one medication is not recommended as an adjunct in MDD

A

pindolol

53
Q

Does rTMS cause seizures?

A

Can happen but it is not intended

54
Q

What is the one absolute contraindication in rTMS?

A

metallic hardware in the head ,except the mouth

55
Q

What two regions of the brain have decreased metabolic activity in seasonal patterned illness?

A
  1. orbital frontal cortex 2. left inferior parietal lobe
56
Q

In mild depression with concurrent ADHD, which do you treat first?

A

ADHD

only if severe SI then tx MDD first

57
Q

During which time period after admission is someone most likely to complete suicide

A

3 mo after d/c

58
Q

for which gender does the risk of suicide decrease with age

A

females

59
Q

what pattern does male suicide risk follow across the lifespan

A

two peaks

60
Q

most common psyc manifestation of hyperparathyroidism

A

depression with anergia