Neuropharm anticholinergic

Question 1

Anticholinergic drugs act by __ cholinergic transmission

Answer 1

Decreasing

Question 2

Another name for anticholinergic drugs

Answer 2

Muscarinic antagonists

Question 3

Commonly used anticholinergic medications

Answer 3

Benztropine
Oxybutynin
Atropine
Scopolamine

BOAtS

Glycopyrrolate
Ipratopium
Dicyclomine
Hyscyamine

Question 4

Anticholinergic meds work to prevent transmission at muscarinic receptors and therefore do what

Answer 4

Prevent a parasympathetic nervous system response

Question 5

What is benztropine used for

Answer 5

With levodopa for Parkinson’s

Often used for parkinsonian symptoms which can accompany antipsychotic medications

Question 6

How does benztropine help with Parkinson’s

Answer 6

Antagonize the effects of acetylcholine

Reducing the imbalance between acetylcholine and dopamine which helps prevent parkinsonian symptoms.

Question 7

How does oxybutynin work

Answer 7

Inhibits muscarinic action of acetylcholine on smooth muscle

Question 8

What does oxybutynin do

Answer 8

Decrease bladder spasm

Question 9

Indication for oxybutynin

Answer 9

Frequent urination and urge incontinence
Overactive bladder
It will decrease frequent urination

Question 10

Atropine has numerous uses. What are some

Answer 10

Cycloplegic and dilates pupil
To treat bradycardia as it blocks the actions of the vagus nerve
To increase heart rate
Reverse organophosphate poisoning
Decrease secretions and bronchoconstriction

Question 11

Int he eye, atropine induces ____

Answer 11

Mydriasis or pupil dilation

Question 12

Atropine can be used to treat what

Answer 12

Cycloplegia

Or paralysis of the accommodation reflex

Question 13

Scopolamine can be given orally, IV or transdermally. For what

Answer 13

Treat motion sickness and has amnestied and sedative properties

Question 14

How does scopolamine treat motion sickness

Answer 14

Blocking muscarinic receptors in the CNS and the vestibular system

Question 15

Why is scopolamine used over atropine for motion sickness

Answer 15

Longer acting and has greater action not he CNS

Question 16

Glycopyrrolate

Answer 16

Decrease airway secretions, in addition to decreasing stomach acid secretions in peptic ulcer disease.
Also prevents bradychardia, which occurs with the administration or neostigmine. Thus glycopyrrolate is often given to patients with neuromuscluar blocking reversal agent, neostigmine

Question 17

How does glycopyrrolate reduce airway secretion

Answer 17

Prevent salivary, pharyngeal and trachiobronchial secretions. Helps with intubation in anesthesia as well as maintaining open airways during ventilation

Question 18

How can glycopyrrolate treat ulcer

Answer 18

Helps decrease stomach acid secretion and is helpful in treating peptic ulcers

Question 19

Ipratopium

Answer 19

Inhalation medication used to treat COPD and acute asthma

Question 20

Ipratropium is typically used to treat acute asthma, but is usually combined with what

Answer 20

Long acting b agonist

Question 21

Dicyclomine

Answer 21

Anticholinergic medication that blocks muscarinic receptors and is used to treat intestinal hypermotility and IBS by reducing gastric spasms

Question 22

Hyoscyamine

Answer 22

Antagonist of muscarinic ach receptors, working to block parasympathetic activity.

Question 23

Bc hyocyamine blocks parasympathetic activity of smooth muscle of the gut, it is indicated for what

Answer 23

Use in various gastrointestinal disorders, such as irritable bowel syndrome

Question 24

What is IBS

Answer 24

Syndrome is gastrointestinal disorder characterized by abdominal pain, alterations in bowel patterns of diarrhea and constipation , excessive flatulence and fatigue . Symptoms reduced by defecation

Question 25

What is atropine

Answer 25

Muscarinic antagonist used in ophthalmic applications, organophosphate overdose, and cases of bradycardia

Question 26

Side effects of atropine

Answer 26

Skin flushing , increased temperature, dry mouth, cycloplegiaa and disorientation in the elderly
Mydriasis

Question 27

What are the indications for atropine “DUMBBeLSS” it blocks these

Answer 27

Diarrhea, urination, miosis, bradychardia, bronchoconstriction, lacrimation, salivation, and sweating

Question 28

What kind of receptors does atropine block

Answer 28

Muscarinic receptors

Question 29

What receptors block CNS excitation

Answer 29

Nicotonic

Question 30

What is atropine used for

Answer 30

Antidote in cholinergic poisoning or organophosphate poisoning, acting by blocking acetylcholine action at muscarinic receptors