neuropathy Flashcards
Seddon’s Classification
Neurotmesis
Axonotmesis
Neuropraxia
Sunderland’s classification
Class I: First degree
Class II: 2nd deg-4th deg
Class III: 5th degree
3 classes of injury: 5 degrees
Neurotmesis
MOST devistating nerve injury
complete disruption of nerve along with its connective tissue (ie from laceration, fractures, gunshots)
-neurites cannot bridge and bud
Neurotmesis tx
requires surgical intervention:
-resect necrotic tissue, realign fasculi
Nerve fiber growth rate
regeneration ~1 mm/day
Axonotmesis
axon disruption but supportive CT is maintained
new axons are able to regenerate and grow down corresponding endoneural tube
disruption to myelinated and unmyelinated axons
Wallerian degernation
degeneration of the axons distally
neuropraxia
transient block: disruption of myelin sheath
short lived paralysis may develop
repair can cause days to months
Class I:
1st degree
1st: conduction deficit w/o axon interruption -equivalent to Neuropraxia
Class II:
2nd degree
3rd
4th
2nd: axon severed w/o breaching the endoneurium
- breakdown of myelin and wallerian degneration
- regeneration follows pattern of axonal regrowth
- equivalent to seddons axonotmesis
3rd:
- nerve fiber disruption, lesion in endoneurum (epineurium and perineurieum intact), recovery is possible but may need surgery
- regeneration is often irregular and residual deficit
4th: only epineum remains in tact, requires surgical repair
Class III: 5th degree
complete transection of nerve, requires surgical repair
tinel vs villeix
tinel: tingling goes distally (TD–>touch down)
Villeix: tingling going proximally (VP)
Common sites for peripheral nerve entrapment
adductor canal: saphenous nerve
fibular head/neck: common peronal nerve
Deep fascial proximal to ankle: superficial peroneal nerve
lateral malleolus: sural nerve
borders of tarsal tunnel
Anterior: tibia:
lateral: posterior process talus and calcaneus
medial: flexor retinaculum
what are some clinical signs of tarsal tunnel syndrome
pain aggravated by standing and relieved with rest–>
some may have worse at night and better throughout day with activity
may have raediating to prox calf